Angiotensinogen Gene Polymorphism at −217 Affects Basal Promoter Activity and Is Associated with Hypertension in African-Americans

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Prevalence of Hypertension in the US Adult Population

1995 • 2,997 citations

Molecular basis of human hypertension: Role of angiotensinogen

1992 • 1,861 citations

Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells.

1991 • 1,684 citations

Scissors-Grip Model for DNA Recognition by a Family of Leucine Zipper Proteins

1989 • 996 citations

Biological Role of the CCAAT/Enhancer-binding Protein Family of Transcription Factors

1998 • 799 citations

CCAAT-Enhancer Binding Protein: A Component of a Differentiation Switch

1991 • 733 citations

Angiotensin II type 1 receptor gene polymorphisms in human essential hypertension.

1994 • 731 citations

The DNA Binding Domain of the Rat Liver Nuclear Protein C/EBP Is Bipartite

1989 • 661 citations

A family of C/EBP-related proteins capable of forming covalently linked leucine zipper dimers in vitro.

1991 • 604 citations

A nucleotide substitution in the promoter of human angiotensinogen is associated with essential hypertension and affects basal transcription in vitro.

1997 • 547 citations

Angiotensinogen gene is expressed and differentially regulated in multiple tissues of the rat.

1986 • 484 citations

Absence of linkage between the angiotensin converting enzyme locus and human essential hypertension

1992 • 386 citations

Elevated systolic blood pressure as a cardiovascular risk factor

2000 • 356 citations

Trends in the Prevalence of Hypertension, Antihypertensive Therapy, and Left Ventricular Hypertrophy from 1950 to 1989

1999 • 281 citations

Angiotensinogen as a risk factor for essential hypertension in Japan.

1994 • 258 citations

The serum angiotensinogen concentration and variants of the angiotensinogen gene in white and black children.

1995 • 245 citations

Expression of the liver-enriched transcriptional activator protein DBP follows a stringent circadian rhythm

1990 • 218 citations

Linkage of the angiotensinogen gene locus to human essential hypertension in African Caribbeans.

1995 • 193 citations

Angiotensinogen gene in human hypertension. Lack of an association of the 235T allele among African Americans.

1994 • 169 citations

Cellular Localization of Angiotensinogen Gene Expression in Brown Adipose Tissue and Mesentery: Quantification of Messenger Ribonucleic Acid Abundance Using Hybridization in Situ*

1987 • 147 citations

Transcriptional activation of adipogenesis

1999 • 135 citations

Structure and expression of the human angiotensinogen gene. Identification of a unique and highly active promoter.

1990 • 132 citations

Structure of Human Angiotensinogen Gene

1989 • 132 citations

The Ability of C/EBPβ but Not C/EBPα To Synergize with an Sp1 Protein Is Specified by the Leucine Zipper and Activation Domain

1997 • 130 citations

Molecular Genetics of Human Hypertension: Role of Angiotensinogen*

1997 • 130 citations

Role of C/A Polymorphism at −20 on the Expression of Human Angiotensinogen Gene

1999 • 126 citations

A Polymorphism of the Human Matrix γ-Carboxyglutamic Acid Protein Promoter Alters Binding of an Activating Protein-1 Complex and Is Associated with Altered Transcription and Serum Levels

2001 • 122 citations

Tissue-specific regulation of angiotensinogen mRNA accumulation by dexamethasone.

1987 • 100 citations

Longitudinal assessment of blood pressures in black and white children.

1993 • 95 citations

Similar frequencies of renin gene restriction fragment length polymorphisms in hypertensive and normotensive subjects.

1990 • 91 citations

Angiotensinogen levels and obesity in four black populations

1998 • 88 citations

Association of the Angiotensinogen Gene to Serum Angiotensinogen in Blacks and Whites

1997 • 84 citations

A -Acting DNA Element Located between TATA Box and Transcription Initiation Site Is Critical in Response to Regulatory Sequences in Human Angiotensinogen Gene

1996 • 83 citations

Role of the Renin–Angiotensin System in Blood Pressure Regulation and in Human Hypertension: New Insights from Molecular Genetics

1995 • 59 citations

Regulated Expression of Human Angiotensinogen Gene by Hepatocyte Nuclear Factor 4 and Chicken Ovalbumin Upstream Promoter-Transcription Factor

1999 • 40 citations

Interleukin-6 as a mediator responsible for inflammation-induced increase in plasma angiotensinogen.

1993 • 38 citations

Angiotensin receptor blockers: Evidence for preserving target organs

2001 • 36 citations

Exon-I is involved in positive as well as negative regulation of human angiotensinogen gene expression

1998 • 33 citations

Stimulation of angiotensinogen production in primary cultures of rat hepatocytes by glucocorticoid, cyclic adenosine 3',5'-monophosphate, and interleukin-6.

1992 • 31 citations

Transcriptional Regulation of Angiotensinogen Gene Expression

1997 • 27 citations

DBP Binds to the Proximal Promoter and Regulates Liver- Specific Expression of the Human Angiotensinogen Gene

1998 • 23 citations

Orphan receptor Arp-1 binds to the nucleotide sequence located between TATA box and transcriptional initiation site of the human angiotensinogen gene and reduces estrogen induced promoter activity

1999 • 21 citations

cAMP increases the expression of human angiotensinogen gene through a combination of cyclic AMP responsive element binding protein and a liver specific transcription factor.

2000 • 12 citations

Species-Specific Induction of Angiotensinogen mRNA in Transgenic Mouse Liver during Acute Phase Reaction.

1992 • 5 citations