Effect of recombinant human erythropoietin on human IgE production in vitro

IgE production by normal human lymphocytes is induced by interleukin 4 and suppressed by interferons gamma and alpha and prostaglandin E2.

1988 • 939 citations

IL-4 is an essential factor for the IgE synthesis induced in vitro by human T cell clones and their supernatants.

1988 • 713 citations

Human recombinant interleukin 4 induces Fc epsilon receptors (CD23) on normal human B lymphocytes.

1987 • 449 citations

Phenotype of the accessory cell necessary for mitogen-stimulated T and B cell responses in human peripheral blood: delineation by its sensitivity to the lysosomotropic agent, L-leucine methyl ester.

1983 • 353 citations

Interleukin 5 enhances interleukin 4‐induced IgE production by normal human B cells. The role of soluble CD23 antigen

1988 • 265 citations

IL-4 inhibits the synthesis of IFN-gamma and induces the synthesis of IgE in human mixed lymphocyte cultures.

1990 • 262 citations

Endogenous interleukin 6 plays an obligatory role in interleukin 4‐dependent human IgE synthesis

1989 • 221 citations

Possible role of human lymphocyte receptor for IgE (CD23) or its soluble fragments in the in vitro synthesis of human IgE.

1988 • 175 citations

Interleukin-6 interacts with interleukin-4 and other hematopoietic growth factors to selectively enhance the growth of megakaryocytic, erythroid, myeloid, and multipotential progenitor cells

1989 • 156 citations

Expression of specific high-affinity binding sites for erythropoietin on rat and mouse megakaryocytes.

1989 • 129 citations

Receptors for erythropoietin in mouse and human erythroid cells and placenta

1989 • 111 citations

Binding the low affinity Fc epsilon R on B cells suppresses ongoing human IgE synthesis.

1989 • 110 citations

Receptors for erythropoietin in mouse and human erythroid cells and placenta

1989 • 88 citations

Characterization and use of monoclonal antibodies directed against human erythropoietin that recognize different antigenic determinants

1989 • 74 citations

A role for the macrophage in normal hemopoiesis: III. In vitro and in vivo erythropoietin gene expression in macrophages detected by in situ hybridization.

1989 • 69 citations

Characterization and use of monoclonal antibodies directed against human erythropoietin that recognize different antigenic determinants

1989 • 61 citations

Growth of clonogenic myeloblastic leukemic cells in the presence of human recombinant erythropoietin in addition to various human recombinant hematopoietic growth factors

1988 • 49 citations

Effect of recombinant human interleukin 4 on spontaneous in vitro human IgE synthesis^*

1988 • 41 citations

Subset of natural killer cells is induced by immune complexes to display Fc receptors for IgE and IgA and demonstrates isotype regulatory function.

1988 • 37 citations

Modulation of ongoing human immunoglobulin synthesis by natural killer cells

1987 • 33 citations

Recombinant human erythropoietin and hematopoietic progenitor cells in vivo [letter]

1989 • 30 citations

Human natural killer (NK) cells produce a late-acting B-cell differentiation activity

1988 • 28 citations

IgE-enhancing activity directly and selectively affects activated B cells: evidence for a human IgE differentiation factor.

1987 • 17 citations

Production of monoclonal antibodies against human erythropoietin and their use in the purification of human urinary erythropoietin

1988 • 10 citations