Selective enrichment of specific DNA, cDNA and RNA sequences using biotinylated probes, avidin and copper-chelate agarose

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Metal chelate affinity chromatography, a new approach to protein fractionation

1975 • 2,050 citations

Avidin

1975 • 1,425 citations

Detection of viral genomes in cultured cells and paraffin-embedded tissue sections using biotin-labeled hybridization probes

1983 • 707 citations

Non-radioactive hybridization probes prepared by the chemical labelling of DNA and RNA with a novel reagent, photobiotin

1985 • 526 citations

Specific cloning of DNA fragments absent from the DNA of a male patient with an X chromosome deletion.

1985 • 455 citations

Mouse beta 2-microglobulin cDNA clones: a screening procedure for cDNA clones corresponding to rare mRNAs.

1981 • 320 citations

Developmental gene regulation in Aspergillus nidulans

1980 • 253 citations

Molecular cloning and selection of genes regulated in aspergillus development

1980 • 190 citations

Induction of erythroid differentiation in vitro by purines and purine analogues

1976 • 186 citations

Molecular cloning and nucleotide sequence of the streptavidin gene

1986 • 186 citations

Cell-type-specific cDNA probes and the murine I region: the localization and orientation of Ad alpha.

1984 • 167 citations

DNA Hybridization Technique for the Detection of Neisseria gonorrhoeae in Men with Urethritis

1983 • 126 citations

Analysis of erythropoeisis at the molecular level

1976 • 122 citations

Purification of low-abundance messenger RNAs from rat liver by polysome immunoadsorption.

1982 • 119 citations

cDNA clones for the heavy chain of HLA-DR antigens obtained after immunopurification of polysomes by monoclonal antibody.

1982 • 107 citations

Multihormonal induction of hepatic α _2u -globulin mRNA as measured by hybridization to complementary DNA

1977 • 92 citations

An immunochemical method for mRNA purification. Application to messenger RNA encoding trypanosome variable surface antigen.

1981 • 84 citations

Isolation of lactoferrin from human milk by metal‐chelate affinity chromatography

1977 • 83 citations

Deoxyribonucleic Acid Homologies Among Species of the GenusNeisseria

1967 • 79 citations

Affinity chromatography on columns containing nucleic acids

1978 • 29 citations

Fractionation of granule proteins of granulocytes by copper chelate chromatography

1979 • 28 citations

Regulation of a group of abundant mRNA sequences during friend cell differentiation

1979 • 22 citations