Association and Interaction of the IL4R, IL4, and IL13 Loci with Type 1 Diabetes among Filipinos

Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus

2002 • 10,002 citations

Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus

1997 • 6,073 citations

Kinetic PCR Analysis: Real-time Monitoring of DNA Amplification Reactions

1993 • 2,177 citations

Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population.

1995 • 1,977 citations

Insulin-Dependent Diabetes Mellitus

1996 • 1,171 citations

The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Belgian Diabetes Registry

1996 • 794 citations

Lineage commitment in the immune system: the T helper lymphocyte grows up

2000 • 627 citations

Testing for linkage disequilibrium in genotypic data using the Expectation-Maximization algorithm

1996 • 578 citations

Assessing the role of HLA-linked and unlinked determinants of disease.

1987 • 548 citations

The role of HLA class II genes in insulin-dependent diabetes mellitus: molecular analysis of 180 Caucasian, multiplex families.

1996 • 468 citations

A cluster of seven tightly linked polymorphisms in the IL-13 gene is associated with total serum IgE levels in three populations of white children

2000 • 415 citations

Genetics of type 1 diabetes mellitus

2002 • 354 citations

Gene-Gene Interaction in Asthma: IL4RA and IL13 in a Dutch Population with Asthma

2002 • 344 citations

An IL-13 promoter polymorphism associated with increased risk of allergic asthma

1999 • 292 citations

Seven Regions of the Genome Show Evidence of Linkage to Type 1 Diabetes in a Consensus Analysis of 767 Multiplex Families

2001 • 264 citations

The polymorphisms S503P and Q576R in the interleukin‐4 receptor α gene are associated with atopy and influence the signal transduction

1999 • 248 citations

The interleukin-13 receptor α2 chain: an essential component for binding and internalization but not for interleukin-13–induced signal transduction through the STAT6 pathway

2001 • 216 citations

Association of asthma and the interleukin‐4 promoter gene in Japanese

1998 • 202 citations

Polymorphisms in the IL4 , IL4RA , and FCERIB genes and asthma severity

2000 • 193 citations

IDDM2-VNTR-encoded Susceptibility to Type 1 Diabetes: Dominant Protection and Parental Transmission of Alleles of the Insulin Gene-linked Minisatellite Locus

1996 • 165 citations

The HLA class I A locus affects susceptibility to type 1 diabetes

2002 • 126 citations

Decreased IL-4 production in new onset type I insulin-dependent diabetes mellitus.

1996 • 115 citations

The HLA class II locus DPB1 can influence susceptibility to type 1 diabetes.

2000 • 104 citations

Interleukin-13 prevents autoimmune diabetes in NOD mice.

1999 • 85 citations

The association of specific HLA class I and II alleles with type 1 diabetes among Filipinos

2002 • 74 citations

A novel polymorphism in the 5′ promoter region of the human interleukin-4 receptor α-chain gene is associated with decreased soluble interleukin-4 receptor protein levels

2001 • 72 citations

Association of IL4R Haplotypes With Type 1 Diabetes

2002 • 70 citations

Association of HLA-DPB1*0301 With IDDM in Mexican-Americans

1996 • 63 citations

Type I (Insulin-Dependent) Diabetes Is a Th1- and Th2-Mediated Autoimmune Disease

1999 • 58 citations

IDDM12 ( CTLA4 ) on 2q33 and IDDM13 on 2q34 in Genetic Susceptibility to Type 1 Diabetes (Insulin-dependent)

1999 • 58 citations

The Promoter Region of the CTLA4 Gene is Associated with Type 1 Diabetes Mellitus

2001 • 28 citations

In Vitro Interleukin‐13 Production by Peripheral Blood in Patients with Newly Diagnosed Insulin‐Dependent Diabetes Mellitus and Their First Degree Relatives

2000 • 21 citations

Antibodies to GAD65 and a tyrosine phosphatase-like molecule IA-2ic in Filipino type 1 diabetic patients.

1999 • 19 citations

Association of CTLA-4 variation with type I diabetes in Filipinos

2002 • 19 citations