A Cosmid and Yeast Artificial Chromosome Contig Containing the Complete Ryanodine Receptor (RYR1) Gene

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Complementary DNA Sequencing: Expressed Sequence Tags and Human Genome Project

1991 • 2,286 citations

Identification of a Mutation in Porcine Ryanodine Receptor Associated with Malignant Hyperthermia

1991 • 1,485 citations

Primary structure and expression from complementary DNA of skeletal muscle ryanodine receptor

1989 • 1,132 citations

An electrophoretic karyotype for yeast.

1985 • 787 citations

Identification of deletion mutations and three new genes at the familial polyposis locus

1991 • 769 citations

Molecular cloning of cDNA encoding human and rabbit forms of the Ca2+ release channel (ryanodine receptor) of skeletal muscle sarcoplasmic reticulum.

1990 • 644 citations

Molecular cloning of cDNA encoding the Ca2+ release channel (ryanodine receptor) of rabbit cardiac muscle sarcoplasmic reticulum.

1990 • 617 citations

Ryanodine receptor gene is a candidate for predisposition to malignant hyperthermia

1990 • 508 citations

Localization of the malignant hyperthermia susceptibility locus to human chromosome 19ql2–13.2

1990 • 377 citations

Yeast artificial chromosome libraries containing large inserts from mouse and human DNA.

1991 • 331 citations

Isolation of Single-Copy Human Genes from a Library of Yeast Artificial Chromosome Clones

1989 • 316 citations

A substitution of cysteine for arginine 614 in the ryanodine receptor is potentially causative of human malignant hyperthermia

1991 • 313 citations

Interphase and Metaphase Resolution of Different Distances Within the Human Dystrophin Gene

1990 • 260 citations

Estimating Genomic Distance from DNA Sequence Location in Cell Nuclei by a Random Walk Model

1992 • 239 citations

Abnormal sarcoplasmic reticulum ryanodine receptor in malignant hyperthermia.

1988 • 238 citations

Chromosomal Region of the Cystic Fibrosis Gene in Yeast Artificial Chromosomes: A Model for Human Genome Mapping

1990 • 238 citations

The proximity of DNA sequences in interphase cell nuclei is correlated to genomic distance and permits ordering of cosmids spanning 250 kilobase pairs

1989 • 230 citations

Mapping of human chromosome Xq28 by two-color fluorescence in situ hybridization of DNA sequences to interphase cell nuclei.

1991 • 226 citations

A Comprehensive Genetic Linkage Map of the Human Genome

1992 • 213 citations

Abnormal ryanodine receptor channels in malignant hyperthermia

1990 • 208 citations

Calcium‐induced Ca²⁺ release from sarcoplasmic reticulum of pigs susceptible to malignant hyperthermia

1983 • 158 citations

Evidence for the localization of a malignant hyperthermia susceptibility locus (MHS2) to human chromosome 17q

1992 • 137 citations

Polymorphisms and deduced amino acid substitutions in the coding sequence of the ryanodine receptor (RYR1) gene in individuals with malignant hyperthermia

1992 • 134 citations

Evidence for genetic heterogeneity in malignant hyperthermia susceptibility

1991 • 115 citations

A high-resolution, fluorescence-based, semiautomated method for DNA fingerprinting

1989 • 113 citations

Assignment of the porcine calcium release channel gene, a candidate for the malignant hyperthermia locus, to the 6p11 → q21 segment of chromosome 6

1990 • 89 citations

The genetics of malignant hyperthermia.

1993 • 89 citations

Fluorescence in Situ Hybridization Mapping of Human Chromosome 19: Cytogenetic Band Location of 540 Cosmids and 70 Genes or DNA Markers

1993 • 81 citations

Evidence for linkage of the central core disease locus to the proximal long arm of human chromosome 19

1991 • 78 citations

The human ryanodine receptor gene: its mapping to 19q13.1, placement in a chromosome 19 linkage group, and exclusion as the gene causing myotonic dystrophy.

1990 • 77 citations

Assignment of a human DNA-repair gene associated with sister-chromatid exchange to chromosome 19

1986 • 76 citations

Evidence for genetic heterogeneity of malignant hyperthermia susceptibility.

1992 • 75 citations

A yeast artificial chromosome contig containing the complete Duchenne muscular dystrophy gene

1992 • 74 citations

Assignment of the gene for central core disease to chromosome 19

1990 • 71 citations

Lorist6, a cosmid vector with BamHI, NotI, ScaI and Hind III cloning sites and altered neomycin phosphotransferase gene expression

1987 • 71 citations

Alu-primed polymerase chain reaction for regional assignment of 110 yeast artificial chromosome clones from the human X chromosome: identification of clones associated with a disease locus.

1991 • 63 citations

Optimizing restriction fragment fingerprinting methods for ordering large genomic libraries

1990 • 62 citations

Monochromosomal rodent-human hybrids from microcell fusion of human lymphoblastoid cells containing an inserted dominant selectable marker

1990 • 62 citations

Refined genetic localization for central core disease.

1993 • 51 citations

Malignant Hyperthermia: A Review

1982 • 49 citations

Construction of long-range restriction maps in human DNA using pulsed field gel electrophoresis

1987 • 45 citations

Distinct immunopeptide maps of the sarcoplasmic reticulum Ca2+ release channel in malignant hyperthermia.

1990 • 45 citations

Etiopathogenetic defect of malignant hyperthermia: Hypersensitive calcium-release channel of skeletal muscle sarcoplasmic reticulum

1987 • 41 citations

CpG islands and HTF islands in the HLA class I region: investigation of the methylation status of class I genes leads to precise physical mapping of the HLA-B and -C genes

1988 • 36 citations

Assembly and analysis of cosmid contigs in the CEA-gene family region of human chromosome 19

1992 • 36 citations

Characterization of somatic cell hybrids by bivariate flow karyotyping and fluorescencein situ hybridization

1991 • 33 citations

Report of the Second International Workshop on Human Chromosome 19 Mapping 1992

1992 • 31 citations

Report of the committee on the genetic constitution of chromosome 19

1990 • 28 citations

High-resolution physical mapping of four microsatellite repeat markers near the RYR1 locus on chromosome 19q13.1 and apparent exclusion of the MHS locus from this region in two malignant hyperthermia susceptible families

1992 • 28 citations

Physical mapping and cloning of the proximal segment of the myotonic dystrophy gene region

1992 • 20 citations

Coincidence cloning of Alu PCR products.

1991 • 17 citations

Dinucleotide repeat polymorphism at the D19S191 locus

1992 • 16 citations

Fluorescence in Situ hybridization mapping of human chromosome 19: Mapping and verification of cosmid contigs formed by random restriction enzyme fingerprinting

1992 • 11 citations

Isolation of the human sex determining region from a Y-enriched yeast artificial chromosome library

1991 • 7 citations

Trinucleotide repeat polymorphism at the D19S190 locus

1992 • 4 citations

The interaction of high-resolution electrophoresis and computational analysis in genome mapping

1990 • 3 citations