Second line endocrine treatment of postmenopausal advanced breast cancer. Preliminary endocrine results of a 5-ARM randomized phase II trial of medium vs low dose aminoglutethimide, with or without hydrocortisone vs hydrocortisone alone (EORTC 10861)

Aminoglutethimide (Elipten-Ciba) as an Inhibitor of Adrenal Steroidogenesis: Mechanism of Action and Therapeutic Trial

1967 • 259 citations

A Randomized Trial Comparing Surgical Adrenalectomy with Aminoglutethimide plus Hydrocortisone in Women with Advanced Breast Cancer

1981 • 204 citations

Stereoselective Inhibition of Aromatase by Enantiomers of Aminoglutethimide*

1979 • 149 citations

Successful Medical Adrenalectomy With Amino-glutethimide

1974 • 137 citations

Aromatase activity in primary and metastatic human breast cancer

1987 • 137 citations

Biological Significance of Aromatase Activity in Human Breast Tumors*

1983 • 134 citations

Regulation of Aromatase Activity of Stromal Cells Derived from Human Adipose Tissue*

1982 • 108 citations

Endocrine effects of low dose aminoglutethimide alone in advanced postmenopausal breast cancer

1983 • 80 citations

Plasma estrone-sulfate assessment of reduced estrogen production during treatment of metastatic breast carcinoma

1982 • 75 citations

EFFECTS OF AMINOGLUTETHIMIDE ON ADRENAL STEROID SECRETION

1983 • 72 citations

A comparative trial of transsphenoidal hypophysectomy and estrogen suppression with aminoglutethimide in advanced breast cancer

1979 • 63 citations

Aromatase activity in breast adipose tissue from women with benign and malignant breast diseases

1987 • 63 citations

Primary hypothyroidism in breast cancer patients with irradiated supraclavicular lymph nodes

1985 • 55 citations

Alterations in the Metabolism of Oestrogens During Treatment with Aminoglutethimide in Breast Cancer Patients

1987 • 54 citations

A comparative evaluation of adrenalectomy and cortisone in the treatment of advanced mammary carcinoma

1961 • 51 citations

A comparison of the endocrine effects of low dose aminoglutethimide with and without hydrocortisone in postmenopausal breast cancer patients

1985 • 49 citations

Low-dose aminoglutethimide without steroid replacement in the treatment of postmenopausal women with advanced breast cancer

1985 • 46 citations

Aminoglutethimide in advanced breast cancer: Clinical results of a French multicenter randomized trial comparing 500 mg and 1 g/day

1985 • 42 citations

The use of prednisolone in the treatment of disseminated breast carcinoma

1958 • 41 citations

Compensatory Increase in TSH Secretion without Effect on Prolactin Secretion in Patients Treated with Aminoglutethimide

1977 • 40 citations

Regulation of aromatase activity of cultured adipose stromal cells by catecholamines and adrenocorticotropin

1984 • 34 citations

Effective inhibition by low dose aminoglutethimide of peripheral aromatization in postmenopausal breast cancer patients

1985 • 31 citations

Hydrocortisone alone vs hydrocortisone plus aminogluthethimide: a comparison of the endocrine effects in postmenopausal breast cancer

1984 • 30 citations

Successful medical adrenalectomy with amino-glutethimide. Role of altered drug metabolism

1974 • 28 citations

Pros and cons of aminoglutethimide for advanced postmenopausal breast cancer

1984 • 18 citations

Low dose aminoglutethimide without hydrocortisone for the treatment of advanced postmenopausal breast cancer

1989 • 18 citations

Long-term treatment with corticosteroids of patients with metastatic breast cancer.

1962 • 15 citations

Phase II study of low dose aminoglutethimide 250 mg/day plus hydrocortisone in advanced postmenopausal breast cancer

1989 • 14 citations

Influence of acth on aminoglutethimide induced reduction of plasma steroids in postmenopausal breast cancer

1984 • 11 citations

Endocrine effects of aminoglutethimide plus hydrocortisone versus effects of high dose of hydrocortisone alone in postmenopausal metastatic breast cancer

1987 • 9 citations

Clinical pharmacology of aminoglutethimide in patients with metastatic breast cancer

1987 • 8 citations

Recovery of Hypothalamic-Pituitary-Adrenal Function after Long Term Suppression by Aminoglutethimide and Hy dr ocortisone*

1981 • 4 citations