Heterogeneity in antigenic expression and radiosensitivity in human colon carcinoma cell lines

ACTION OF X-RAYS ON MAMMALIAN CELLS

1956 • 1,660 citations

Colorectal carcinoma antigens detected by hybridoma antibodies

1979 • 1,342 citations

New Human Tumor Cell Lines

1975 • 974 citations

Classification of human colorectal adenocarcinoma cell lines.

1976 • 943 citations

Absence of HeLa Cell Contamination in 169 Cell Lines Derived From Human Tumors2

1977 • 648 citations

Intrinsic radiosensitivity of human cell lines is correlated with radioresponsiveness of human tumors: Analysis of 101 published survival curves

1985 • 488 citations

The radioresponsiveness of human tumours and the initial slope ofthe cell survival curve

1984 • 472 citations

Estimates of the worldwide frequency of twelve major cancers.

1984 • 434 citations

Human colonic adenocarcinoma cells

1976 • 375 citations

Radiation biology in cancer research

1978 • 340 citations

Cell lines from human colon carcinoma with unusual cell products, double minutes, and homogeneously staining regions.

1979 • 252 citations

Monoclonal Antibodies against Gastrointestinal Tumour-Associated Antigens Isolated as Monosialogangliosides

1983 • 183 citations

Preoperative irradiation for unresectable rectal and rectosigmoid carcinomas

1983 • 160 citations

A Colon Cancer Cell Line (LIM1215) Derived From a Patient With Inherited Nonpolyposis Colorectal Cancer<xref ref-type="fn" rid="FN1">2</xref>

1985 • 159 citations

Penetration and binding of radiolabeled anti-carcinoembryonic antigen monoclonal antibodies and their antigen binding fragments in human colon multicellular tumor spheroids.

1987 • 150 citations

Dose-response relationship for radiation therapy of recurrent, residual, and primarily inoperable colorectal cancer

1984 • 133 citations

Differential responses to x-irradiation of subpopulations of two heterogeneous human carcinomas in vitro.

1982 • 104 citations

Clinical applications of carcinoembryonic antigen.

1988 • 95 citations

Radioimmunotherapy of human colonic cancer xenografts with 90Y labeled monoclonal antibodies to carcinoembryonic antigen.

1988 • 79 citations

Targeting of cancer with radiolabeled antibodies. Prospects for imaging and therapy.

1988 • 77 citations

Improved tumor localization with increasing dose of indium-111-labeled anti-carcinoembryonic antigen monoclonal antibody ZCE-025 in metastatic colorectal cancer.

1988 • 73 citations

Characterization of human colon carcinoma cell lines isolated from a single primary tumour

1983 • 72 citations

Radioimmunotherapy of human colon carcinoma by ¹³¹I‐labelled monoclonal anti‐cea antibodies in a nude mouse model

1988 • 72 citations

Tumor localization of CEA‐containing human tumors in nude mice by means of monoclonal anti‐CEA antibodies

1982 • 71 citations

Radioimmunotherapy of the GW-39 human colonic tumor xenograft with 131I-labeled murine monoclonal antibody to carcinoembryonic antigen.

1987 • 67 citations

Colorectal tumors: scintigraphy with In-111 anti-CEA monoclonal antibody and correlation with surgical, histopathologic, and immunohistochemical findings.

1988 • 62 citations

Specificities and binding properties of eight monoclonal antibodies against carcinoembryonic antigen

1982 • 61 citations

Carcinoembryonic antigen and carbohydrate antigen 19-9 levels of peripheral and draining venous blood in colorectal cancer patients correlation with histopathologic and immunohistochemical variables

1988 • 44 citations

Tumour Markers in Colorectal Cancer

1988 • 42 citations

Significance of a fall in serum CEA concentration in patients treated with cytotoxic chemotherapy for disseminated colorectal cancer.

1987 • 41 citations

Impact of radiolabeled antibody imaging on management of colon cancer

1989 • 37 citations

Preoperative Irradiation of Primarily Non-Resectable Adenocarcinoma of the Rectum and Rectosigmoid

1985 • 35 citations

Irradiation and surgery for primarily inoperable rectal adenocarcinoma

1980 • 26 citations

Selenite-Induced Variation in Glutathione Peroxidase Activity of Three Mammalian Cell Lines: No Effect on Radiation-Induced Cell Killing or DNA Strand Breakage

1989 • 25 citations

Antigenic heterogeneity and individuality in adenocarcinomas of the rectum and their secondaries

1987 • 24 citations

Homogeneous penetration but heterogeneous binding of antibodies to carcinoembryonic antigen in human colon carcinoma HT-29 spheroids

1989 • 23 citations

Therapy of Peritoneal Carcinomatosis of Human Colon Cancer Xenografts With Yttrium 90—Labeled Anti—Carcinoembryonic Antigen Antibody ZCE025

1987 • 22 citations

Radioimmunoscintigraphy Using Monoclonal Antibodies to CEA, CA 19-9 and CA 125

1988 • 21 citations

Expression of monoclonal antibody-defined tumor markers in four carcinomas.

1989 • 20 citations

Imaging of colon carcinoma with 111‐indium‐labeled anti‐CEA monoclonal antibodies (INDACEA) prior to surgery

1987 • 19 citations

Role of Carcinoembryonic Antigen Assay in the Management of Cancer

1985 • 19 citations

Effect of yttrium-90-labeled anti-carcinoembryonic antigen monoclonal antibody on the morphology and phenotype of human tumors grown as peritoneal carcinomatosis in athymic mice

1989 • 18 citations

Antibody-guided irradiation of hepatic metastases using intrahepatically administered radiolabelled anti-CEA antibodies with simultaneous and reversible hepatic blood flow stasis using biodegradable starch microspheres

1987 • 18 citations

Radiation sensitivity and study of glutathione and related enzymes in human colorectal cancer cell lines

1988 • 16 citations

Preoperative prediction of outcome in patients with rectal and rectosigmoid cancer

1989 • 15 citations

Preoperative prediction of outcome in patients with rectal and rectosigmoid cancer

1990 • 12 citations

The expression of carcinoma-associated antigens and blood-group-related antigens in rectal carcinoids

1988 • 12 citations

Suppression of the growth of human colorectal carcinoma cells (LS174T) by radiolabeled monoclonal antibody (131I-MAbC27) in tissue culture and nude mice

1988 • 8 citations

The Spatial Distribution of Parenterally Administered Monoclonal Antibodies Against Cea in A Human Colorectal Tumour Xenograft

1989 • 8 citations

Biochemical Markers in Colorectal Cancer: Diagnostic and Therapeutic Implications

1988 • 8 citations

Biochemical markers in colorectal cancer: diagnostic and therapeutic implications.

1988 • 8 citations

Biodistribution of131I-labelled monoclonal antibodies in human colon tumours by anex vivo perfusion model

1988 • 6 citations