Generation and maintenance of autoantigen-specific CD8+ T cell clones isolated from NOD mice

Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules

1991 • 2,447 citations

Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase

1990 • 1,955 citations

Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes

1993 • 1,087 citations

Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice

1993 • 962 citations

Empty MHC class I molecules come out in the cold

1990 • 933 citations

Stimulation of B-cell progenitors by cloned murine interleukin-7

1988 • 826 citations

Helper activity is required for the in vivo generation of cytotoxic T lymphocytes

1982 • 511 citations

The first external domain of the nonobese diabetic mouse class II I-A beta chain is unique.

1987 • 402 citations

B cell precursor growth-promoting activity. Purification and characterization of a growth factor active on lymphocyte precursors.

1988 • 379 citations

Antibodies to a 64,000 Mr human islet cell antigen precede the clinical onset of insulin-dependent diabetes.

1987 • 319 citations

The lymphoreticular system in triggering virus plus self-specific cytotoxic T cells: evidence for T help.

1978 • 268 citations

Analysis of cytokine gene expression during fetal thymic ontogeny using the polymerase chain reaction.

1991 • 175 citations

Differential Expression of GAD65 and GAD67 in Human, Rat, and Mouse Pancreatic Islets

1993 • 165 citations

Murine thymocytes proliferate in direct response to interleukin-7

1989 • 157 citations

Interleukin 7: effects on early events in lymphopoiesis

1989 • 140 citations

Cooperation between cytotoxic and helper T lymphocytes in protection against lethal Sendai virus infection. Protection by T cells is MHC-restricted and MHC-regulated; a model for MHC-disease associations.

1986 • 139 citations

Distinct Ir genes for helper and killer cells in the cytotoxic response to H-Y antigen.

1979 • 122 citations

IL-7 promotes thymocyte proliferation and maintains immunocompetent thymocytes bearing alpha beta or gamma delta T-cell receptors in vitro: synergism with IL-2.

1989 • 119 citations

Interleukin‐7 expression during mouse thymus development

1992 • 112 citations

Class I MHC molecules rather than other mouse genes dictate influenza epitope recognition by cytotoxic T cells

1987 • 99 citations

T helper epitopes enhance the cytotoxic response of mice immunized with MHC class I-restricted malaria peptides

1992 • 97 citations

Differential Expression of Glutamic Acid Decarboxylase in Rat and Human Islets

1993 • 97 citations

Cooperation between Helper T Cells and Cytotoxic T Lymphocyte Precursors

1988 • 86 citations

Interleukin 7 (murine pre‐B cell growth factor/lymphopoietin 1) stimulates thymocyte growth: regulation by transforming growth factor beta

1989 • 66 citations

Differential expression of GAD65 and GAD67 in human, rat, and mouse pancreatic islets

1993 • 52 citations

Different rules govern help for cytotoxic T cells and B cells

1978 • 48 citations

Synergism of interleukin 7 with the thymocyte growth factors interleukin 2, interleukin 6, and tumor necrosis factor α in the induction of thymocyte proliferation

1990 • 32 citations

Differential expression of glutamic acid decarboxylase in rat and human islets

1993 • 31 citations

Human autoantibodies react with glutamic acid decarboxylase antigen in human and rat but not in mouse pancreatic islets

1993 • 29 citations

Helper effects required during in vivo priming for a cytolytic response to the H-Y antigen in nonresponder mice.

1985 • 22 citations

T–T cell collaboration during in vivo responses to antigens coded by the peripheral and central region of the MHC

1976 • 14 citations

THE IN VIVO CYTOTOXIC T CELL RESPONSE TO ALLOANTIGEN REQUIRES A Lyt-1+ HELPER T LYMPHOCYTE

1981 • 7 citations