Early Cellular Events in Pulmonary Fibrosis

Dual control of cell growth by somatomedins and platelet-derived growth factor.

1979 • 926 citations

Interstitial Lung Diseases of Unknown Cause

1984 • 696 citations

The Macrophage as an Effector Cell

1980 • 628 citations

Complement-Induced Granulocyte Aggregation

1980 • 520 citations

Interstitial Lung Diseases of Unknown Cause

1984 • 472 citations

The Biology and Pathology of Oxygen Radicals

1978 • 437 citations

Bleomycin-induced interstitial pulmonary disease in the nude, athymic mouse.

1979 • 425 citations

In vivo damage of rat lungs by oxygen metabolites.

1981 • 360 citations

Lymphocyte-Mediated Activation of Fibroblast Proliferation and Collagen Production

1978 • 358 citations

The chemotactic attraction of human fibroblasts to a lymphocyte-derived factor.

1976 • 357 citations

Changes in type of collagen synthesized as clones of chick chondrocytes grow and eventually lose division capacity.

1976 • 355 citations

Production of fibronectin by the human alveolar macrophage: mechanism for the recruitment of fibroblasts to sites of tissue injury in interstitial lung diseases.

1981 • 344 citations

The Pulmonary-Alveolar Macrophage

1979 • 331 citations

Collagen-and collagen peptide-induced chemotaxis of human blood monocytes.

1976 • 312 citations

Evidence for Chronic Inflammation as a Component of the Interstitial Lung Disease Associated with Progressive Systemic Sclerosis

1985 • 310 citations

Bleomycin-induced pulmonary fibrosis in the rat: inhibition by indomethacin.

1979 • 306 citations

Human Alveolar Macrophage Growth Factor for Fibroblasts

1982 • 301 citations

Role of fibronectin as a growth factor for fibroblasts.

1983 • 298 citations

Activity of a Macrophage Factor in Collagen Formation by Silica

1967 • 293 citations

Mononuclear cell modulation of connective tissue function: suppression of fibroblast growth by stimulation of endogenous prostaglandin production.

1980 • 282 citations

Ultrastructure of pulmonary mast cells in patients with fibrotic lung disorders.

1979 • 266 citations

Collagen polymorphism in idiopathic chronic pulmonary fibrosis.

1976 • 264 citations

THE EOSINOPHILIC PNEUMONIAS

1969 • 260 citations

Silica-stimulated monocytes release fibroblast proliferation factors identical to interleukin 1. A potential role for interleukin 1 in the pathogenesis of silicosis.

1984 • 254 citations

Products of Activated Lymphocytes: Leukocyte Inhibitory Factor (LIF) Distinct from Migration Inhibitory Factor (MIF)

1974 • 254 citations

Leukotactic Factor Produced by Sensitized Lymphocytes

1969 • 239 citations

Mechanisms of neutrophil accumulation in the lungs of patients with idiopathic pulmonary fibrosis.

1981 • 235 citations

Alveolar macrophage-derived chemotactic factor: kinetics of in vitro production and partial characterization.

1980 • 233 citations

Mechanism for the inflammatory response in primate lungs. Demonstration and partial characterization of an alveolar macrophage-derived chemotactic factor with preferential activity for polymorphonuclear leukocytes.

1977 • 215 citations

Pulmonary Fibrosis—A possible mechanism

1979 • 213 citations

Lung Maturation in the Fetal Rat: Acceleration by Injection of Fibroblast-Pneumonocyte Factor

1979 • 213 citations

Collagenase in the Lower Respiratory Tract of Patients with Idiopathic Pulmonary Fibrosis

1979 • 205 citations

The Eosinophil in Health and Disease.

1981 • 204 citations

Experimental paraquat poisoning: A histo‐logical and electron‐optical study of the changes in the lung

1971 • 177 citations

Proliferation of type II alveolar cells: A review of common responses in toxic lung injury

1976 • 159 citations

Eosinophil-mediated injury to lung parenchymal cells and interstitial matrix. A possible role for eosinophils in chronic inflammatory disorders of the lower respiratory tract.

1984 • 158 citations

The Effects of the Nude(nu/nu)Mutation on Bleomycin-induced Pulmonary Fibrosis

1983 • 145 citations

Morphometric estimates of infiltrative cellular changes during the development of bleomycin-induced pulmonary fibrosis in hamsters.

1983 • 144 citations

Pathogenesis of the granulomatous lung diseases.

1984 • 142 citations

Intensive care in the newborn

1977 • 141 citations

Pathogenic mechanisms in pulmonary fibrosis: collagen-induced migration inhibition factor production and cytotoxicity mediated by lymphocytes.

1976 • 131 citations

Mast cell heterogeneity and hyperplasia in bleomycin-induced pulmonary fibrosis of rats.

