Therapeutic Safety Monitoring: What to Look for and When to Look for It

A Comparison of Valproate with Carbamazepine for the Treatment of Complex Partial Seizures and Secondarily Generalized Tonic–Clonic Seizures in Adults

1992 • 685 citations

Double-blind comparison of lamotrigine and carbamazepine in newly diagnosed epilepsy

1995 • 627 citations

Advances in epileptology

1990 • 543 citations

Epilepsy: A Comprehensive Textbook

1998 • 506 citations

Valproic acid hepatic fatalities

1987 • 491 citations

Chronic Antiepileptic Toxicity: A Review

1975 • 286 citations

Vigabatrin-associated retinal cone system dysfunction

1998 • 249 citations

Cytochrome P-450—Catalyzed Formation of Δ ⁴ -VPA, a Toxic Metabolite of Valproic Acid

1987 • 248 citations

Double‐Blind, Placebo‐Controlled Trial of Topiramate as Add‐on Therapy in Patients with Refractory Partial Seizures

1996 • 245 citations

Comparison of Status Epilepticus with Prolonged Seizure Episodes Lasting from 10 to 29 Minutes

1999 • 245 citations

Incidence of diphenylhydantoin gingival hyperplasia

1972 • 230 citations

Carbamazepine Side Effects in Children and Adults

1987 • 228 citations

Safety Review of Adult Clinical Trial Experience with Lamotrigine

1998 • 226 citations

Valproic acid hepatic fatalities.

1989 • 218 citations

Lamotrigine in Treatment of 120 Children with Epilepsy

1994 • 218 citations

THE HYPERKINETIC SYNDROME IN EPILEPTIC CHILDREN

1955 • 209 citations

Vigabatrin, a gabaergic antiepileptic drug, causes concentric visual field defects

1999 • 198 citations

In Whom Does Status Epilepticus Occur: Age‐Related Differences in Children

1997 • 192 citations

Safety of Topiramate: Adverse Events and Relationships to Dosing

1996 • 192 citations

Antiepileptic Drug Hypersensitivity Syndrome

1998 • 172 citations

Elevated Plasma Concentrations of Homocysteine in Antiepileptic Drug Treatment

1999 • 172 citations

Serum Hormones in Male Epileptic Patients Receiving Anticonvulsant Medication

1990 • 168 citations

Mechanisms of Idiosyncratic Hypersensitivity Reactions to Antiepileptic Drugs

1998 • 168 citations

Fatal Liver Failure in 16 Children with Valproate Therapy

1988 • 162 citations

Lamotrigine for the treatment of epilepsy in childhood

1995 • 153 citations

Safety of Long‐Term Lamotrigine in Epilepsy

1997 • 147 citations

Carbamazepine and hematological monitoring

1982 • 142 citations

A double-blind, placebo-controlled study of Vigabatrin three g/day in patients with uncontrolled complex partial seizures

1996 • 132 citations

Asymptomatic Hyperammonemia in Patients Receiving Valproic Acid

1982 • 129 citations

Gabapentin Toxicity in Children Manifesting as Behavioral Changes

1995 • 126 citations

Changes in Body Weight With Chronic, High-Dose Gabapentin Therapy

1997 • 124 citations

Tiagabine: The Safety Landscape

1995 • 122 citations

Phenytoin hypersensitivity

1979 • 120 citations

Valproate‐Associated Pancreatitis

1993 • 118 citations

Peripheral Neuropathy in Long-Term Diphenylhydantoin Therapy

1968 • 118 citations

MACROCYTOSIS AND MACROCYTIC ANAEMIA CAUSED BY ANTICONVULSANT DRUGS

1958 • 115 citations

Carbamazepine. Pharmacology and clinical uses.

1981 • 111 citations

OXCARBAZEPINE

1999 • 111 citations

Effect of carbamazepine, phenytoin and phenobarbitone on serum levels of thyroid hormones and thyrotropin in humans

1978 • 105 citations

Thrombocytopenia Secondary to High Valproate Levels in Children With Epilepsy

1994 • 105 citations

Tiagabine-induced absence status in idiopathic generalized epilepsy

1999 • 105 citations

Antiepileptics and Blood Dyscrasias: A Cohort Study

1998 • 102 citations

Extracellular GABA in the Ventrolateral Thalamus of Rats Exhibiting Spontaneous Absence Epilepsy: A Microdialysis Study

1995 • 95 citations

Tiagabine and non-convulsive status epilepticus

1996 • 86 citations

Plasma total homocysteine concentrations in epileptic patients taking anticonvulsants

