Acute sensitivity vs. context-specific sensitization to cocaine as a function of genotype

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1982 • 22,508 citations

The neural basis of drug craving: An incentive-sensitization theory of addiction

1993 • 7,074 citations

Dopamine transmission in the initiation and expression of drug- and stress-induced sensitization of motor activity

1991 • 2,025 citations

Factors That Predict Individual Vulnerability to Amphetamine Self-Administration

1989 • 1,354 citations

Sensitization in the Nervous System

2024 • 359 citations

Dopaminergic activity is reduced in the prefrontal cortex and increased in the nucleus accumbens of rats predisposed to develop amphetamine self-administration

1991 • 335 citations

Estimation of Genetic Correlation: Interpretation of Experiments Using Selectively Bred and Inbred Animals

1990 • 322 citations

Drug-environment interaction: Context dependency of cocaine-induced behavioral sensitization

1981 • 309 citations

Sensitization to cocaine stimulation in mice

1977 • 260 citations

Pimozide Blocks Establishment But Not Expression of Amphetamine-Produced Environment-Specific Conditioning

1983 • 256 citations

Amphetamine administered to the ventral tegmental area but not to the nucleus accumbens sensitizes rats to systemic morphine: lack of conditioned effects

1990 • 251 citations

Context-Dependent Cocaine Sensitization: Differential Effect of Haloperidol on Development Versus Expression

1989 • 182 citations

Sensitization to repeated morphine injection in the rat: possible involvement of A10 dopamine neurons.

1987 • 176 citations

A Lasting Vulnerability to Psychosis in Patients with Previous Methamphetamine Psychosis

1992 • 155 citations

The neurobiology of Drug and alcohol addiction

1991 • 154 citations

Sensitization occurs to the locomotor effects of morphine and the specific μ opioid receptor agonist, DAGO, administered repeatedly to the ventral tegmental area but not to the nucleus accumbens

1987 • 152 citations

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1982 • 144 citations

Individual differences in amphetamine sensitization: Dose-dependent effects

1992 • 141 citations

Enhancing effect of methamphetamine on ambulatory activity produced by repeated administration in mice

1981 • 134 citations

D1 and D2 receptor antagonists differently affect cocaine-induced locomotor hyperactivity in the mouse

1991 • 131 citations

Conditioning as a critical determinant of sensitization induced by psychomotor stimulants.

1990 • 117 citations

Genotypic influences on striatal dopaminergic regulation in mice

1981 • 95 citations

Two dissociable components of behavioral sensitization following repeated amphetamine administration

1982 • 87 citations

An analysis of cocaine effects on locomotor activities and heart rate in four inbred mouse strains

1988 • 82 citations

Inbred rat strain comparisons indicate different sites of action for cocaine and amphetamine locomotor stimulant effects

1991 • 77 citations

Opioid operant self-administration, analgesia, stimulation and respiratory depression inμ-deficient mice

1995 • 75 citations

Chronic stress induces strain-dependent sensitization to the behavioral effects of amphetamine in the mouse

1992 • 67 citations

Increased running response to morphine in morphine-pretreated mice.

1975 • 65 citations

Brain locations controlling the behavioral effects of chronic amphetamine intoxication

1980 • 63 citations

Changes in brain norepinephrine associated with sensitization to d-amphetamine

1976 • 62 citations

Tolerance to morphine in the rat: Associative and nonassociative effects.

1988 • 51 citations

Amphetamine-induced hypolocomotion in mice with more brain D2 dopamine receptors

1982 • 44 citations

Cocaine produces locomotor stimulation in SS but not LS mice: Relationship to dopaminergic function

1990 • 41 citations

Tolerance to morphine in the rat: Associative and nonassociative effects.

1988 • 41 citations

Fixed-ratio schedules of oral ethanol self-administration in inbred mouse strains

1988 • 40 citations

Orally delivered cocaine functions as a positive reinforcer in C57BL/6J mice

1991 • 39 citations

Strain-dependent behavioural sensitization to amphetamine

1993 • 38 citations

Cocaine produces low dose locomotor depressant effects in mice

1989 • 34 citations

Cocaine binding sites in mouse striatum, dopamine autoreceptors, and cocaine-induced locomotion

1992 • 34 citations

Controlling interindividual differences in the unconditioned response to amphetamine in the study of environment-dependent sensitization

1993 • 29 citations

Genetic models in the study of alcoholism and substance abuse mechanisms

1993 • 27 citations

Selective breeding, congenic strains, and other classical genetic approaches to the analysis of alcohol-related polygenic pleiotropisms

1993 • 26 citations

Differential inhibition of synaptosomal accumulation of [3H]-monoamines by cocaine, tropacocaine and amphetamine in four inbred strains of mice

1989 • 21 citations

Tolerance to Ethanol Hypothermia in HOT and COLD Mice

1994 • 18 citations

Genetic factors in conditioned tolerance to the analgesic effects of etonitazene

1993 • 10 citations

Effects of electroconvulsive shock on the retention of cocaine-induced conditioning

1994 • 4 citations

Vulnerability to Substance Abuse

2010 • 4 citations