Near-infrared oximetry of the brain

Brain magnetic resonance imaging with contrast dependent on blood oxygenation.

1990 • 6,189 citations

Noninvasive, Infrared Monitoring of Cerebral and Myocardial Oxygen Sufficiency and Circulatory Parameters

1977 • 3,758 citations

Noninvasive transcranial Doppler ultrasound recording of flow velocity in basal cerebral arteries

1982 • 3,000 citations

A review of the optical properties of biological tissues

1990 • 2,468 citations

Estimation of optical pathlength through tissue from direct time of flight measurement

1988 • 2,074 citations

Focal physiological uncoupling of cerebral blood flow and oxidative metabolism during somatosensory stimulation in human subjects.

1986 • 2,017 citations

Cerebral Blood Flow and Oxygen Consumption in Man

1959 • 1,965 citations

Brain magnetic resonance imaging with contrast-dependent oxygenation

1990 • 1,370 citations

DISEASES OF THE NERVOUS SYSTEM

1918 • 1,308 citations

Quantitative Measurement of Regional Cerebral Blood Flow and Oxygen Metabolism in Man Using 15O and Positron Emission Tomography

1980 • 1,240 citations

Near infrared spectroscopy (NIRS): A new tool to study hemodynamic changes during activation of brain function in human adults

1993 • 1,094 citations

THE DETERMINATION OF CEREBRAL BLOOD FLOW IN MAN BY THE USE OF NITROUS OXIDE IN LOW CONCENTRATIONS

1945 • 1,049 citations

Characterization of the near infrared absorption spectra of cytochrome aa3 and haemoglobin for the non-invasive monitoring of cerebral oxygenation

1988 • 908 citations

Optical pathlength measurements on adult head, calf and forearm and the head of the newborn infant using phase resolved optical spectroscopy

1995 • 630 citations

A finite element approach for modeling photon transport in tissue

1993 • 624 citations

Exercise‐induced arterial hypoxaemia in healthy human subjects at sea level.

1984 • 553 citations

Effect of alterations in the arterial carbon dioxide tension on the blood flow through the cerebral cortex at normal and low arterial blood pressures.

1965 • 515 citations

Quantification in tissue near–infrared spectroscopy

1997 • 481 citations

Methods of Quantitating Cerebral Near Infrared Spectroscopy Data

1988 • 471 citations

Quantitation of cerebral blood volume in human infants by near-infrared spectroscopy

1990 • 449 citations

Simultaneous Recording of Cerebral Blood Oxygenation Changes during Human Brain Activation by Magnetic Resonance Imaging and Near-Infrared Spectroscopy

1996 • 445 citations

Measurement of Cranial Optical Path Length as a Function of Age Using Phase Resolved Near Infrared Spectroscopy

1996 • 435 citations

Experimentally Measured Optical Pathlengths for the Adult Head, Calf and Forearm and the Head of the Newborn Infant as a Function of Inter Optode Spacing

1992 • 430 citations

Determination of Regional Cerebral Blood Flow by Inhalation of 133-Xenon

1967 • 380 citations

COTSIDE MEASUREMENT OF CEREBRAL BLOOD FLOW IN ILL NEWBORN INFANTS BY NEAR INFRARED SPECTROSCOPY

1988 • 375 citations

Decrease in parietal cerebral hemoglobin oxygenation during performance of a verbal fluency task in patients with Alzheimer's disease monitored by means of near-infrared spectroscopy (NIRS) — correlation with simultaneous rCBF-PET measurements

1997 • 361 citations

Increased Activity in Left Ventricular Receptors during Hemorrhage or Occlusion of Caval Veins in the Cat. ‐ A Possible Cause of the Vaso‐vagal Reaction

1972 • 356 citations

Time-resolved spectroscopy of hemoglobin and myoglobin in resting and ischemic muscle

1988 • 331 citations

The Oximeter, an Instrument for Measuring Continuously the Oxygen Saturation of Arterial Blood in Man

1942 • 330 citations

Reflexes from the heart.

1991 • 326 citations

Use of the water absorption spectrum to quantify tissue chromophore concentration changes in near-infrared spectroscopy

1994 • 309 citations

POSTHÆMORRHAGIC FAINTING

1944 • 286 citations

Autoregulation of Cerebral Blood Flow

1997 • 268 citations

Regional cerebrovascular oxygen saturation measured by optical spectroscopy in humans.

