Evaluation of protein models by atomic solvation preference

Dictionary of protein secondary structure: Pattern recognition of hydrogen‐bonded and geometrical features

1983 • 14,802 citations

The protein data bank: A computer-based archival file for macromolecular structures

1977 • 8,627 citations

The interpretation of protein structures: Estimation of static accessibility

1971 • 5,771 citations

Some Factors in the Interpretation of Protein Denaturation

1959 • 4,817 citations

WHAT IF: A molecular modeling and drug design program

1990 • 3,484 citations

The Anatomy and Taxonomy of Protein Structure

1981 • 3,376 citations

A Method to Identify Protein Sequences That Fold into a Known Three-Dimensional Structure

1991 • 2,629 citations

Solvation energy in protein folding and binding

1986 • 1,853 citations

A simplified representation of protein conformations for rapid simulation of protein folding

1976 • 1,099 citations

Selection of representative protein data sets

1992 • 823 citations

Accessible surface areas as a measure of the thermodynamic parameters of hydration of peptides.

1987 • 737 citations

Crystal structure of yeast cytochrome c peroxidase refined at 1.7-A resolution.

1984 • 714 citations

Hydrophobic parameters π of amino-acid side chains from the partitioning of N-acetyl-amino-acid amides.

1983 • 705 citations

Surface and inside volumes in globular proteins

1979 • 704 citations

Determination of the three-dimensional solution structure of the C-terminal domain of cellobiohydrolase I from Trichoderma reesei. A study using nuclear magnetic resonance and hybrid distance geometry-dynamical simulated annealing

1989 • 513 citations

Determinants of a protein fold

1987 • 498 citations

Structure of bovine pancreatic phospholipase A2 at 1.7 Å resolution

1981 • 429 citations

Structure of tyrosyl-tRNA synthetase refined at 2.3 Å resolution

1989 • 375 citations

Binding of chloromethyl ketone substrate analogs to crystalline papain

1976 • 352 citations

Database algorithm for generating protein backbone and side-chain co-ordinates from a Cα trace

1991 • 324 citations

THE CLASSIFICATION AND ORIGINS OF PROTEIN FOLDING PATTERNS

1990 • 308 citations

Identification of native protein folds amongst a large number of incorrect models

1990 • 305 citations

An analysis of incorrectly folded protein models

1984 • 282 citations

X-ray analysis (1. 4-Å resolution) of avian pancreatic polypeptide: Small globular protein hormone

1981 • 279 citations

Refined structure of cytochrome c3 at 1.8 Å resolution

1984 • 276 citations

Molecular structure of a dimer composed of the variable portions of the Bence-Jones protein REI refined at 2.0-Å resolution

1975 • 266 citations

Crystal and molecular structure of the serine proteinase inhibitor CI-2 from barley seeds

1987 • 260 citations

Two-Angstrom Crystal Structure of Oxidized Chromatium High Potential Iron Protein

1974 • 242 citations

Detection of native‐like models for amino acid sequences of unknown three‐dimensional structure in a data base of known protein conformations

1992 • 239 citations

Structure of porcine pancreatic phospholipase A2 at 2·6resolution and comparison with bovine phospholipase A2

1983 • 233 citations

Crystal and molecular structures of native and CTP-liganded aspartate carbamoyltransferase from Escherichia coli

1982 • 227 citations

Structure of the semiquinone form of flavodoxin from Clostridium MP

1977 • 221 citations

Criteria that discriminate between native proteins and incorrectly folded models

1988 • 197 citations

Structure of bovine liver rhodanese

1978 • 187 citations

Empirical solvation models can be used to differentiate native from near‐native conformations of bovine pancreatic trypsin inhibitor

1991 • 185 citations

Crystallographic refinement of rubredoxin at 1·2 Å resolution

1980 • 178 citations

Complex of N-phosphonacetyl-l-aspartate with aspartate carbamoyltransferase

1988 • 175 citations

Secondary structure‐based profiles: Use of structure‐conserving scoring tables in searching protein sequence databases for structural similarities

1991 • 170 citations

Ribonuclease-A: least-squares refinement of the structure at 1.45 Å resolution

1982 • 163 citations

Structure of Peptococcus aerogenes ferredoxin. Refinement at 2 A resolution.

1976 • 163 citations

Protein folding: Evaluation of some simple rules for the assembly of helices into tertiary structures with myoglobin as an example

1979 • 155 citations

Refinement of the 7 Fe ferredoxin from Azotobacter vinelandii at 1.9 Å resolution

1989 • 147 citations

Analysis and prediction of the packing of α-helices against a β-sheet in the tertiary structure of globular proteins

1982 • 141 citations

A search for the most stable folds of protein chains

1991 • 135 citations

Novel method for the rapid evaluation of packing in protein structures

1990 • 130 citations

Crystallographic structural analysis of phosphoramidates as inhibitors and transition-state analogs of thermolysin

1986 • 110 citations

Polarity as a criterion in protein design

1989 • 110 citations

Structure of the l-arabinose-binding protein from Escherichia coli at 2.4 Å resolution

1981 • 104 citations

Iron-sulfur clusters and protein structure of Azotobacter ferredoxin at 2·0 Å resolution

1982 • 104 citations

Structure of variant-3 scorpion neurotoxin from Centruroides sculpturatus ewing, refined at 1·8 Å resolution

1983 • 103 citations

Protein model structure evaluation using the solvation free energy of folding.

1990 • 102 citations

Identification of protein folds: Matching hydrophobicity patterns of sequence sets with solvent accessibility patterns of known structures

1990 • 99 citations

Free energies of hydration of solute molecules. 4. Revised treatment of the hydration shell model

1988 • 96 citations

A 2.0-Å structure of the blue copper protein (cupredoxin) from Alcaligenes faecalis S-6

1989 • 96 citations

Structure of phage 434 cro protein at 2.35 Å resolution

1989 • 76 citations

Excluded volume approximation to protein-solvent interaction. The solvent contact model

1990 • 69 citations

Buried surface area, conformational entropy, and protein stability

1984 • 59 citations

Correctly folded proteins make twice as many hydrophobic contacts

1987 • 48 citations

Adjustment of restraints in the refinement of methemerythrin and azidomethemerythrin at 2.0 Å resolution

1983 • 47 citations

Van der Waals volume fragmental constants

1985 • 45 citations

Volume of the intersection of three spheres of unequal size: a simplified formula

1987 • 43 citations

The hydrophobic effect

1991 • 42 citations

Surface area of the intersection of three spheres with unequal radii A simplified analytical formula

1988 • 35 citations

Apomyoglobin as a molecular recognition surface: expression, reconstitution and crystallization of recombinant porcine myoglobin in Escherichia coli

1988 • 26 citations

Solvent Accessibility and Microenvironment in a Bacterial Protein Proteinase Inhibitor SSI (Streptomyces Subtilisin Inhibitor)1

1980 • 25 citations

Accessible surface areas as a measure of the thermodynamic parameters of hydration of peptides

1987 • 14 citations