1984 • 128 citations

Bleomycin Hypersensitivity Pneumonitis

1978 • 126 citations

Rat lung fibroblast collagen metabolism in bleomycin-induced pulmonary fibrosis.

1985 • 126 citations

Silicosis and fibrogenesis: Fact and artifact

1979 • 120 citations

Pulmonary macrophage accumulation and asbestos-induced lesions at sites of fiber deposition.

1984 • 117 citations

Human alveolar macrophage inhibition of lung fibroblast growth. A prostaglandin-dependent process.

1985 • 110 citations

Potentiation of Butylated Hydroxytoluene-induced Acute Lung Damage by Oxygen

1983 • 108 citations

PRODUCTION OF MACROPHAGE MIGRATION INHIBITION FACTOR BY CONTINUOUS CELL LINES

1972 • 108 citations

The development of bleomycin-induced pulmonary fibrosis in neutrophil-depleted and complement-depleted rats.

1981 • 107 citations

Human lung macrophages induce histamine release from basophils and mast cells.

1985 • 103 citations

Deposition pattern of inorganic particles at the alveolar level in the lungs of rats and mice.

1983 • 102 citations

The ultrastructure and time sequence of the early stages of paraquat lung in rats

1974 • 98 citations

The role of cell injury and the continuing inflammatory response in the generation of silicotic pulmonary fibrosis

1984 • 97 citations

Modulation of collagen production following bleomycin-induced pulmonary fibrosis in hamsters. Presence of a factor in lung that increases fibroblast prostaglandin E2 and cAMP and suppresses fibroblast proliferation and collagen production.

1982 • 91 citations

Deposition and translocation of inhaled silica in rats. Quantification of particle distribution, macrophage participation, and function.

1982 • 91 citations

Eosinophil Function

1981 • 90 citations

Aerodynamic Size Distribution of Cromolyn Sodium at Ambient and Airway Humidity^1–3

1980 • 89 citations

Specific changes in the collagen phenotype of BALB 3T3 cells as a result of transformation by sarcoma viruses or a chemical carcinogen

1977 • 88 citations

Demonstration of the Chemotactic Properties of Collagen

1970 • 84 citations

Collagenase in the lower respiratory tract of patients with adult respiratory distress syndrome.

1985 • 82 citations

Mast cells in the human alveolar wall: an electronmicroscopic study.

1981 • 81 citations

Bleomycin-induced synthesis of type I procollagen by human lung and skin fibroblasts in culture

1980 • 78 citations

Role of polymorphonuclear leukocytes in silica-induced pulmonary fibrosis.

1984 • 76 citations

Paraquat-induced pulmonary fibrosis. Role of the alveolitis in modulating the development of fibrosis.

1984 • 74 citations

The Regulation of Lung Fibroblast Proliferation by Alveolar Macrophages in Experimental Silicosis^1–3

1984 • 71 citations

Interactions between Mast Cells, Fibroblasts and Connective Tissue Components

1985 • 70 citations

Characterization of Collagen and Its Precursors Synthesized by Rabbit‐Articular‐Cartilage Cells in Various Culture Systems

1976 • 70 citations

Pulmonary fibrosis in experimental acute respiratory disease.

1981 • 69 citations

A comparison of lymphocyte populations in lung tissue and in bronchoalveolar lavage fluid of rats at various times during the development of bleomycin-induced pulmonary fibrosis.

1984 • 68 citations

Role of alveolar macrophages in asbestosis: modulation of neutrophil migration to the lung after acute asbestos exposure.

1982 • 67 citations

C1q production and secretion by fibroblasts

1976 • 65 citations

Polymorphonuclear leukocyte and monocyte chemoattractants produced by human fibroblasts.

1979 • 63 citations

Type I collagen content is increased in lungs of patients with adult respiratory distress syndrome.

1983 • 62 citations

Cellular and extracellular changes following mast-cell secretion in avascular rat mesentery

1984 • 62 citations

Nitrogen Dioxide Effects on Alveolar Macrophages

1972 • 56 citations

The Eosinophil and the Lung

1982 • 53 citations

Characterization of collagen synthesized by normal and chemically transformed rat liver epithelial cell lines

1980 • 52 citations

Synthesis of collagen by chondrocytes in suspension culture: Modulation by calcium, 3′:5′-cyclic AMP, and prostaglandins

1977 • 51 citations

Secretion of Chemotaxins by Guinea Pig Lung Macrophages I. The Spectrum of Inflammatory Cell Responses

1980 • 50 citations

Modification of oxygen toxicity after lung injury by bleomycin in hamsters.

