Interleukin-8 and the chemokine family

Van Damme A.

1986 • 3,477 citations

Interleukin-8 and related chemotactic cytokines--CXC and CC chemokines.

1994 • 2,251 citations

lnterleukin-8 and Related Chemotactic Cytokines—CXC and CC Chemokines

1993 • 1,650 citations

Structure and Functional Expression of a Human Interleukin-8 Receptor

1991 • 1,088 citations

The Neutrophil-Activating Protein (NAP-1) Is Also Chemotactic for T Lymphocytes

1989 • 1,060 citations

Purification of a human monocyte-derived neutrophil chemotactic factor that has peptide sequence similarity to other host defense cytokines.

1987 • 983 citations

Cloning of Complementary DNA Encoding a Functional Human Interleukin-8 Receptor

1991 • 878 citations

Purification and characterization of a novel monocyte chemotactic and activating factor produced by a human myelomonocytic cell line.

1989 • 753 citations

Biology and biochemistry of the chemokines: a family of chemotactic and inflammatory cytokines.

1992 • 737 citations

Preferential Migration of Activated CD4 ⁺ and CD8 ⁺ T Cells in Response to MIP-1α and MIP-1β

1993 • 737 citations

RANTES and macrophage inflammatory protein 1 alpha induce the migration and activation of normal human eosinophil granulocytes.

1992 • 620 citations

Monocyte chemoattractant protein-1 regulates adhesion molecule expression and cytokine production in human monocytes.

1992 • 509 citations

Neutrophil elastase in respiratory epithelial lining fluid of individuals with cystic fibrosis induces interleukin-8 gene expression in a human bronchial epithelial cell line.

1992 • 498 citations

Elevated Levels of NAP-1/Interleukin-8 Are Present in the Airspaces of Patients with the Adult Respiratory Distress Syndrome and Are Associated with Increased Mortality

1992 • 472 citations

Expression of the potent inflammatory cytokines, granulocyte-macrophage-colony-stimulating factor and interleukin-6 and interleukin-8, in bronchial epithelial cells of patients with asthma

1992 • 408 citations

Scanning mutagenesis of interleukin-8 identifies a cluster of residues required for receptor binding.

1991 • 372 citations

Structural and functional identification of two human, tumor-derived monocyte chemotactic proteins (MCP-2 and MCP-3) belonging to the chemokine family.

1992 • 365 citations

IL-8 in septic shock, endotoxemia, and after IL-1 administration.

1991 • 313 citations

Purification and amino acid analysis of two human monocyte chemoattractants produced by phytohemagglutinin-stimulated human blood mononuclear leukocytes.

1989 • 304 citations

Platelet factor 4 binds to interleukin 8 receptors and activates neutrophils when its N terminus is modified with Glu-Leu-Arg.

1993 • 262 citations

Properties of monocyte chemotactic and activating factor (MCAF) purified from a human fibrosarcoma cell line.

1990 • 241 citations

Neutrophil-activating peptide 2 and gro/melanoma growth-stimulatory activity interact with neutrophil-activating peptide 1/interleukin 8 receptors on human neutrophils

1991 • 225 citations

The role of cytokines in the pathogenesis of inflammatory eye disease

1992 • 218 citations

Monocyte chemotactic protein 1 is a potent activator of human basophils.

1992 • 218 citations

RANTES and related chemokines activate human basophil granulocytes through different G protein‐coupled receptors

1993 • 216 citations

In vivo inflammatory activity of neutrophil-activating factor, a novel chemotactic peptide derived from human monocytes.

1989 • 198 citations

Leukocyte specificity and binding of human neutrophil attractant/activation protein-1.

1990 • 189 citations

High- and low-affinity binding of GRO alpha and neutrophil-activating peptide 2 to interleukin 8 receptors on human neutrophils.

1992 • 189 citations

Monocyte chemotactic and activating factor is a potent histamine-releasing factor for human basophils.

1992 • 182 citations

Neutrophilic Alveolitis in Idiopathic Pulmonary Fibrosis: The Role of Interleukin-8

1992 • 180 citations

Expression of macrophage inflammatory protein-2 and KC mRNA in pulmonary inflammation.

1992 • 177 citations

Interleukin-8 antagonists generated by N-terminal modification.

1993 • 138 citations

Expression of transcripts for two interleukin 8 receptors in human phagocytes, lymphocytes and melanoma cells

1993 • 132 citations

Neutrophil Recruitment by Intradermally Injected Neutrophil Attractant/Activation Protein-1

1991 • 125 citations

Shape changes, exocytosis, and cytosolic free calcium changes in stimulated human eosinophils.

1991 • 121 citations

Interleukin-8 Is a Major Neutrophil Chemotactic Factor in Pleural Liquid of Patients with Empyema

1992 • 121 citations

Uncoupling of early signal transduction events from effector function in human peripheral blood neutrophils in response to recombinant macrophage inflammatory proteins-1 alpha and -1 beta.

1993 • 93 citations

Activation of human basophils through the IL-8 receptor.

1992 • 82 citations

Evidence of a role for mesothelial cell-derived interleukin 8 in the pathogenesis of asbestos-induced pleurisy in rabbits.

1992 • 72 citations

HepG2 cells predominantly express the type II interleukin 1 receptor (biochemical and molecular characterization of the IL-1 receptor)

1992 • 29 citations

Cytokines, vol 4: Interleukin-8(NAP-1) and Related Chemotactic Cytokines

1992 • 3 citations