Function of the pancreatic B-cell during the development of hyperglycaemia in mice homozygous for the mutations ?diabetes? (db) and ?Misty? (m)

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Amino Acid Metabolism in Mammalian Cell Cultures

1959 • 4,025 citations

Diabetes, a New Mutation in the Mouse

1966 • 966 citations

The Maintenance of Human Normal Cells and Tumor Cells in Continuous Culture: I. Preliminary Report: Cultivation of Mesoblastic Tumors and Normal Tissue and Notes on Methods of Cultivation

1936 • 598 citations

The influence of genetic background on the expression of the obese (ob) gene in the mouse

1973 • 387 citations

Studies with the mutation, diabetes, in the mouse

1967 • 317 citations

Potassium ions and the secretion of insulin by islets of Langerhans incubated in vitro

1968 • 301 citations

Labelled proteins in tracer studies

1967 • 263 citations

The influence of genetic background on expression of mutations at the diabetes locus in the mouse. I. C57BL/KsJ and C57BL/6J strains

1972 • 260 citations

A Methodological Study of the Enzymatic Determination of Glucose in Blood

1963 • 190 citations

Insulin Biosynthesis

1972 • 137 citations

Studies on the secretion of newly synthesized proinsulin and insulin from isolated rat islets of langerhans

1972 • 102 citations

Studies in the diabetic mutant mouse: II. Electron microscopy of pancreatic islets

1970 • 93 citations

Simple Method for in Vitro Metabolic Studies Using Small Volumes of Tissue and Medium

1963 • 89 citations

Studies in the diabetic mutant mouse: I. Light microscopy and radioautography of pancreatic islets

1970 • 88 citations

INFLUENCE OF THE MUTATION "DIABETES" ON INSULIN RELEASE AND ISLET MORPHOLOGY IN MICE OF DIFFERENT GENETIC BACKGROUNDS

1974 • 83 citations

The secretion of newly synthesized insulin in vitro

1967 • 79 citations

Effects of glucose concentration on incorporation of [3H]leucine into insulin using isolated mammalian islets of Langerhans

1966 • 72 citations

Anti-Insulin Serum Coupled to Sepharose 4B as a Tool for the Investigation of Insulin Biosynthesis in the B-Cells of Obese Hyperglycemic Mice

1975 • 60 citations

Immunological reactivity of insulin to sepharose coupled with insulin-antibody—Its use for the extraction of insulin from serum

1970 • 58 citations

Pathogenesis of diabetes mellitus

1969 • 52 citations

Studies in the diabetic mutant mouse: IV. DBM, a modified diabetic mutant produced by outcrossing of the original strain

1970 • 26 citations

Effects of diet on pancreatic beta cell replication in mice with hereditary diabetes

1971 • 25 citations

Kinetics of Immunoreactive Insulin Release in Obese Hyperglycemic Laboratory Rodents*

1973 • 20 citations

The pathogenesis of diabetes mellitus. Possible usefulness of spontaneous hyperglycemic syndromes in animals.

1970 • 14 citations

Factors of importance for the etiology of obesity in mice.

1967 • 11 citations

Experimental and Spontaneous Diabetes in Animals: What is Their Relevance to Human Diabetes Mellitus?

1971 • 10 citations

Insulin Biosynthesis in Experimental Hereditary Diabetes

1971 • 9 citations

Disappearance of Serum Insulin in Obese-Hyperglycemic Mice

1970 • 3 citations