The likeness of being: Phylogenetically conserved molecular mechanisms of growth cone guidance

Developmental mechanisms that generate precise patterns of neuronal connectivity

1993 • 1,435 citations

The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6

1994 • 1,346 citations

Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord

1994 • 1,311 citations

Collapsin: A protein in brain that induces the collapse and paralysis of neuronal growth cones

1993 • 1,146 citations

Inactivation of the N-CAM gene in mice results in size reduction of the olfactory bulb and deficits in spatial learning

1994 • 1,010 citations

The semaphorin genes encode a family of transmembrane and secreted growth cone guidance molecules

1993 • 930 citations

The unc-5, unc-6, and unc-40 genes guide circumferential migrations of pioneer axons and mesodermal cells on the epidermis in C. elegans

1990 • 909 citations

Chemotropic guidance of developing axons in the mammalian central nervous system

1988 • 681 citations

Mutations affecting growth cone guidance in drosophila: Genes necessary for guidance toward or away from the midline

1993 • 677 citations

Neuronal Chemotaxis: Chick Dorsal-Root Axons Turn Toward High Concentrations of Nerve Growth Factor

1979 • 522 citations

UNC-6, a laminin-related protein, guides cell and pioneer axon migrations in C. elegans

1992 • 503 citations

Genetic deletion of a neural cell adhesion molecule variant (N-CAM-180) produces distinct defects in the central nervous system

1993 • 476 citations

Genetic analysis of growth cone guidance in drosophila: Fasciclin II functions as a neuronal recognition molecule

1991 • 464 citations

UNC-5, a transmembrane protein with immunoglobulin and thrombospondin type 1 domains, guides cell and pioneer axon migrations in C. elegans

1992 • 404 citations

Drosophila neuroglian: A member of the immunoglobulin superfamily with extensive homology to the vertebrate neural adhesion molecule L1

1989 • 390 citations

Earliest sensory nerve fibres are guided to peripheral targets by attractants other than nerve growth factor

1983 • 356 citations

Collapse of growth cone structure on contact with specific neurites in culture

1987 • 284 citations

Genes necessary for directed axonal elongation or fasciculation in C. elegans

1992 • 245 citations

Signal transduction events underlying neurite outgrowth stimulated by cell adhesion molecules

1994 • 242 citations

Expression of the UNC-5 guidance receptor in the touch neurons of C. elegans steers their axons dorsally

1993 • 237 citations

Polysialic acid influences specific pathfinding by avian motoneurons

1992 • 229 citations

Orientation of commissural axons in vitro in response to a floor plate-derived chemoattractant

1990 • 227 citations

Chemorepulsion of axons in the developing mammalian central nervous system

1993 • 180 citations

The irregular chiasm C-roughest locus of Drosophila, which affects axonal projections and programmed cell death, encodes a novel immunoglobulin-like protein.

1993 • 174 citations

The selective inhibition of growth cone extension by specific neurites in culture

1986 • 126 citations

Ventral spinal cord inhibition of neurite outgrowth from embryonic rat dorsal root ganglia

1993 • 99 citations