Combination treatment in bipolar disorder: a review of controlled trials

Efficacy of Divalproex vs Lithium and Placebo in the Treatment of Mania

1994 • 872 citations

Manic-Depressive Illness

1991 • 573 citations

Drug Therapy in the Prevention of Recurrences in Unipolar and Bipolar Affective Disorders

1984 • 569 citations

Clinical Factors in Lithium Carbonate Prophylaxis Failure

1974 • 518 citations

Two-Year Syndromal and Functional Recovery in 219 Cases of First-Episode Major Affective Disorder With Psychotic Features

2000 • 509 citations

12-Month Outcome of Patients With Bipolar Disorder Following Hospitalization for a Manic or Mixed Episode

1998 • 459 citations

Efficacy of Olanzapine in Combination With Valproate or Lithium in the Treatment of Mania in Patients Partially Nonresponsive to Valproate or Lithium Monotherapy

2002 • 450 citations

Combination of a Mood Stabilizer With Risperidone or Haloperidol for Treatment of Acute Mania: A Double-Blind, Placebo-Controlled Comparison of Efficacy and Safety

2002 • 419 citations

Rapid Cycling in Manic-Depressives Induced by Tricyclic Antidepressants

1979 • 405 citations

Double-Blind, Placebo-Controlled Comparison of Imipramine and Paroxetine in the Treatment of Bipolar Depression

2001 • 392 citations

The Increasing Use of Polypharmacotherapy for Refractory Mood Disorders

2000 • 319 citations

Gabapentin in bipolar disorder: a placebo‐controlled trial of adjunctive therapy1

2000 • 318 citations

Comparative Prophylactic Efficacy of Lithium, Carbamazepine, and the Combination in Bipolar Disorder

1997 • 313 citations

A double-blind comparison of valproate and lithium in the treatment of acute mania

1992 • 312 citations

A double-blind trial of bupropion versus desipramine for bipolar depression.

1994 • 281 citations

Lower suicide risk with long‐term lithium treatment in major affective illness: a meta‐analysis

2001 • 264 citations

Lithium Carbonate and Imipramine in the Prophylaxis of Unipolar and Bipolar II Illness

1982 • 213 citations

Double-Blind Comparison of Addition of a Second Mood Stabilizer Versus an Antidepressant to an Initial Mood Stabilizer for Treatment of Patients With Bipolar Depression

2000 • 209 citations

Mood Stabilizer Combinations: A Review of Safety and Efficacy

1998 • 202 citations

Valproate as an Adjunct to Neuroleptic Medication for the Treatment of Acute Episodes of Mania: A Prospective, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study

2000 • 175 citations

Excess Mortality in Schizophrenia and Affective Disorders

1978 • 175 citations

Sources of lithium resistance in mixed mania.

1986 • 168 citations

A Pilot Study of Lithium Carbonate Plus Divalproex Sodium for the Continuation and Maintenance Treatment of Patients With Bipolar I Disorder

1997 • 167 citations

Pharmacologic agents for the treatment of acute bipolar mania

2000 • 165 citations

The Effect of Comorbid Substance Use Disorders on the Course of Bipolar Disorder: A Review

1998 • 162 citations

The effect of long‐term lithium treatment on the mortality of patients with manic‐depressive and schizoaffective illness*

1992 • 156 citations

Carbamazepine and Haloperidol v Placebo and Haloperidol in Excited Psychoses

1984 • 153 citations

Prophylactic Lithium Carbonate With and Without Imipramine for Bipolar 1 Patients

1981 • 146 citations

Plasma Concentrations of Risperidone and 9-Hydroxyrisperidone: Effect of Comedication With Carbamazepine or Valproate

2000 • 133 citations

A comparison of haloperidol, lithium carbonate and their combination in the treatment of mania

1980 • 110 citations

Polypharmacy in psychiatric treatment. Patterns of psychotropic drug use in Austrian psychiatric clinics

1999 • 105 citations

Five-year mortality in lithium-treated manic-depressive patients

1991 • 94 citations

Changing Patterns of Psychotropic Medications Prescribed by Child Psychiatrists in the 1990s

1997 • 92 citations

Risperidone in the Elderly

1997 • 81 citations

Adding lithium carbonate to carbamazepine: antimanic efficacy in treatment‐resistant mania

1989 • 80 citations

Verapamil for the Treatment of Acute Mania: A Double-Blind, Placebo-Controlled Trial

1998 • 69 citations

Valproate prophylaxis in a prospective clinical trial of refractory bipolar disorder

1997 • 60 citations

Suicide and course of illness in major affective disorder

1988 • 60 citations

I Know This Much Is True

2000 • 56 citations

Factors predicting the use of multiple psychotropic medications.

1995 • 53 citations

Doubleblind evaluation of the antimanic properties of carbamazepine as a comedication to haloperidol

1989 • 46 citations

Proton magnetic resonance spectroscopy of lenticular nuclei in obsessive–compulsive disorder

1999 • 37 citations

Magnesium oxide augmentation of verapamil maintenance therapy in mania

2000 • 35 citations

Relapse Prevention in Manic Depressive Illness: Important and Unimportant Factors

1991 • 9 citations

[50 years lithium treatment].

2000 • 5 citations