1991 • 259 citations

Separate measures of ATP utilization and recovery in human skeletal muscle.

1993 • 259 citations

Optical Time-of-Flight and Absorbance Imaging of Biologic Media

1993 • 230 citations

Quantification of adult cerebral hemodynamics by near-infrared spectroscopy

1994 • 222 citations

Validation in Volunteers of a Near-Infrared Spectroscope for Monitoring Brain Oxygenation In Vivo

1996 • 216 citations

Postural effects on muscle nerve sympathetic activity in man

1977 • 212 citations

Mitochondrial encephalomyopathy with coenzyme Q ₁₀ deficiency

1997 • 196 citations

Hypotension induced by passive head-up tilt: endocrine and circulatory mechanisms

1986 • 196 citations

Cerebral desaturation during exercise reversed by O₂ supplementation

1999 • 189 citations

Near-infrared spectroscopy in adults: effects of extracranial ischaemia and intracranial hypoxia on estimation of cerebral oxygenation

1994 • 179 citations

Magnetic resonance and near infrared spectroscopy for investigation of perinatal hypoxic-ischaemic brain injury.

1989 • 176 citations

Estimating Cerebral Blood Flow in Newborn Infants: Comparison of Near Infrared Spectroscopy and 133Xe Clearance

1991 • 166 citations

Near-infrared spectroscopy use in patients with head injury

1995 • 162 citations

Cerebral Autoregulation

2017 • 160 citations

Near-infrared spectroscopic localization of intracranial hematomas

1993 • 160 citations

Measurement of cytochrome oxidase and mitochondrial energetics by near–infrared spectroscopy

1997 • 157 citations

Measurement of hemoglobin flow and blood flow by near-infrared spectroscopy

1993 • 152 citations

Can Cerebrovascular Reactivity Be Measured With Near-Infrared Spectroscopy?

1995 • 148 citations

<title>Experimental study of migration depth for the photons measured at sample surface</title>

1991 • 142 citations

Assessment of Local Brain Activation

1997 • 142 citations

Cerebral Oximetry in Dead Subjects

1996 • 140 citations

Blood volume distribution during head-up tilt induced central hypovolaemia in man

1991 • 136 citations

Early detection of delayed traumatic intracranial hematomas using near-infrared spectroscopy

1995 • 136 citations

Intramuscular Deoxygenation during Exercise in Patients Who Have Chronic Anterior Compartment Syndrome of the Leg*

1997 • 134 citations

An observational study of near-infrared spectroscopy during carotid endarterectomy

1995 • 134 citations

Comparison between Near Infrared Spectroscopy and 133Xenon Clearance for Estimation of Cerebral Blood Flow in Critically Ill Preterm Infants

1993 • 132 citations

Regional changes in cerebral haemodynamics as a result of a visual stimulus measured by near infrared spectroscopy

1995 • 125 citations

Accuracy of a Cerebral Oximeter in Healthy Volunteers under Conditions of Isocapnic Hypoxia

1998 • 124 citations

Multiparametric continuous monitoring of brain metabolism and substrate delivery in neurosurgical patients

1997 • 120 citations

Muscle metabolism from near infrared spectroscopy during rhythmic handgrip in humans

1998 • 115 citations

CHANGES IN HUMAN CEREBRAL BLOOD FLOW CONSEQUENT ON ALTERATIONS IN BLOOD GASES

1935 • 114 citations

Cerebral oxygen metabolism during hypothermic circulatory arrest in humans

1993 • 108 citations

The Influence of Carbon Dioxide and Body Position on Near-Infrared Spectroscopic Assessment of Cerebral Hemoglobin Oxygen Saturation

1996 • 101 citations

Cerebral oxygen availability by NIR spectroscopy during transient hypoxia in humans

1990 • 97 citations

Clinical Evaluation of Near-Infrared Spectroscopy for Testing Cerebrovascular Reactivity in Patients With Carotid Artery Disease

1997 • 96 citations

Extracerebral absorption of near infrared light influences the detection of increased cerebral oxygenation monitored by near infrared spectroscopy.

