The Development and Application of a Novel Safety-Catch Linker for BOC-Based Assembly of Libraries of Cyclic Peptides^,1

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

Hypothalamic Polypeptide That Inhibits the Secretion of Immunoreactive Pituitary Growth Hormone

1973 • 3,509 citations

Applications of Combinatorial Technologies to Drug Discovery. 1. Background and Peptide Combinatorial Libraries

1994 • 1,130 citations

Applications of Combinatorial Technologies to Drug Discovery. 2. Combinatorial Organic Synthesis, Library Screening Strategies, and Future Directions

1994 • 1,126 citations

In situ neutralization in Boc‐chemistry solid phase peptide synthesis

1992 • 1,038 citations

Cyclosporin A Specifically Inhibits Function of Nuclear Proteins Involved in T Cell Activation

1989 • 679 citations

Molecular Cloning of the Thyrotropin Receptor

1989 • 529 citations

A potent cyclic hexapeptide analogue of somatostatin

1981 • 413 citations

Chemical Approaches to the Synthesis of Peptides and Proteins

2020 • 330 citations

Activation Method to Prepare a Highly Reactive Acylsulfonamide “Safety-Catch” Linker for Solid-Phase Synthesis¹

1996 • 248 citations

Polymer-bound oxime esters as supports for solid-phase peptide synthesis. The preparation of protected peptide fragments

1980 • 231 citations

Carbon-Carbon Bond-Forming Methods on Solid Support. Utilization of Kenner's "Safety-Catch" Linker

1994 • 207 citations

Template-Constrained Cyclic Peptides: Design of High-Affinity Ligands for GPIIb/IIIa

1994 • 161 citations

Toward Larger Chemical Libraries: Encoding with Fluorescent Colloids in Combinatorial Chemistry

2000 • 140 citations

The Chemistry of Chloroformates

1964 • 130 citations

Exocytosis in the Adrenal Medulla Demonstrated by Freeze-Etching

1973 • 129 citations

Oestradiol, sexual receptivity and cytosol progestin receptors in rat hypothalamus

1981 • 100 citations

Safety-catch anchoring linkage for synthesis of peptide amides by Boc/Fmoc strategy

1991 • 75 citations

Solid support linker strategies

1997 • 72 citations

A Backbone Linker for BOC-Based Peptide Synthesis and On-Resin Cyclization: Synthesis of Stylostatin 1^,

1999 • 68 citations

Rediscovering an Endothelin Antagonist (BQ-123): A Self-Deconvoluting Cyclic Pentapeptide Library

1996 • 54 citations

Safety-catch and multiply cleavable linkers in solid-phase synthesis

1998 • 50 citations

An ActivatedO→NAcyl Transfer Auxiliary: Efficient Amide-Backbone Substitution of Hindered “Difficult” Peptides

2000 • 46 citations

The mechanism of the hydrolysis of phenyl salicylate and catechol monobenzoate in the presence and absence of borate ions

1966 • 36 citations

Design and Synthesis of a Biologically Active Antibody Mimic Based on an Antibody-Antigen Crystal Structure

1994 • 33 citations

Titanium mediated reductive amination on solid support: Extending the utility of the 4-hydroxy-thiophenol linker

1998 • 32 citations

Cyclic hexapeptide analogs of somatostatin containing bridge modifications

1993 • 30 citations

A new reductive acidolysis final deprotection strategy in solid phase peptide synthesis. Use of a new safety-catch linker

1994 • 28 citations

Nucleotide chemistry. XVI. Synthesis of a diribonucleoside monophosphate by the .beta.-cyanoethyl phosphotriester method

1970 • 22 citations

Two‐step hard acid deprotection/cleavage procedure for solid phase peptide synthesis

1991 • 22 citations

Multistep deprotection for peptide chemistry

1993 • 22 citations

The development of solid phase protocols for a backbone amide linker and its application to the Boc-based assembly of linear peptides

1999 • 22 citations

Fmoc-based solid-phase peptide synthesis using dpr(phoc) linker. Synthesis of a C-terminal proline peptide

1996 • 20 citations

Improved Preparation of a Safety-Catch Linker for the Solid Phase Synthesis of Peptide Acids Finally Released into Aqueous Buffers

1998 • 20 citations

Macromolecular Sequencing and Synthesis: Selected Methods and Applications

1988 • 16 citations

A new safety-catch peptide-resin linkage for the direct release of peptides into aqueous buffers

1994 • 15 citations

Intramolecular hydrogen bonding catalysis of ester aminolysis in acetonitrile

1983 • 14 citations

Intramolecular general base catalysis in aprotic solvents

1976 • 7 citations