Orientation of the LexA DNA-binding motif on operator DNA as inferred from cysteine-mediated phenyl azide crosslinking.

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Mutagenesis and inducible responses to deoxyribonucleic acid damage in Escherichia coli

1984 • 1,608 citations

The SOS regulatory system of Escherichia coli

1982 • 1,491 citations

DNA RECOGNITION BY PROTEINS WITH THE HELIX-TURN-HELIX MOTIF

1990 • 580 citations

Structure of the Lambda Complex at 2.5 Å Resolution: Details of the Repressor-Operator Interactions

1988 • 500 citations

Mechanism of action of the lexA gene product.

1981 • 424 citations

Mechanism of specific LexA cleavage: Autodigestion and the role of RecA coprotease

1991 • 339 citations

Sequence-specific binding and photocrosslinking of alpha and beta oligodeoxynucleotides to the major groove of DNA via triple-helix formation.

1988 • 216 citations

Systematic method for the detection of potential λ Cro-like DNA-binding regions in proteins

1987 • 191 citations

Dimerization of a Specific DNA-Binding Protein on the DNA

1992 • 138 citations

Synthesis of a Sequence-Specific DNA-Cleaving Peptide

1987 • 134 citations

Nucleotide sequence binding specificity of the LexA repressor of Escherichia coli K-12

1985 • 127 citations

Complex of lac repressor headpiece with a 14 base-pair lac operator fragment studied by two-dimensional nuclear magnetic resonance

1987 • 120 citations

DNA binding properties of the LexA repressor

1991 • 114 citations

Mutant lac repressors with new specificities hint at rules for protein--DNA recognition.

1990 • 111 citations

Large-scale purification, oligomerization equilibria, and specific interaction of the LexA repressor of Escherichia coli

1985 • 97 citations

Structural Motif of the GCN4 DNA Binding Domain Characterized by Affinity Cleaving

1990 • 91 citations

Double helices with parallel strands are formed by nuclease-resistant oligo-[α]-deoxynucleotides and oligo-[α]-deoxynucleotides covalently linked to an intercalating agent with complementary oligo-[β]-deoxynucleotides

1987 • 79 citations

Deletions within a hinge region of a specific DNA-binding protein.

1985 • 73 citations

Conversion of a helix-turn-helix motif sequence-specific DNA binding protein into a site-specific DNA cleavage agent.

1990 • 62 citations

In vitro binding of LexA repressor to DNA: evidence for the involvement of the amino-terminal domain.

1986 • 57 citations

Contacts between the LexA repressor-or its DNA-binding domain-and the backbone of the recA operator DNA.

1988 • 50 citations

Determination of the orientation of a DNA binding motif in a protein-DNA complex by photocrosslinking.

1992 • 47 citations

The carboxy‐terminal domain of the LexA repressor oligomerises essentially as the entire protein

1988 • 47 citations

Amino acids determining operator binding specificity in the helix-turn-helix motif of Tn10 Tet repressor.

1991 • 45 citations

Orientation of the putative recognition helix in the DNA-binding domain of Hin recombinase complexed with the Hix site

1990 • 42 citations

Genetic identification of the DNA binding domain of Escherichia coli LexA protein.

1992 • 35 citations

The amino-terminal domain of LexA repressor is alpha-helical but differs from canonical helix-turn-helix proteins: a two-dimensional 1H NMR study.

1989 • 32 citations

Interaction of a regulatory protein with a DNA target containing two overlapping binding sites

1991 • 29 citations

Genetic analysis of the LexA repressor: Isolation and characterization of LexA(Def) mutant proteins

1990 • 28 citations

Structural motif of the DNA binding domain of gamma delta-resolvase characterized by affinity cleaving.

1990 • 17 citations

Orientation of the Lac repressor DNA binding domain in complex with the leftlacoperator half site characterized by affinity cleaving

1991 • 12 citations

¹H-NMR Investigation of the Interaction of the Amino Terminal Domain of the LexA Repressor with a Synthetic Half-Operator

1991 • 11 citations