A de novo mutation affecting human TrkB associated with severe obesity and developmental delay

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2003 • 858 citations

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2000 • 788 citations

Conditional Deletion Of Brain-Derived Neurotrophic Factor in the Postnatal Brain Leads to Obesity and Hyperactivity

2001 • 738 citations

Targeted disruption of the trkB neurotrophin receptor gene results in nervous system lesions and neonatal death

1993 • 670 citations

Mutations in the TRKA/NGF receptor gene in patients with congenital insensitivity to pain with anhidrosis

1996 • 622 citations

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2000 • 419 citations

Mice Lacking Brain-Derived Neurotrophic Factor Exhibit Visceral Sensory Neuron Losses Distinct from Mice Lacking NT4 and Display a Severe Developmental Deficit in Control of Breathing

1996 • 293 citations

Minireview: Human Obesity—Lessons from Monogenic Disorders

2003 • 224 citations

Crystal structures of the neurotrophin-binding domain of TrkA, TrkB and TrkC 1 1Edited by I. A. Wilson

1999 • 178 citations

Identification of in vivo brain-derived neurotrophic factor-stimulated autophosphorylation sites on the TrkB receptor tyrosine kinase by site-directed mutagenesis.

1994 • 51 citations

Activation loop tyrosines contribute varying roles to TrkB autophosphorylation and signal transduction

1998 • 28 citations