Species differences in structure‐activity relationships of adenosine agonists and xanthine antagonists at brain A1 adenosine receptors

Adenosine receptors: targets for future drugs

1982 • 681 citations

Adenosine receptors in brain membranes: binding of N6-cyclohexyl[3H]adenosine and 1,3-diethyl-8-[3H]phenylxanthine.

1980 • 554 citations

1,3-Dialkyl-8-(p-sulfophenyl)xanthines: potent water-soluble antagonists for A1- and A2-adenosine receptors

1985 • 223 citations

Adenosine receptor binding: structure-activity analysis generates extremely potent xanthine antagonists.

1983 • 164 citations

Purines : pharmacology and physiological roles

1985 • 134 citations

Analogs of caffeine and theophylline: effect of structural alterations on affinity at adenosine receptors

1986 • 121 citations

Heterogeneity of adenosine A1 receptor binding in brain tissue.

1982 • 115 citations

Analogs of caffeine: Antagonists with selectivity for A2 adenosine receptors

1986 • 96 citations

[3H]xanthine amine congener of 1,3-dipropyl-8-phenylxanthine: an antagonist radioligand for adenosine receptors.

1986 • 85 citations

Definition of subclasses of adenosine receptors associated with adenylate cyclase: interaction of adenosine analogs with inhibitory A₁ receptors and stimulatory A₂ receptors

1987 • 64 citations

Functionalized congeners of adenosine: preparation of analogs with high affinity for A1-adenosine receptors

1985 • 60 citations

A functionalized congener approach to adenosine receptor antagonists: amino acid conjugates of 1,3-dipropylxanthine.

1986 • 58 citations

Dog coronary artery adenosine receptor. Structure of the N6-aryl subregion

1986 • 56 citations

Functionalized congeners of 1,3-dipropyl-8-phenylxanthine: Potent antagonists for adenosine receptors that modulate membrane adenylate cyclase in pheochromocytoma cells, platelets and fat cells

1986 • 53 citations

N6-Substituted N-alkyladenosine-5'-uronamides: bifunctional ligands having recognition groups for A1 and A2 adenosine receptors

1986 • 44 citations

Dog coronary artery adenosine receptor: structure of the N6-alkyl subregion

1985 • 41 citations

A [³H]amine congener of 1,3‐dipropyl‐8‐phenylxanthine

1986 • 37 citations

Analogs of 1,3-dipropyl-8-phenylxanthine: enhancement of selectivity at A1-adenosine receptors by aryl substituents

1986 • 34 citations

Adenosine receptors.

1985 • 26 citations

Inhibition by indomethacin of naloxone-precipitated opiate withdrawal contraction in isolated guinea pig myenteric plexus-longitudinal muscle preparation

1986 • 5 citations