Bleomycin-induced DNA lesions at mutational hot spots: implications for the mechanism of double-strand cleavage.

DNA Repair Enzymes

1982 • 905 citations

Bleomycin-induced strand-scission of DNA. Mechanism of deoxyribose cleavage.

1981 • 415 citations

Molecular Aspects of Anti-Cancer Drug Action

1983 • 309 citations

Sequence specific cleavage of DNA by the antitumor antibiotics neocarzinostatin and bleomycin.

1978 • 299 citations

Interaction of bleomycin with DNA.

1978 • 250 citations

DNA repair: a laboratory manual of research procedures

1982 • 185 citations

Use of exonuclease III to determine the site of stable lesions in defined sequences of DNA: the cyclobutane pyrimidine dimer and cis and trans dichlorodiammine platinum II examples

1981 • 144 citations

Effect of apurinic/apyrimidinic endonucleases and polyamines on DNA treated with bleomycin and neocarzinostatin: specific formation and cleavage of closely opposed lesions in complementary strands

1988 • 130 citations

Chemistry of the alkali-labile lesion formed from iron(II) bleomycin and d(CGCTTTAAAGCG)

1988 • 83 citations

The DNA cleavage mechanism of iron-bleomycin. Kinetic resolution of strand scission from base propenal release.

1986 • 75 citations

Ferric bleomycin catalyzed reduction of 10-hydroperoxy-8,12-octadecadienoic acid: evidence for homolytic oxygen-oxygen bond scission

1988 • 35 citations

Enhanced bleomycin-mediated damage of DNA opposite charged nicks. A model for bleomycin-directed double strand scission of DNA.

1987 • 27 citations

Effect of in vitro cleavage of apurinic/apyrimidinic sites on bleomycin-induced mutagenesis of repackaged lambda phage

1990 • 27 citations

Bleomycin-induced mutagenesis in repackaged lambda phage: base substitution hotspots at the sequence C-G-C-C

1987 • 23 citations