5'-O-Monophosphoryladenylyl(2' goes to 5')adenylyl(2' goes to 5')adenosine is an antagonist of the action of 5'-O-triphosphoryladenylyl-(2' goes to 5')adenylyl(2' goes to 5')adenosine and double-stranded RNA.

pppA2'p5'A2'p5'A: an inhibitor of protein synthesis synthesized with an enzyme fraction from interferon-treated cells.

1978 • 787 citations

Inhibition of cell-free protein synthesis by pppA2′ p5′ A2′ p5′ A: a novel oligonucleotide synthesized by interferon-treated L cell extracts

1978 • 435 citations

Interferon-induced enzymatic activities and their role in the antiviral state

1979 • 392 citations

Synthesis of low molecular weight inhibitor of protein synthesis with enzyme from interferon-treated cells

1977 • 367 citations

Interferon, double-stranded RNA, and protein phosphorylation.

1976 • 328 citations

Interferon action—sequence specificity of the ppp(A2′p)nA-dependent ribonuclease

1981 • 321 citations

Interferon action may be mediated by activation of a nuclease by pppA2′p5′A2′p5′A

1978 • 310 citations

The Regulation of Initiation of Mammalian Protein Synthesis

1981 • 266 citations

2-5A synthetase: assay, distribution and variation with growth or hormone status

1979 • 260 citations

Natural occurrence of 2-5A in interferon-treated EMC virus-infected L cells

1979 • 245 citations

Radioimmune, radiobinding and HPLC analysis of 2-5A and related oligonucleotides from intact cells

1980 • 242 citations

Specific phosphorylation in vitro of a protein associated with ribosomes of interferon‐treated mouse L cells

1976 • 238 citations

Interferon action: two distinct pathways for inhibition of protein synthesis by double-stranded RNA.

1978 • 216 citations

An interferon-induced phosphodiesterase degrading (2'-5') oligoisoadenylate and the C-C-A terminus of tRNA.

1979 • 183 citations

Increased sensitivity of cell-free protein synthesis to double-stranded RNA after interferon treatment

1974 • 179 citations

Regulation of lymphocyte mitogenesis by (2′–5′) oligo-isoadenylate

1979 • 148 citations

Interferon, double-stranded RNA, and RNA degradation: activation of an endonuclease by (2'-5')An.

1979 • 140 citations

Synthesis and Breakdown of pppA2′p5′A2′p5′A and Transient Inhibition of Protein Synthesis in Extracts from Interferon‐Treated and Control Cells

1978 • 140 citations

Enzymic Synthesis, Characterisation and Nuclear‐Magnetic‐Resonance Spectra of pppA2′p5′A2′p5′A and Related Oligonucleotides: Comparison with Chemically Synthesised Material

1979 • 101 citations

Increased levels of (2'-5')oligo(A) polymerase activity in human lymphoblastoid cells treated with glucocorticoids.

1980 • 91 citations

Interferon, double-stranded RNA, and RNA degradation. Isolation of homogeneous pppA(2'p5'A)n-1 synthetase from Ehrlich ascites tumor cells.

1980 • 86 citations

Interferon-induced inhibition of protein synthesis in L-cell extracts: an ATP-dependent step in the activation of an inhibitor by double-stranded RNA.

1976 • 78 citations

2‘,5‘-Oligoadenylate synthetase activity in lymphocytes from normal mouse.

1979 • 71 citations

Synthesis of (2'-5')(A)n from ATP. Characteristics of the reaction catalyzed by (2'-5')(A)n synthetase purified from mouse Ehrlich ascites tumor cells treated with interferon.

1980 • 64 citations

2′5′oligo(A) polymerase activity in serum of mice infected with EMC virus or treated with interferon

1980 • 56 citations

Mechanism of interferon action Properties of an interferon-mediated ribonucleolytic activity from mouse L9z9 cells

1978 • 56 citations

Intracellular Events in Interferon-Treated Cells

1979 • 53 citations

Are double-stranded RNA-directed inhibition of protein synthesis in interferon-treated cells and interferon induction related phenomena?

1979 • 48 citations

Nuclease activation by double-stranded RNA and by 2′,5′-oligoadenylate in extracts of interferon-treated chick cells

1979 • 44 citations

Mechanism of interferon action. Kinetics of interferon action in mouse L929 cells: Phosphorylation of protein synthesis initiation factor eIF-2 and ribosome-associated protein P1

1979 • 41 citations

Site-specific phosphorylation of the α subunit of eukaryotic initiation factor eIF-2 by the heme-regulated and double-stranded RNA-activated eIF-2α kinases from rabbit reticulocyte lysates

1980 • 40 citations

Differential Effects of Two Interferon‐Induced Translational Inhibitors on Initiation of Protein Synthesis

1979 • 37 citations

Induction of 2',5'-oligoadenylate synthetase and interferon in mouse trigeminal ganglia infected with herpes simplex virus

1980 • 37 citations

Double-stranded RNA inhibits a phosphoprotein phosphatase present in interferon-treated cells.

1980 • 35 citations

An interferon-induced cellular enzyme is incorporated into virions

1980 • 28 citations

Oligo(2′–5′)adenylate synthetase in human lymphoblastoid cells

1980 • 16 citations

Comparison of Interferon Action in Interferon Resistant and Sensitive L1210 Cells

1978 • 15 citations

Interferon-induced (2'-5')-oligoadenylate synthetase: adsorption to and assay on adenosine 2',5'-diphosphate-Sepharose

1980 • 15 citations