An in vivo study of the radioprotective effect of diethyldithiocarbamate (DDC)

A simplified method of evaluating dose-effect experiments.

1948 • 7,047 citations

A Direct Measurement of the Radiation Sensitivity of Normal Mouse Bone Marrow Cells¹

2010 • 4,125 citations

A Direct Measurement of the Radiation Sensitivity of Normal Mouse Bone Marrow Cells

1961 • 3,579 citations

Quantitative comparison of toxicity of anticancer agents in mouse, rat, hamster, dog, monkey, and man.

1966 • 1,363 citations

Active versus passive absorption kinetics as the basis for selective protection of normal tissues by S-2-(3-aminopropylamino)-ethylphosphorothioic acid.

1980 • 300 citations

Selective inhibition of the nephrotoxicity of cis-dichlorodiammineplatinum(II) by WR-2721 without altering its antitumor properties.

1980 • 146 citations

Radioprotection of tumor and normal tissues by thiophosphate compounds

1973 • 136 citations

Differential protection against cytotoxic chemotherapeutic effects on bone marrow CFUs by Wr-2721.

1981 • 105 citations

Treatment of tumours with the combination of WR-2721 and cis-dichlorodiammineplatinum (II) or cyclophosphamide

1980 • 103 citations

Rationale for initial clinical trials and future development of radioprotectors.

1980 • 73 citations

Prediction of the Effective Radioprotective Dose of WR-2721 in Humans through an Interspecies Tissue Distribution Study

1976 • 68 citations

Clinical trials of WR-2721 with radiation therapy

1982 • 64 citations

Interactions of disulfiram and diethyldithiocarbamate with serum proteins studied by means of a gel-filtration technique

1965 • 60 citations

Distribution and chemical forms of diethyldithiocarbamate and tetraethylthiuram disulphide (disulfiram) in mice in relation to radioprotection

1966 • 58 citations

In vivo and in vitro effects of thiuram disulfides and dithiocarbamates on hepatic microsomal drug metabolism in the rat*1

1979 • 57 citations

Metabolic balance studies in hepatolenticular degeneration treated with diethyldithiocarbamate

1963 • 57 citations

Direct action of a leukemogenic virus on the thymus.

1966 • 42 citations

The treatment of acute nickel carbonyl poisoning with sodium diethyldithiocarbamate.

1971 • 41 citations

Phase I clinical trials of WR-2721 with alkylating agent chemotherapy

1982 • 28 citations

Modification of the sensitivity and repair of potentially lethal damage by diethyldithiocarbamate during and following exposure of plateau-phase cultures of mammalian cells to radiation and cis-diamminedichloroplatinum(II).

1982 • 24 citations

Colony-forming units and survival of irradiated mice treated with AET or endotoxin.

1969 • 22 citations

The protective action of dithiocarbamates against the lethal effects of x-irradiation in mice.

1956 • 18 citations

Radioactive and Nonradioactive Methods for the In Vivo Determination of Disulfiram, Diethyldithiocarbamate, and Diethyldithiocarbamate‐Methyl Ester

1978 • 16 citations

Colony-Forming Units and Survival of Irradiated Mice Treated with AET or Endotoxin

1969 • 12 citations

Absorption, elimination and duration of action of diethyldithiocarbamate in animals [proceedings].

1976 • 1 citations