IgD and B Cell Differentiation

A Theory of Self-Nonself Discrimination

1970 • 1,700 citations

Fluorescence Activated Cell Sorting

1972 • 774 citations

IMMUNOGLOBULINS ON THE SURFACE OF LYMPHOCYTES

1971 • 665 citations

A Possible Precursor of Immunoglobulin Light Chains

1972 • 609 citations

IgG on Lymphocyte Surfaces; Technical Problems and the Significance of a Third Cell Population

1975 • 418 citations

CELL SURFACE IMMUNOGLOBULIN

1971 • 380 citations

Membrane receptors of lymphocytes

1978 • 341 citations

Immunoglobulin-Receptors Revisited

1975 • 302 citations

In vitro tolerance induction of neonatal murine B cells.

1976 • 281 citations

THE MECHANISM OF ANTIGENIC STIMULATION OF PRIMARY AND SECONDARY CLONAL PRECURSOR CELLS

1972 • 272 citations

ISOLATION AND PARTIAL CHARACTERIZATION OF LYMPHOCYTE SURFACE IMMUNOGLOBULINS

1972 • 258 citations

B lymphocyte differentiation induced by lipopolysaccharide. I. Generation of cells synthesizing four major immunoglobulin classes.

1975 • 250 citations

Differences in susceptibility of mature and immature mouse B lymphocytes to anti-immunoglobulin-induced immunoglobulin suppression in vitro. Possible implications for B-cell tolerance to self.

1975 • 228 citations

Structure and Function of γ Macroglobulins

1970 • 206 citations

British Optical Astronomy

1972 • 204 citations

Cell surface immunoglobulin. XI. The appearance of an IgD-like molecule on murine lymphoid cells during ontogeny.

1975 • 200 citations

IMMUNOGLOBULIN AND OTHER SURFACE ANTIGENS OF CELLS OF THE IMMUNE SYSTEM

1971 • 197 citations

Receptor-mediated inactivation of early B lymphocytes

1975 • 187 citations

OCCURRENCE OF SURFACE IgM, IgD, AND FREE LIGHT CHAINS ON HUMAN LYMPHOCYTES

1974 • 181 citations

Similar Idiotypic Specificity for the Membrane IgD and IgM of Human B Lymphocytes

1975 • 179 citations

Candidate for immunoglobulin D present on murine B lymphocytes

1974 • 170 citations

Inhibition of mitogenic stimulation of mouse lymphocytes by anti‐mouse immunoglobulin antibodies. I. Mode of action

1974 • 165 citations

IMMUNOGLOBULIN SYNTHESIS AND SECRETION

1970 • 163 citations

CELL SURFACE IMMUNOGLOBULIN

1974 • 139 citations

The Class of Surface Immunoglobulin on Virgin and Memory B Lymphocytes

1977 • 128 citations

Same Idiotypc of B‐Lymphocyte Membrane IgD and IgM. Formal Evidence for Monoclonality of Chronic Lymphocytic Leukemia Cells

1974 • 127 citations

Differential susceptibility of neonatal and adult murine spleen cells to in vitro induction of B-cell tolerance.

1976 • 123 citations

Proteases as mitogens

1974 • 119 citations

Independent Movement of IgD and IgM Molecules on the Surface of Individual Lymphocytes

1973 • 112 citations

IMMUNE RESPONSES IN VITRO

1972 • 111 citations

IgD and IgM on the membrane of lymphoid cells in macroglobulinemia. Evidence for identity of membrane IgD and IgM antibody activity in a case with anti‐IgG receptors

1974 • 110 citations

Stimulation of Mouse B Lymphocytes by Trypsin

1974 • 108 citations

Antigen-induced co-capping of IgM and IgD-like receptors on murine B cells.

1976 • 108 citations

Demonstration that IgG memory is carried by IgG‐bearing cells

1976 • 108 citations

B Lymphocyte Differentiation Induced by Lipopolysaccharide. III. Suppression of B Cell Maturation by Anti-Mouse Immunoglobulin Antibodies

1976 • 103 citations

B‐Lymphocyte Subpopulations in the Mouse

1975 • 92 citations

Surface immunoglobulins of lipopolysaccharide‐stimulated spleen cells The behaviour of IgM, IgD and IgG

1977 • 92 citations

IgD: A Major Immunoglobulin on the Surface of Lymphocytes from Patients with Chronic Lymphatic Leukemia

1974 • 91 citations

Ontogeny of lymphocyte subpopulations in human fetal liver.

1976 • 89 citations

B-cell tolerance. III. Effect of papain-mediated cleavage of cell surface IgD on tolerance susceptibility of murine B cells.

1977 • 84 citations

B-lymphocyte heterogeneity: ontogenetic development and organ distribution of B-lymphocyte populations defined by their density of surface immunoglobulin.

1976 • 83 citations

Preparation and characterisation of an antiserum to the mouse candidate for immunoglobulin D

1976 • 71 citations

B Lymphocyte Differentiation Induced by Lipopolysaccharide

1976 • 71 citations

B-cell tolerance. II. Trinitrophenyl human gamma globulin-induced tolerance in adult and neonatal murine B cells responsive to thymus- dependent and independent forms of the same hapten

1977 • 70 citations

IMMUNE RESPONSES IN VITRO

1972 • 69 citations

The relationship between surface immunoglobulin isotype and immune function of murine B lymphocytes II. Surface immunoglobulin isotopes on unprimed B cells in the spleen.

