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The pharmacology of the behavioral and hypothermic responses of rats to 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT)

Data up to Jan 2025

Published1987
Citations197
References24

Total Citations Per Year

Abstract

References (24)

8-Hydroxy-2-(di-n-propylamino)-tetralin discriminates between subtypes of the 5-HT1 recognition site

1983 • 869 citations

Identity of inhibitory presynaptic 5-hydroxytryptamine (5-HT) autoreceptors in the rat brain cortex with 5-HT1B binding sites

1986 • 686 citations

The involvement of subtypes of the 5-HT1 receptor and of catecholaminergic systems in the behavioural response to 8-hydroxy-2-(di-n-Propylamino) tetralin in the rat

1984 • 678 citations

Two Distinct Central Serotonin Receptors with Different Physiological Functions

1981 • 640 citations

8-hydroxy-2-(di-n-propylamino)tetralin, 8-OH-DPAT, a potent and selective simplified ergot congener with central 5-HT-receptor stimulating activity

1982 • 517 citations

Presynaptic 5-HT autoreceptors on serotonergic cell bodies and/or dendrites but not terminals are of the 5-HT1A subtype

1985 • 383 citations

A behavioural and biochemical study in mice and rats of putative selective agonists and antagonists for 5‐HT1 and 5‐HT2 receptors

1985 • 378 citations

5-HT and anxiety

1984 • 325 citations

Determination of selective and nonselective compounds for the 5-HT 1A and 5-HT 1B receptor subtypes in rat frontal cortex.

1984 • 324 citations

Direct evidence for an interaction of β-adrenergic blockers with the 5-HT receptor

1977 • 275 citations

The pharmacology of the hypothermic response in mice to 8-hydroxy-2-(DI-n-propylamino)tetralin (8-OH-DPAT)

1985 • 254 citations

Anticonflict effect of the putative serotonin receptor agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT)

1984 • 221 citations

THE EFFECTS OF PUTATIVE 5‐HYDROXYTRYPTAMINE ANTAGONISTS ON THE BEHAVIOUR PRODUCED BY ADMINISTRATION OF TRANYLCYPROMINE AND L‐TRYPTOPHAN OR TRANYLCYPROMINE AND L‐DOPA TO RATS

1978 • 152 citations

Attenuation by electroconvulsive shock and antidepressant drugs of the 5-HT1A receptor-mediated hypothermia and serotonin syndrome produced by 8-OH-DPAT in the rat

1987 • 122 citations

Neuropharmacology of serotonin

1986 • 116 citations

β-Adrenoceptor blocking agents recognize a subpopulation of serotonin receptors in brain

1985 • 115 citations

Intracerebroventricular administration of 5,7-dihydroxytryptamine to mice increases both head-twitch response and the number of cortical 5-HT2 receptors

1985 • 107 citations

The enhancement by lithium of the 5-HT1A mediated serotonin syndrome produced by 8-OH-DPAT in the rat: evidence for a post-synaptic mechanism

1986 • 96 citations

The serotonin autoreceptor: Antagonism by quipazine

1982 • 71 citations

Quipazine-induced head-twitch in mice

1977 • 67 citations

Down-regulation of β-adrenoceptors in rat cortex by repeated administration of desipramine, electroconvulsive shock and clenbuterol requires 5-HT neurones but not 5-HT

1985 • 65 citations

β‐ADRENOCEPTOR AGONISTS ENHANCE 5‐HYDROXYTRYPTAMINE‐MEDIATED BEHAVIOURAL RESPONSES

1982 • 60 citations

8-OH-DPAT: an enigmatic centrally active 5-HT agonist

1984 • 11 citations

The β2-adrenoceptor agonists clenbuterol and salbutamol enhance the hypothermic action of 8-hydroxy-2-(di-n-propylamino)tetralin (8-oh-dpat) in mice by a central mechanism

1986 • 10 citations

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