1995 • 94 citations

Redox behavior of cytochrome oxidase in the rat brain measured by near-infrared spectroscopy

1997 • 94 citations

Measurement of Cerebral Blood Flow in Adult Humans Using Near Infrared Spectroscopy — Methodology and Possible Errors

1992 • 92 citations

A comparison of near‐infrared spectroscopy and jugular bulb oximetry in comatose patients resuscitated from a cardiac arrest

1998 • 92 citations

Estimation of Cerebral Venous Saturation in Newborn Infants by Near Infrared Spectroscopy

1993 • 92 citations

Localized near–infrared spectroscopy and functional optical imaging of brain activity

1997 • 91 citations

Retrograde Catheterization of the Right Internal Jugular Vein for Serial Measurements of Cerebral Venous Oxygen Content

1989 • 91 citations

Light-reflective cerebral oximetry and jugular bulb venous oxygen saturation during carotid endarterectomy

1994 • 89 citations

A CCD Spectrophotometer to Quantitate the Concentration of Chromophores in Living Tissue Utilising the Absorption Peak of Water at 975 nm

1989 • 83 citations

Thresholds for Hypoxic Cerebral Vasodilation in Volunteers

1997 • 79 citations

Impaired interhemispheric integration in brain oxygenation and hemodynamics in schizophrenia

1994 • 77 citations

Management of Acute Lower Gastrointestinal Haemorrhage in a Surgical Unit Over a 4-Year Period

1987 • 75 citations

A comparison of two systems for assessing cerebral venous oxyhaemoglobin saturation during cardiopulmonary bypass in humans

1993 • 73 citations

The influence of P_aO₂, pH and S_aO₂ on maximal oxygen uptake

1998 • 72 citations

Transcranial cerebral oximetry in random normal subjects

1998 • 71 citations

Near‐infrared spectrophotometry determined brain oxygenation during fainting

1998 • 70 citations

Cerebral haemoglobin oxygenation during sustained visual stimulation – a near–infrared spectroscopy study

1997 • 70 citations

Validation of Transcranial Near-Infrared Spectroscopy for Evaluation of Cerebral Blood Flow Autoregulation

1996 • 69 citations

Increase in vagal activity during hypotensive lower-body negative pressure in humans

1988 • 69 citations

Internal and External Carotid Contributions to Near-Infrared Spectroscopy During Carotid Endarterectomy

1997 • 67 citations

Non-Invasive Blood Glucose Monitoring by Means of near Infrared Spectroscopy: Methods for Improving the Reliability of the Calibration Models

1997 • 67 citations

Relationship between fluctuations in the cerebral hemoglobin oxygenation state and neuronal activity under resting conditions in man

1998 • 65 citations

Cerebral Hemoglobin and Optical Pathlength Influence Near-Infrared Spectroscopy Measurement of Cerebral Oxygen Saturation

1997 • 63 citations

Blood Glucose Measurement by Infrared Spectroscopy

1989 • 63 citations

Cerebral and circulatory haemodynamics before vasovagal syncope induced by orthostatic stress

1997 • 62 citations

Near Infrared Spectroscopy (NIRS) in Patients with Severe Brain Injury and Elevated Intracranial Pressure

1997 • 62 citations

Brain and muscle oxygen saturation during head‐up‐tilt‐induced central hypovolemia in humans

1995 • 62 citations

Near-infrared monitoring of cerebral oxygenation state during carotid endarterectomy

1996 • 61 citations

Middle cerebral artery velocity during head‐up tilt induced hypovolemic shock in humans

1993 • 61 citations

The effect of scalp ischaemia on measurement of cerebral blood volume by near-infrared spectroscopy

1996 • 61 citations

Simultaneous Assessment of Cerebral Oxygenation and Hemodynamics During a Motor Task

1997 • 58 citations

Cerebral oxygen saturation, transcranial Doppler ultrasonography and stump pressure in carotid surgery

1994 • 57 citations

Effects of Carotid Artery Compression Test on Regional Cerebral Blood Volume, Hemoglobin Oxygen Saturation and Cytochrome-C-Oxidase Redox Level in Cerebrovascular Patients

1986 • 56 citations

The Effect of Optode Positioning on Optical Pathlength in Near Infrared Spectroscopy of Brain

1990 • 56 citations

Use of near infrared spectroscopy to estimate cerebral blood flow in conscious and anaesthetized adult subjects

1996 • 55 citations

Ictal near infrared spectroscopy in temporal lobe epilepsy: a pilot study.

