Transforming growth factor-β1 regulates chemokine and complement production by human proximal tubular epithelial cells

Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix.

1986 • 2,499 citations

Transforming growth factor type beta induces monocyte chemotaxis and growth factor production.

1987 • 1,287 citations

Elevated expression of transforming growth factor-beta and proteoglycan production in experimental glomerulonephritis. Possible role in expansion of the mesangial extracellular matrix.

1990 • 555 citations

Transforming growth factor beta: the good, the bad, and the ugly.

1994 • 491 citations

Inflammatory and immunomodulatory roles of TGF-β

1989 • 450 citations

Expression of transforming growth factor-β isoforms in human glomerular diseases

1996 • 424 citations

Transgenic mice with increased plasma levels of TGF-beta 1 develop progressive renal disease.

1996 • 423 citations

Transforming growth factor beta (TGF-?) in inflammation: A cause and a cure

1992 • 417 citations

Transforming growth factor-β regulates production of proteoglycans by mesangial cells

1990 • 365 citations

Tissue culture of human kidney epithelial cells of proximal tubule origin

1984 • 317 citations

RANTES chemokine expression in cell-mediated transplant rejection of the kidney

1994 • 267 citations

Role of transforming growth factor-β1 in experimental chronic cyclosporine nephropathy

1996 • 215 citations

Production and cytokine-mediated regulation of monocyte chemoattractant protein-1 by human proximal tubular epithelial cells

1995 • 200 citations

ELEVATED EXPRESSION OF TRANSFORMING GROWTH FACTOR BETA AND PROTEOGLYCAN PRODUCTION IN EXPERIMENTAL GLOMERULONEPHRITIS

1990 • 196 citations

Intragraft TGF-β1 mRNA: A correlate of interstitial fibrosis and chronic allograft nephropathy

1996 • 193 citations

Interleukin 2 mediates stimulation of complement C3 biosynthesis in human proximal tubular epithelial cells.

1991 • 184 citations

The autocrine production of transforming growth factor-beta 1 during lymphocyte activation. A study with a monoclonal antibody-based ELISA.

1990 • 169 citations

Transforming growth factor-beta 1 inhibits the production of IL-8 and the transmigration of neutrophils through activated endothelium.

1996 • 162 citations

Monocyte chemotactic peptide-1 expression in acute and chronic human nephritides

1996 • 157 citations

Transforming growth factor-beta and matrix protein expression in acute and chronic rejection of human renal allografts.

1995 • 148 citations

In vitro and in vivo interleukin-8 production in human renal cortical epithelia

1992 • 138 citations

Tumor necrosis factor α and transforming growth factor β upregulate astrocyte expression of monocyte chemoattractant protein-1

1995 • 129 citations

Renal extracellular matrix accumulation in acute puromycin aminonucleoside nephrosis in rats.

1992 • 127 citations

Regulation of mesangial cell growth by polypeptide mitogens. Inhibitory role of transforming growth factor beta.

1989 • 122 citations

Possible role for CD40-CD40L in the regulation of interstitial infiltration in the kidney

1997 • 119 citations

Detection of urinary interleukin-8 in glomerular diseases

1994 • 117 citations

PI 3-Kinase-Dependent and Independent Chemotaxis of Human Neutrophil Leukocytes

1995 • 99 citations

Differential expression of complement C3 and C4 in the human kidney.

1993 • 97 citations

Transforming growth factor beta 1 regulates production of acute-phase proteins.

1990 • 96 citations

Tubular-Derived Growth Factors and Cytokines in the Pathogenesis of Tubulointerstitial Fibrosis: Implications for Human Renal Disease Progression

1994 • 89 citations

Regulation and production of IL-8 by human proximal tubular epithelial cells in vitro

1996 • 89 citations

Interferon-γ regulation of human renal cortical epithelial cell-derived monocyte chemotactic peptide-1

1993 • 87 citations

IFN-γ mediates stimulation of complement C4 biosynthesis in human proximal tubular epithelial cells

1993 • 81 citations

Expression of monocyte chemoattractant protein 1 in human osteoblastic cells stimulated by proinflammatory mediators

1994 • 73 citations

Transforming growth factor-β1 induces extracellular matrix formation in glomerulonephritis

1990 • 65 citations

Transforming growth factor beta mediates the angiotensin-II-induced stimulation of collagen type IV synthesis in cultured murine proximal tubular cells

1996 • 65 citations

INTERFERON-γ INDUCES BIOSYNTHESIS OF COMPLEMENT COMPONENTS C2, C4 AND FACTOR H BY HUMAN PROXIMAL TUBULAR EPITHELIAL CELLS

1997 • 63 citations

Detection and cellular localization of human C4 gene expression in the renal tubular epithelial cells and other extrahepatic epithelial sources.

1991 • 61 citations

TGF-beta: a cytokine mediator of glomerulosclerosis and a target for therapeutic intervention.

1995 • 57 citations

Expression and tissue localization of donor‐specific complement C3 synthesized in human renal allografts

1995 • 56 citations

The role of interstitial cells in the progression of renal diseases.

1992 • 55 citations

Role of proteoglycans and cytoskeleton in the effects of TGF-β1 on renal proximal tubule cells

1993 • 55 citations

Interleukin-1α enhances the biosynthesis of complement C3 and factor B by human kidney proximal tubular epithelial cells in vitro

1996 • 51 citations

Transforming growth factor-beta 1 (TGF-β1) down-regulates IgA Fc-receptor (CD89) expression on human monocytes

1996 • 49 citations

Differential expression of complement components in human fetal and adult kidneys

1996 • 43 citations

LOCAL TRANSCRIPTION OF COMPLEMENT C3 IN HUMAN ALLOGRAFT REJECTION

1994 • 41 citations

Transforming growth factor-beta 1 inhibits inflammatory cytokine-induced C3 gene expression in astrocytes.

1994 • 40 citations

Biosynthesis of Complement C4 Messenger RNA in Normal Human Kidney

1989 • 38 citations

Adhesion molecules in renal diseases.

1995 • 32 citations

Differential effects of angiotensin II and transforming growth factor beta on the production of heparan sulfate proteoglycan by mesangial cells in vitro.

1996 • 30 citations

Intrarenal cytokine mRNA expression and location in normal and IgA nephropathy tissue: TGFα, TGFβ, IGF 1, IL-4 and IL-6

1994 • 30 citations

Induction of chemokine mRNA in bone marrow stromal cells: modulation by TGF-beta 1 and IL-4.

1995 • 27 citations

Transforming growth factor β modulates C3 and factor B biosynthesis and complement receptor 3 expression in cultured human monocytes

1995 • 25 citations

CsA, FK506, corticosteroids and rapamycin inhibit TNFα production by cultured PTEC

1993 • 25 citations

C3, C4, factor B and HLA-DR alpha mRNA expression in renal biopsy specimens from patients with IgA nephropathy.

1995 • 24 citations

Regulated expression of complement factor B in the human kidney

1996 • 23 citations

Adhesion Molecules in Renal Diseases

1996 • 20 citations

Regulation of acute phase reaction by transforming growth factor beta in cultured murine hepatocytes.

1991 • 9 citations

Transforming growth factor-beta and its receptors in rabbit renal proximal tubules after uninephrectomy.

1996 • 6 citations

CD32 expression and signaling is down‐regulated by transforming growth factor‐β1 on human monocytes

1996 • 4 citations

SYSTEMIC INJECTION OF MYELOPEROXIDASE IN MYELOPEROXIDASEIMMUNIZED BROWN-NORWAY RATS

1995 • 3 citations