Telomerase and cellular lifespan: Ending the debate?
Data up to Jan 2025
Total Citations Per Year
Abstract
References (18)
The serial cultivation of human diploid cell strains
1961 • 7,886 citations
The limited in vitro lifetime of human diploid cell strains
1965 • 5,595 citations
Extension of Life-Span by Introduction of Telomerase into Normal Human Cells
1998 • 4,845 citations
Telomere length predicts replicative capacity of human fibroblasts.
1992 • 2,209 citations
Telomere Shortening and Tumor Formation by Mouse Cells Lacking Telomerase RNA
1997 • 2,086 citations
Replicative life-span of cultivated human cells. Effects of donor's age, tissue, and genotype.
1970 • 1,002 citations
Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT
1997 • 946 citations
The relationship between in vitro cellular aging and in vivo human age.
1976 • 559 citations
Telomerase activity: A biomarker of cell proliferation, not malignant transformation
1997 • 240 citations
Cell aging in vivo and in vitro
1997 • 232 citations
Telomerase regulation during entry into the cell cycle in normal human T cells.
1996 • 206 citations
Telomerase activity in human endometrium
2003 • 195 citations
Chronologic and Physiologic Age Affect Replicative Life-Span of Fibroblasts from Diabetic, Prediabetic, and Normal Donors
1978 • 188 citations
Characteristics of an infinite life span diploid human fibroblast cell strain and a near-diploid strain arising from a clone of cells expressing a transfectedv-myc oncogene
1991 • 85 citations
Effect of temperature on the longevity of human fibroblasts in culture
1973 • 40 citations
The transformed (initiated) human cell phenotype: study of cultured skin fibroblasts from individuals predisposed to cancer
1988 • 15 citations
Human fibroblasts from cancer patients: lifespan and transformed phenotype in vitro and role of mesenchyme in vivo
1988 • 14 citations
Heritable Colonic Cancer Syndromes: Induction of Anchorage-Independence in Dermal Cultures Derived from Patients with Adenomatosis of the Colon and Rectum
1980 • 11 citations