1996 • 55 citations

NIRS in Adults - Effects of Increasing Optode Separation

1994 • 52 citations

Noninvasive Assessment of Cerebral Hemodynamics and Tissue Oxygenation during Activation of Brain Cell Function in Human Adults Using Near Infrared Spectroscopy

1994 • 51 citations

Central venous oxygen saturation during hypovolaemic shock in humans

1993 • 48 citations

Profound Sympathoinhibition Complicating Hypovolemia in Humans

1989 • 48 citations

The contribution of extracranial blood oxygenation on near‐infrared spectroscopy during carotid thrombendarterectomy

1997 • 47 citations

Dynamic changes of cerebral oxygenation measured by brain tissue oxygen pressure and near infrared spectroscopy

1997 • 47 citations

Near-infrared reflected spectroscopy and electroencephalography during carotid endarterectomy —in search of a new shunt criterion

1998 • 47 citations

Pulsed multifrequency photoplethysmograph

1984 • 46 citations

Metabolic changes during experimental cerebral ischemia in hyperglycemic rats, observed by 31P and 1H magnetic resonance spectroscopy.

1988 • 44 citations

Influence of Respiration and Changes in Expiratory Pressure on Cerebral Haemoglobin Concentration Measured by near Infrared Spectroscopy

1996 • 41 citations

Regulation of subcutaneous blood flow during head‐up tilt (45°) in normals

1982 • 39 citations

Tolerance to head-up tilt and suspension with elevated legs.

1998 • 38 citations

Regional circulatory responses to hypocapnia and hypercapnia in bar-headed geese

1986 • 38 citations

Regional Cerebral Oxygen Saturation During Electroconvulsive Therapy

1996 • 37 citations

Versuch die Absorptions‐Verhältnisse des Cordierites für rothes Licht zu bestimmen

1851 • 37 citations

The influence of contralateral carotid stenosis and occlusion on cerebral oxygen saturation during carotid artery surgery

1995 • 36 citations

NIRS in the Temporal Region - Strong Influence of External Carotid Artery

1994 • 36 citations

Cerebral tissue oxygen status and psychomotor performance during lower body negative pressure (LBNP).

1990 • 35 citations

Neuromonitoring in defibrillation threshold testing. A comparison between EEG, near-infrared spectroscopy and jugular bulb oximetry.

1997 • 35 citations

Muscle oxygen saturation during surgery in the lithotomy position

1997 • 34 citations

Dysfunctions of automatic (P300a) and controlled (P300b) processing in Parkinson’s disease

1998 • 34 citations

Measurement of tissue oxygen consumption in patients with mitochondrial myopathy by noninvasive tissue oximetry

1997 • 33 citations

Current and emerging technology in G-LOC detection: noninvasive monitoring of cerebral microcirculation using near infrared.

1988 • 33 citations

Ueber die chemischen und optischen Eigenschaften des Blutfarbstoffs

1864 • 33 citations

The assessment of cerebral oxygenation during carotid endarterectomy utilising near infrared spectroscopy

1994 • 32 citations

Cerebral noradrenaline spillover and its relation to muscle sympathetic nervous activity in healthy human subjects

1997 • 31 citations

Cardiovascular and endocrine responses to head-up tilt and vasopressin infusion in humans

1986 • 30 citations

Effects of Carotid Compression, as Assessed by near Infrared Spectroscopy, upon Cerebral Blood Volume and Haemoglobin Oxygen Saturation

1987 • 30 citations

Ictal near infrared spectroscopy in temporal lobe epilepsy: a pilot study

1996 • 30 citations

Humoral vasodilatation in the forearm during voluntary hyperventilation

1957 • 30 citations

Comparison of changes in cerebral blood flow and cerebral oxygen saturation measured by near infrared spectroscopy (NIRS) after acetazolamide

1997 • 29 citations

Effect of Acetazolamide on Regional Cerebral Oxygen Saturation and Regional Cerebral Blood Flow

1995 • 29 citations

Sympathetic influence on cardiovascular responses to sustained head‐up tilt in humans

1995 • 29 citations

Central venous oxygen saturation during hypovolaemic shock in humans

1993 • 28 citations

Non-invasive measurement of cerebral blood volume in volunteers

1997 • 27 citations

Cerebral perfusion during human liver transplantation

1995 • 27 citations

A near-infrared spectrophotometric method for studying brain O2 sufficiency in man during +Gz acceleration.

