Solution Structure and Backbone Dynamics of Long-[Arg3]insulin-like Growth Factor-I

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1996 • 5,190 citations

Insulin-Like Growth Factors and Their Binding Proteins: Biological Actions*

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Torsion angle dynamics for NMR structure calculation with the new program Dyana

1997 • 2,791 citations

Model-free approach to the interpretation of nuclear magnetic resonance relaxation in macromolecules

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1994 • 2,051 citations

Insulin-Like Growth Factors I and II. Peptide, Messenger Ribonucleic Acid and Gene Structures, Serum, and Tissue Concentrations*

1989 • 1,796 citations

The program XEASY for computer-supported NMR spectral analysis of biological macromolecules

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Actions of Insulin-Like Growth Factors

1985 • 1,141 citations

Insulin-Like Growth Factor-Binding Proteins in Serum and Other Biological Fluids: Regulation and Functions*

1997 • 1,056 citations

Insulin‐like growth factors I and II

1990 • 1,006 citations

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1993 • 975 citations

Backbone Dynamics of Ribonuclease HI: Correlations with Structure and Function in an Active Enzyme

1995 • 965 citations

The structure of 2Zn pig insulin crystals at 1.5 Å resolution

1988 • 662 citations

Intramolecular motions of a zinc finger DNA-binding domain from Xfin characterized by proton-detected natural abundance carbon-13 heteronuclear NMR spectroscopy

1991 • 566 citations

Insulin-like growth factor binding proteins and their role in controlling IGF actions

1997 • 510 citations

Three-dimensional structure of a genetically engineered variant of porcine growth hormone.

1987 • 457 citations

An alternative 3D NMR technique for correlating backbone 15N with side chain Hβ resonances in larger proteins

1991 • 273 citations

Novel recombinant fusion protein analogues of insulin-like growth factor (IGF)-I indicate the relative importance of IGF-binding protein and receptor binding for enhanced biological potency

1992 • 186 citations

Structure of the IGF-binding domain of the insulin-like growth factor-binding protein-5 (IGFBP-5): implications for IGF and IGF-I receptor interactions

1998 • 179 citations

Solution structure of human insulin-like growth factor 1: a nuclear magnetic resonance and restrained molecular dynamics study

1991 • 143 citations

Mutants of human insulin-like growth factor I with reduced affinity for the type 1 insulin-like growth factor receptor

1988 • 106 citations

Backbone dynamics of homologous fibronectin type III cell adhesion domains from fibronectin and tenascin

1997 • 84 citations

Three‐dimensional structure of human insulin‐like growth factor‐I (IGF‐I) determined by ¹H‐NMR and distance geometry

1993 • 74 citations

Production and characterization of recombinant insulin-like growth factor-I (IGF-I) and potent analogues of IGF-I, with Gly or Arg substituted for Glu 3, following their expression in Escherichia coli as fusion proteins

1992 • 70 citations

A key functional role for the insulin-like growth factor 1 N-terminal pentapeptide

1989 • 70 citations

Analysis of the Backbone Dynamics of Interleukin-8 by 15N Relaxation Measurements

1993 • 67 citations

Solution structure of human insulin-like growthfactor II. Relationship to receptor and binding protein interactions

1995 • 63 citations

Native and Non-native Structure in a Protein-folding Intermediate: Spectroscopic Studies of Partially Reduced IGF-I and an Engineered Alanine Model

1996 • 58 citations

Solution structure of human insulin-like growth factor II; recognition sites for receptors and binding proteins.

1994 • 51 citations

Mini-proinsulin and mini-IGF-I: homologous protein sequences encoding non-homologous structures

1998 • 49 citations

Specific binding of insulin-like growth factors 1 and 2 to the type 1 and type 2 receptors respectively

1988 • 46 citations

1H-NMR Assignment and Secondary Structure of Human Insulin-Like Growth Factor-I(IGF-I) in Solution

1992 • 34 citations

Mutations in the B-domain of insulin-like growth factor-I influence the oxidative folding to yield products with modified biological properties

1995 • 33 citations

Solution structure of a mini IGF‐1

1996 • 28 citations

Involvement of phenylalanine 23 in the binding of IGF-1 to the insulin and type I IGF receptor

1996 • 15 citations

Secondary structure determination of ¹⁵N‐labelled human Long‐[Arg‐3]‐insulin‐like growth factor 1 by multidimensional NMR spectroscopy

1997 • 8 citations