1982 • 48 citations

Lymphocyte–Macrophage Interactions and Macrophage Activation in the Expression of Antimicrobial Immunity in Vivo

1976 • 45 citations

Intradermal mast-cell secretion causing cutaneous mitogenesis

1982 • 44 citations

Potentiation of Bleomycin-induced Lung Injury by Exposure to 70% Oxygen

2015 • 44 citations

On the 48÷80-induced secretion of tissue mast cells and its mitogenic effect on nearby cells in the intact rat

1981 • 44 citations

NO₂Gas and NO₂^-Effects on Alveolar Macrophage Phagocytosis and Metabolism

1973 • 44 citations

The Role of Macrophage-derived Chemoattractant Activities in the Early Inflammatory Events of Bleomycin-induced Pulmonary Injury^1–4

1983 • 43 citations

Evidence of increased histamine levels of lung lavage fluids from patients with cryptogenic fibrosing alveolitis.

1981 • 43 citations

Respiratory Defense Mechanisms. Part II.

1978 • 42 citations

Alveolar Macrophage Stimulation and Population Changes in Silica-Exposed Rats

1981 • 42 citations

Enhanced release of a chemoattractant for alveolar macrophages after asbestos inhalation.

1983 • 42 citations

In Vitro Alveolar Macrophage Viability

1969 • 40 citations

Elevated Ratios of Type I/III Collagen in the Lungs of Chronically Ventilated Neonates with Respiratory Distress

1984 • 38 citations

Collagen Crosslinking in Lungs of Rats with Experimental Silicosis

1986 • 38 citations

Pulmonary fibrosis: Bronchoalveolar cell types and impaired function of alveolar macrophages in experimental silicosis

1982 • 38 citations

The direct effects of dusts on lung fibroblasts grown

1971 • 37 citations

The effects of silica dust and alveolar macrophages on lung fibroblasts grown

1974 • 34 citations

Induction of early alveolar injury by inhaled asbestos and silica.

1985 • 34 citations

Serum from pneumonectomized rabbits stimulates alveolar type II cell proliferation in vitro.

1980 • 34 citations

THE CHEMOTAXIS OF SELECTED CELL TYPES TO CONNECTIVE TISSUE DEGRADATION PRODUCTS

1975 • 33 citations

Cellular sensitivity to collagen in bleomycin-treated rats.

1982 • 33 citations

Effect of the Beige Mutation on Bleomycin-induced Pulmonary Fibrosis in Mice^1,2

1983 • 32 citations

Morphometry of In Situ and Lavaged Pulmonary Alveolar Macrophages from Control and Ozone-Exposed Rats

1983 • 31 citations

D-Penicillamine Prevents Collagen Accumulation in Lungs of Rats Given Bleomycin

1986 • 29 citations

Neutrophil chemotactic activity generation by alveolar macrophages after bleomycin injury.

1984 • 25 citations

Paraquat-induced injury of type II alveolar cells. An in vitro model of oxidant injury.

1984 • 25 citations

The Effects of Ozone on the Respiratory Epithelium and Alveolar Macrophages of Mice. I. Interferon Production

1976 • 22 citations

Cellular Interactions in Pulmonary Oxygen Toxicity in Vitro: I. Hyperoxic Induction of Fibroblast Factors Which Alter Growth and Lipid Metabolism of Pulmonary Epithelial Cells

1983 • 22 citations

Changes in type of collagen synthesized by chick fibroblasts in vitro in the presence of 5-bromodeoxyuridine

1976 • 21 citations

Experimental polymyxin B-induced interstitial lung disease characterized by an accumulation of cytotoxic eosinophils in the alveolar structures.

1985 • 21 citations

Bleomycin-induced increase of collagen turnover in IMR-90 fibroblasts: an in vitro model of connective tissue restructuring during lung fibrosis.

1982 • 21 citations

Pulmonary macrophages alter the collagen phenotype of lung fibroblasts

1981 • 19 citations

Dose-Dependent Effects in the Subacute Response of the Rat Lung to Quartz. I. The Cellular Response and the Activity of Lactate Dehydrogenase in the Airways

1983 • 19 citations

A Pathogenetic Mechanism in Lung Fibrosis

1980 • 18 citations

A Pathogenetic Mechanism in Lung Fibrosis

1980 • 17 citations

Alterations in Alveolar Macrophages in Hamsters Developing Pulmonary Fibrosis

1984 • 15 citations

Characteristics of cultured lung fibroblasts from bleomycin-treated rats. Comparisons with in vitro exposed normal fibroblasts.

1984 • 13 citations

Changes in the collagen pathway in fibrosis*1

1985 • 11 citations

In vitro hydrolase and phagocytic activities of alveolar macrophages.

1974 • 7 citations

AN ATTEMPT TO DETECT A MACROPHAGE FIBROGENIC FACTOR <italic>IN VITRO</italic>

1983 • 3 citations

Some implications of augmented collagen levels with bleomycin exposure or hyperoxic exposure of lung fibroblasts: fibrosis as altered phenotypic expression.

1983 • 2 citations

Macrophages and reparation with special reference to silicosis.

1978 • 1 citations

Deleted Work

1955 • 0 citations