1988 • 26 citations

Ueber die chemischen und optischen Eigenschaften des Blutfarbstoffs

1864 • 26 citations

Cerebral Oxygen Saturation and Blood Flow During Liver Transplantation

1997 • 26 citations

<title>Accurate NIRS measurement of muscle oxygenation by correcting the influence of a subcutaneous fat layer</title>

1998 • 25 citations

Redox changes in cat brain cytochrome-c oxidase after blood-fluorocarbon exchange

1990 • 24 citations

Measurement of Cerebral Venous Saturation in Adults using Near Infrared Spectroscopy

1997 • 24 citations

Passive Effects Of Gravity

1993 • 23 citations

Auditory evoked responses and near infrared spectroscopy during cardiac arrest

1995 • 22 citations

Noninvasive assessment of cerebral oxidative metabolism in the human newborn.

1994 • 21 citations

Erythrocyte lysate releases Ca²⁺from IP3-sensitive stores and activates Ca²⁺-dependent K⁺channels in rat basilar smooth muscle cells

1998 • 20 citations

Near-infrared optical responses in feline brain and skeletal muscle tissues during respiratory acid-base imbalance

1990 • 19 citations

Resolving extra- and intracranial signal changes during adult near infrared spectroscopy

1998 • 18 citations

Naloxone-provoked vaso-vagal response to head-up tilt in men

1995 • 15 citations

Mechanism of 201Thallium-chloride uptake in tumor cells and its relationship to potassium channels

1998 • 15 citations

A Method to Estimate the Ratio of Absorption Coefficients of Two Wavelengths Using Phase-Modulated Near Infrared Light Spectroscopy

1993 • 14 citations

Peripheral venous oxygen saturation during head-up tilt induced hypovolaemic shock in humans

1993 • 14 citations

Mesenteric artery response to head‐up tilt‐induced centralhypovolaemia and hypotension

1997 • 13 citations

Monitoring of Cerebral Hemodynamics Using Near-Infrared Spectroscopy During Local Intra-arterial Thrombolysis: Case Report

1998 • 13 citations

Cerebral Hemodynamic Changes During Carotid Artery Balloon Occlusion Monitored by Near-infrared Spectroscopy

1996 • 13 citations

An Automated System for the Measurement of the Response of Cerebral Blood Volume and Cerebral Blood Flow to Changes in Arterial Carbon Dioxide Tension Using Near Infrared Spectroscopy

1994 • 13 citations

Estimation of Concentration Ratios and the Redox States of the Cytochromes from Noisy Reflection Spectra Using Multicomponent Analysis Methods

1986 • 13 citations

Arterial diameter during central volume depletion in humans

1995 • 12 citations

Accurate NIRS measurement of muscle oxygenation by correcting the influence of a subcutaneous fat layer

1998 • 10 citations

Cerebral oximetry—Techniques

1998 • 10 citations

Non-invasive approaches to tissue bioenergetics

1994 • 10 citations

Subcutaneous oxygen and carbon dioxide tensions during head-up tilt-induced central hypovolaemia in humans

1996 • 9 citations

Near infrared spectroscopy of nitrosyl haemoglobin - relevance to in vivo detection of nitric oxide

1996 • 5 citations

A Method to Estimate the Ratio of Absorption Coefficients of Two Wavelengths Using Phase Modulated Near Infrared Light Spectroscopy

1994 • 5 citations

[Noninvasive diagnosis of cerebral ischemia with nuclear magnetic resonance tomography and near infrared spectroscopy].

1994 • 5 citations

Cholinergic blockade and the mesenteric artery response to head‐up tilt‐induced central hypovolaemia

1998 • 5 citations

Mitochondrial redox state as a “Gold Standard” of tissue hypoxia

1994 • 5 citations

The Simultaneous Measurement of the Redox State of Cytochrome Oxidase in Heart and Brain of Rat in Vivo by NIR

1992 • 5 citations

Preserved CO₂ response in cerebral and muscular blood vessels during cimetidine treatment

1991 • 3 citations

<title>Cerebral blood volume in humans by NIRS and PET</title>

1998 • 1 citations