Targeted expression of HTLV-I envelope proteins in muscle by DNA immunization of mice

Selective extraction of polyoma DNA from infected mouse cell cultures

1967 • 5,357 citations

Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma

1980 • 5,022 citations

ANTIBODIES TO HUMAN T-LYMPHOTROPIC VIRUS TYPE-I IN PATIENTS WITH TROPICAL SPASTIC PARAPARESIS

1985 • 2,840 citations

Genetic immunization is a simple method for eliciting an immune response

1992 • 1,505 citations

Long-term persistence of plasmid DNA and foreign gone expression in mouse muscle

1992 • 743 citations

Gene inoculation generates immune responses against human immunodeficiency virus type 1.

1993 • 655 citations

Direct Gene Transfer into Skeletal MuscleIn Vivo: Factors Affecting Efficiency of Transfer and Stability of Expression

1993 • 380 citations

Protection of chimpanzees from high-dose heterologous HIV-1 challenge by DNA vaccination

1997 • 364 citations

Enhanced T-Cell Immunogenicity and Protective Efficacy of a Human Immunodeficiency Virus Type 1 Vaccine Regimen Consisting of Consecutive Priming with DNA and Boosting with Recombinant Fowlpox Virus

1998 • 334 citations

Potent, protective anti-HIV immune responses generated by bimodal HIV envelope DNA plus protein vaccination

1997 • 314 citations

Differential dependence on target site tissue for gene gun and intramuscular DNA immunizations.

1997 • 287 citations

An HTLV-I Vaccine: Why, How, for Whom?

1993 • 273 citations

Potential DNA Vaccine Integration into Host Cell Genome

1995 • 268 citations

DNA-mediated immunization to the hepatitis B surface antigen in mice: aspects of the humoral response mimic hepatitis B viral infection in humans.

1995 • 266 citations

Human T‐cell leukemia virus type I: Induction of syncytia and inhibition by patients' sera

1983 • 205 citations

Vaccination with HIV-1 gp120 DNA induces immune responses that are boosted by a recombinant gp120 protein subunit

1997 • 149 citations

Pseudotypes of human T-cell leukemia virus types 1 and 2: neutralization by patients' sera.

1984 • 139 citations

Studies of the Neutralizing Activity and Avidity of Anti-Human Immunodeficiency Virus Type 1 Env Antibody Elicited by DNA Priming and Protein Boosting

1998 • 123 citations

Discussion

1997 • 121 citations

Candidate AIDS Vaccines

1995 • 104 citations

Desmin sequence elements regulating skeletal muscle-specific expression in transgenic mice

1993 • 101 citations

Epidemiology of HTLV-I and associated diseases

1996 • 92 citations

A novel human T-leukemia virus type 1 cell-to-cell transmission assay permits definition of SU glycoprotein amino acids important for infectivity

1997 • 83 citations

Gene expression profiles in HTLV-I-immortalized T cells: deregulated expression of genes involved in apoptosis regulation

1999 • 79 citations

Long-Term Secretion of Therapeutic Proteins from Genetically Modified Skeletal Muscles

1996 • 76 citations

Induction of CD4+, human T lymphotropic virus type-1-specific cytotoxic T lymphocytes from patients with HAM/TSP. Recognition of an immunogenic region of the gp46 envelope glycoprotein of human T lymphotropic virus type-1.

1991 • 67 citations

Screening of HIV-1 Env Glycoproteins for the Ability to Raise Neutralizing Antibody Using DNA Immunization and Recombinant Vaccinia Virus Boosting

1997 • 64 citations

Different factors interact with myoblast-specific and myotube-specific enhancer regions of the human desmin gene

1993 • 59 citations

Immune Responses but No Protection against SHIV by Gene-Gun Delivery of HIV-1 DNA Followed by Recombinant Subunit Protein Boosts

1998 • 57 citations

Continuous epitopes of the human immunodeficiency virus type 1 (HIV-1) transmembrane glycoprotein and reactivity of human sera to synthetic peptides representing various HIV-1 isolates

1991 • 53 citations

Infection of rats with human T‐cell leukemia virus type‐I: Susceptibility of inbred strains, antibody response and provirus location

1994 • 44 citations

Identification of Novel Neutralization-Inducing Regions of the Human T Cell Lymphotropic Virus Type I Envelope Glycoproteins with Human HTLV-I-Seropositive Sera

1994 • 40 citations

Risk Potential of the Chromosomal Insertion of Foreign DNA

1995 • 38 citations

Human T‐cell leukemia virus type I: Pseudotype neutralization of Japanese And American isolates with human and rabbit sera

1985 • 36 citations

Costimulatory effects of T cell proliferation during infection with human T lymphotropic virus types I and II are mediated through CD80 and CD86 ligands.

1996 • 35 citations

Early studies on DNA-based immunizations for measles virus

1997 • 32 citations

DNA vaccination followed by macromolecular multicomponent peptide vaccination against HIV-1 induces strong antigen-specific immunity

1997 • 26 citations

Expression and immunogenicity in rats of recombinant adenovirus 5 DNA plasmids and vaccinia virus containing the HTLV-I-env gene

1997 • 24 citations

Induction of Neutralizing Antibodies Against HTLV-I Envelope Proteins After Combined Genetic and Protein Immunizations in Mice

1997 • 13 citations

Phylogenetic and Serological Characterization of Two Ugandan HIV-1 Isolates

1993 • 10 citations

Candidate AIDS Vaccine

1987 • 3 citations

Welcome addition to multivariate analysis

1975 • 1 citations