Normal Cholesterol Levels With Lovastatin (Mevinolin) Therapy in a Child With Homozygous Familial Hypercholesterolemia Following Liver Transplantation

A Receptor-Mediated Pathway for Cholesterol Homeostasis

1986 • 5,638 citations

Nelson Textbook of Pediatrics

1976 • 5,108 citations

The metabolism of very low density lipoprotein proteins I. Preliminary in vitro and in vivo observations

1972 • 1,831 citations

Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent.

1980 • 1,607 citations

Mevinolin and colestipol stimulate receptor-mediated clearance of low density lipoprotein from plasma in familial hypercholesterolemia heterozygotes.

1983 • 562 citations

Lipoprotein receptors in the liver. Control signals for plasma cholesterol traffic.

1983 • 548 citations

Liver Transplantation to Provide Low-Density-Lipoprotein Receptors and Lower Plasma Cholesterol in a Child with Homozygous Familial Hypercholesterolemia

1984 • 442 citations

Enhanced binding by cultured human fibroblasts of apo-E-containing lipoproteins as compared with low density lipoproteins

1978 • 430 citations

Regulatory role for hepatic low density lipoprotein receptors in vivo in the dog.

1981 • 424 citations

HEART-LIVER TRANSPLANTATION IN A PATIENT WITH FAMILIAL HYPERCHOLESTEROLAEMIA

1984 • 359 citations

Compactin (ML-236B) and related compounds as potential cholesterol-lowering agents that inhibit HMG-CoA reductase

1985 • 285 citations

Selective removal of low density lipoprotein by plasmapheresis in familial hypercholesterolemia.

1985 • 254 citations

Reduction in cholesterol and low density lipoprotein synthesis after portacaval shunt surgery in a patient with homozygous familial hypercholesterolemia.

1975 • 245 citations

Therapeutic effects of ML-236B in primary hypercholesterolemia

1980 • 231 citations

Familial Hypercholesterolemia: A Genetic Defect in the Low-Density Lipoprotein Receptor

1976 • 220 citations

Metabolic Studies in Familial Hypercholesterolemia

1979 • 217 citations

Influence of mevinolin on metabolism of low density lipoproteins in primary moderate hypercholesterolemia.

1985 • 210 citations

Reduction of Serum Cholesterol in Heterozygous Patients with Familial Hypercholesterolemia

1983 • 201 citations

Normalization of Low-Density-Lipoprotein Levels in Heterozygous Familial Hypercholesterolemia with a Combined Drug Regimen

1981 • 197 citations

Accelerated atherosclerosis in cardiac transplantation: role of cytotoxic B-cell antibodies and hyperlipidemia.

1983 • 177 citations

Studies on the pathogenesis of atheroarteriosclerosis induced in rabbit cardiac allografts by the synergy of graft rejection and hypercholesterolemia.

1977 • 171 citations

Selective removal of apolipoprotein B-containing serum lipoproteins from blood plasma.

1981 • 171 citations

Measurement of glomerular filtration rate utilizing a single subcutaneous injection of 125I-iothalamate

1973 • 151 citations

Cholestyramine-induced changes in low density lipoprotein composition and metabolism. I. Studies in the guinea pig.

1985 • 110 citations

Control of graft arteriosclerosis in human heart transplant recipients.

1977 • 108 citations

Portacaval Shunt in Patients with Familial Hypercholesterolemia

1983 • 71 citations

Receptor-independent catabolism of low density lipoprotein. Involvement of the reticuloendothelial system.

1982 • 50 citations

Kinetic defects in the processing of the low density lipoprotein receptor in fibroblasts from WHHL rabbits and a family with familial hypercholesterolemia.

1983 • 44 citations

Probucol with Colestipol in the Treatment of Hypercholesterolemia

1984 • 38 citations

Elevated Cholesterol and Bile Acid Synthesis in a Young Patient with Homozygous Familial Hypercholesterolemia

1979 • 34 citations

Effects of ML-236B (Compactin) on Sterol Synthesis and Low Density Lipoprotein Receptor Activities in Fibroblasts of Patients with Homozygous Familial Hypercholesterolemia

1981 • 31 citations

Elevated cholesterol and bile acid synthesis in an adult patient with homozygous familial hypercholesterolemia. Reduction by a high glucose diet.

1981 • 26 citations