1977 • 69 citations

The relationship between surface immunoglobulin isotype and immune function of murine B lymphocytes. I. Surface immunoglobulin isotypes on primed B cells in the spleen.

1977 • 66 citations

Are immunoglobulins integral membrane proteins?

1975 • 64 citations

Cell surface immunoglobulin. XVI. Polypeptide chain structure of mouse IgM and IgD-like molecule.

1976 • 62 citations

Genetic polymorphism of IgD-like cell surface immunoglobulin in the mouse.

1976 • 62 citations

Loss of surface IgD by human B lymphocytes during polyclonal activation^*

1977 • 61 citations

Immunoglobulin Determinants on Mouse Lymphocytes

1971 • 61 citations

MITOGENIC ACTION OF TRYPSIN AND CHYMOTRYPSIN

1966 • 60 citations

Intracellular events underlying synthesis and secretion of immunoglobulin

1970 • 58 citations

Cell surface immunoglobulin. XX. Antibody responsiveness of subpopulations of B lymphocytes bearing different isotypes.

1977 • 57 citations

Structure and biologic functions of human IgD. XI. Identification and ontogeny of a rat lymphocyte immunoglobulin having antigenic cross-reactivity with human IgD.

1977 • 57 citations

B lymphocyte differentiation induced by lipopolysaccharide. II. Response of fetal lymphocytes.

1975 • 56 citations

MEMBRANE‐ASSOCIATED IMMUNOGLOBULIN DETERMINANTS ON BONE MARROW AND BLOOD LYMPHOCYTES IN THE PEDIATRIC AGE GROUP AND ON FETAL TISSUES

1975 • 55 citations

Induction of Unresponsiveness and Immunity in Newborn and Adult Mice with Pneumococcal Polysaccharide

1963 • 53 citations

Effect of Antigen Density on Complement-Mediated Lysis, T-Cell-Mediated Killing, and Antigenic Modulation<xref ref-type="fn" rid="fn2"><sup>2</sup></xref>

1974 • 49 citations

The class of surface immunoglobulin on cells carrying IgG memory in rat thoracic duct lymph: the size of the subpopulation mediating IgG memory.

1976 • 49 citations

Surface and Intracellular Markers of Mouse Mesenteric and Peripheral Lymph Node and Peyer's Patch Cells

1974 • 48 citations

Lymphocyte Surface IgD and IgM in Non-Human Primates

1976 • 46 citations

Cell surface immunoglobulin. XVIII. Functional differences of B lymphocytes bearing different surface immunoglobulin isotypes.

1976 • 46 citations

The synthesis and secretion of gamma-globulin by lymph node cells. 3. The slow acquisition of the carbohydrate moiety of gamma-globulin and its relationship to secretion.

1968 • 42 citations

RESTRICTION OF GENE EXPRESSION IN B LYMPHOCYTES AND THEIR PROGENY

1974 • 42 citations

Ontogeny of mouse B lymphocytes and inactivation by antigen of early B lymphocytes.

1976 • 41 citations

CELL SURFACE IMMUNOGLOBULIN

1974 • 41 citations

A Developmental Approach to the Biological Basis for Antibody Diversity

1972 • 41 citations

Lack of neonatal susceptibility to induction of tolerance by polysaccharide antigens

1976 • 41 citations

B Lymphocyte Differentiation Induced by Lipopolysaccharide

1975 • 39 citations

Isologous IgG‐Induced Immunologic Tolerance to Haptens: A Model of Self Versus Non‐Self Recognition

1976 • 37 citations

Effect of Antigen Density on Complement-Mediated Lysis, T-Cell-Mediated Killing, and Antigenic Modulation

1974 • 32 citations

Cell Surface Immunoglobulin. XIII. Distribution of IgM and IgD-Like Molecules on Small and Large Cells of Mouse Spleen

1975 • 32 citations

Density differences between membrane and secreted immunoglobulins of murine splenocytes

1977 • 30 citations

Immunoglobulins M and D as antigen‐binding receptors on the same cell, with shared specificity

1976 • 30 citations

Allotypes of IgM and IgD Receptors in the Mouse: A Probe for Lymphocyte Differentiation

1978 • 29 citations

Cell surface immunoglobulin. XIX. Susceptibility of IgD and IgM on murine splenocytes to cleavage by papain.

1976 • 29 citations

Cell surface immunoglobulin. XV. The presence of IgM and an IgD-like molecule on the same cell in murine lymphoid tissue

1976 • 25 citations

Cell Surface Immunoglobulin. XXII. Reappearance of Surface IgM and IgD on Murine Splenocytes after Removal by Capping

1977 • 22 citations

Cell Surface Immunoglobulin. XIV. Synthesis, Surface Expression, and Secretion of Immunoglobulin by Peyer's Patch Cells in the Mouse

1975 • 21 citations

Immunoglobulin Receptors on Murine B Lymphocytes

1977 • 21 citations

In Vitro Induction of Specific Unresponsiveness against the 2,4,6-Trinitrophenyl Determinant: I. The Induction of Unresponsiveness

1974 • 14 citations

Glycosyl Transferases for Mouse IgG

1970 • 12 citations

In Vitro Induction of Specific Unresponsiveness Against the 2,4,6-Trinitrophenyl Determinant

1974 • 10 citations