1997 • 86 citations

Adding Lamotrigine to Valproate: Incidence of Rash and Other Adverse Effects

1999 • 85 citations

Safety of tiagabine: summary of 53 trials

1999 • 84 citations

Drug points: Fulminant hepatic failure induced by lamotrigine

1995 • 83 citations

Two Cases of Nonconvulsive Status Epilepticus in Association with Tiagabine Therapy

1999 • 82 citations

Valproate Therapy Induces von Willebrand Disease Type I

1992 • 82 citations

Nonconvulsive Status Epilepticus in Two Patients Receiving Tiagabine Treatment

1998 • 81 citations

Positive and Negative Psychotropic Effects of Lamotrigine in Patients with Epilepsy and Mental Retardation

1998 • 78 citations

An audit of topiramate use in a general neurology clinic

1998 • 75 citations

Hyponatremia during carbamazepine therapy

1985 • 75 citations

Lamotrigine Associated with Insomnia

1999 • 74 citations

Multiple Effects of 5,5′-Diphenylhydantoin on the Thyroid Hormone System*

1984 • 72 citations

Zonisamide

1999 • 70 citations

Phenytoin hepatotoxicity

1979 • 68 citations

Incidence and severity of phenytoin‐induced gingival overgrowth in epileptic patients in General Medical Practice

1992 • 59 citations

Cerebellar Atrophy After Acute Phenytoin Intoxication

1997 • 57 citations

Allergic skin rash with lamotrigine and concomitant valproate therapy: evidence for an increased risk

1996 • 55 citations

Cerebellar atrophy following acute 0intoxication with phenytoin

1989 • 52 citations

Changes in thyroid function tests induced by 2 month carbamazepine treatment in l-thyroxine-substituted hypothyroid children

1986 • 52 citations

Evidence of inherited urea cycle defect in a case of fatal valproate toxicity.

1986 • 51 citations

Hepatotoxic Reactions Associated with Carbamazepine Therapy

1988 • 49 citations

Valproate Treatment and Platelet Function: The Role of Arachidonate Metabolites

1999 • 49 citations

Influence of Valproate Monotherapy on Platelet Activation and Hematologic Values

1999 • 48 citations

Phenytoin‐Induced Depression of Salivary IgA and Gingival Hyperplasia

1976 • 46 citations

Bone status after long-term anticonvulsant therapy in epileptic patients: Evaluation using quantitative ultrasound of calcaneus and phalanges

1997 • 39 citations

Phenytoin‐Related cerebellar degeneration without seizures

1977 • 39 citations

Clinical and EEG findings in complex partial status epilepticus with tiagabine

1999 • 37 citations

Anticonvulsant Therapy and Its Possible Consequences on Peripheral Nervous System: A Neurographic Study

1984 • 32 citations

EXFOLIATIVE DERMATITIS AND HEPATITIS DUE TO PHENOBARBITAL

1950 • 31 citations

Phenytoin-like hypersensitivity associated with lamotrigine

1997 • 28 citations

TEGRETOL IN TRIGEMINAL NEURALGIA WITH SPECIAL REFERENCE TO HEMATOPOIETIC SIDE EFFECTS

1969 • 25 citations

Seasonal Incidence of Phenytoin Allergy Unrelated to Plasma Levels

1985 • 25 citations

Subpopulations of lymphocytes in connective tissue from phenytoin‐induced gingival overgrowth

1985 • 21 citations

The Effect of of Dilantin upon Fibroblast Proliferation

1972 • 20 citations

Perspective on carbamazepine‐induced water intoxication

1986 • 19 citations

Carbamazepine effects on mononuclear blood cells in epileptic patients

1986 • 17 citations

[Drug hypersensitivity syndrome during treatment with valproic acid].

1995 • 15 citations

Tiagabin und nonkonvulsiver Status epilepticus

1999 • 14 citations

Chronic Anticonvulsive Therapy, Peripheral Nerve Conduction Velocity, and EMG

1981 • 11 citations

Cerebellar atrophy following acute intoxication with phenytoin

1990 • 11 citations

Evaluation of Gabapentin in an Outpatient and Office-based Sample of Epilepsy Patients

1998 • 3 citations

Delayed Reaction to Primidone in Pregnancy

1957 • 2 citations

[Evaluation of the status of peripheral nerves in patients on long-term treatment with anticonvulsants based on a study of H-reflex and F wave].

1986 • 1 citations

Deleted Work

1955 • 0 citations

Cited By (0)

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