Phase-I study of intravenous modified lipid A

Eradication of spontaneous metastases and activation of alveolar macrophages by intravenous injection of liposomes containing muramyl dipeptide.

1981 • 322 citations

Lipid A: Chemical Structure and Biological Activity

1973 • 288 citations

Augmenting Agents in Cancer Therapy

1981 • 236 citations

Chemical Treatment of Tumors. V. Isolation of the Hemorrhage-Producing Fraction from <italic>Serratia marcescens (Bacillus prodigiosus)</italic> Culture Filtrate<xref ref-type="fn" rid="fn1"><sup>1</sup></xref>

1943 • 164 citations

Chemical Treatment of Tumors. IX. Reactions of Mice with Primary Subcutaneous Tumors to Injection of a Hemorrhage-Producing Bacterial Polysaccharide<xref ref-type="fn" rid="fn1"><sup>1</sup></xref>

1944 • 133 citations

Lipid A mutants of Salmonella typhimurium. Purification and characterization of a lipid A precursor produced by a mutant in 3-deoxy-D-mannooctulosonate-8-phosphate synthetase.

1977 • 118 citations

Isolation of a nontoxic lipid A fraction containing tumor regression activity.

1981 • 87 citations

Phenomenon of Local Tissue Reactivity.

1938 • 86 citations

Demonstration of nonspecific suppressor cells in the peripheral lymphocytes of cancer patients.

1978 • 78 citations

Preparation and antitumor activity of nontoxic lipid A

1982 • 77 citations

Characterization of two membrane-associated glycolipids from an Escherichia coli mutant deficient in phosphatidylglycerol.

1981 • 74 citations

The effects of experimental conditions on the expression of in vitro-mediated tumor cytotoxicity mediated by murine macrophages

1979 • 64 citations

End results in reticulum cell sarcoma of bone treated by bacterial toxin therapy alone or combined with surgery and/or radiotherapy (47 cases) or with concurrent infection (5 cases)

1971 • 54 citations

Immunobiological activities of synthetic lipid A analogs and related compounds as compared with those of bacterial lipopolysaccharide, re-glycolipid, lipid A, and muramyl dipeptide

1983 • 38 citations

Effect of indomethacin on blastogenesis of lymphocytes from cancer patients: Differentiation of patient types

1979 • 36 citations

Direct activation of tumoricidal properties in rat alveolar macrophages by Nocardia rubra cell wall skeleton

1980 • 31 citations

Le phénomène de Shwartzman dans le sarcome du Cobaye

1931 • 27 citations

Fate and Effect of Endotoxin Derivatives in Tumor-Bearing Mice

1971 • 25 citations

Heterogeneity within the population of NK and K cells.

1980 • 22 citations

Intralesional immunotherapy of malignant melanoma with mycobacterium smegmatis cell wall skeleton combined with trehalose dimycolate (p3)

1979 • 20 citations

The Tumor Necrotizing Effect of Lipoid A Component of Escherichia coli Endotoxin.

1961 • 15 citations

Phase I study of intradermal immunotherapy with oil-attached Mycobacterium smegmatis cell wall skeleton and trehalose dimycolate

1980 • 15 citations

Detoxification of Bacterial Endotoxin with Retention of Ability to Stimulate Non-Specific Resistance to Infection

1961 • 12 citations

Reaction of Spontaneous Mouse Carcinomas to Blood-Carried Bacterial Toxins

1935 • 11 citations

Phase I?II study of intralesional immunotherapy with oil-attached Mycobacterium smegmatis cell wall skeleton and trehalose dimycolate

1979 • 10 citations