Nodal Regulates Trophoblast Differentiation and Placental Development

Implantation and the placenta: key pieces of the development puzzle

1994 • 1,362 citations

Promotion of Trophoblast Stem Cell Proliferation by FGF4

1998 • 1,340 citations

Use of a recombinant retrovirus to study post-implantation cell lineage in mouse embryos.

1986 • 1,118 citations

A molecular pathway determining left-right asymmetry in chick embryogenesis

1995 • 781 citations

A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse

1994 • 769 citations

Zebrafish organizer development and germ-layer formation require nodal-related signals

1998 • 657 citations

Essential role of Mash-2 in extraembryonic development

1994 • 612 citations

Nodal is a novel TGF-β-like gene expressed in the mouse node during gastrulation

1993 • 606 citations

Smad2 role in mesoderm formation, left–right patterning and craniofacial development

1998 • 600 citations

Identification and Functional Characterization of a Smad Binding Element (SBE) in the JunB Promoter That Acts as a Transforming Growth Factor-β, Activin, and Bone Morphogenetic Protein-inducible Enhancer

1998 • 562 citations

Relationship between asymmetric nodal expression and the direction of embryonic turning

1996 • 547 citations

Conserved left–right asymmetry of nodal expression and alterations in murine situs inversus

1996 • 459 citations

Induction of the zebrafish ventral brain and floorplate requires cyclops/nodal signalling

1998 • 458 citations

Nodal-related signals induce axial mesoderm and dorsalize mesoderm during gastrulation

1995 • 415 citations

The glial cells missing-1 protein is essential for branching morphogenesis in the chorioallantoic placenta

2000 • 408 citations

nodal expression in the primitive endoderm is required for specification of the anterior axis during mouse gastrulation

1997 • 384 citations

Hxt encodes a basic helix-loop-helix transcription factor that regulates trophoblast cell development

1995 • 321 citations

Genetic dissection ofnodalfunction in patterning the mouse embryo

2001 • 320 citations

Regulation of Bone Morphogenetic Protein Activity by Pro Domains and Proprotein Convertases

1999 • 301 citations

JunB is essential for mammalian placentation

1999 • 261 citations

Activin Is a Local Regulator of Human Cytotrophoblast Cell Differentiation¹

1997 • 225 citations

The type I activin receptor ActRIB is required for egg cylinder organization and gastrulation in the mouse

1998 • 221 citations

Trophoblast Cell Differentiation: Establishment, Characterization, and Modulation of a Rat Trophoblast Cell Line Expressing Members of the Placental Prolactin Family*

1991 • 204 citations

Isolation and characterization of a novel trophoblast-specific cDNA in the mouse.

1988 • 193 citations

The Type II Activin Receptors Are Essential for Egg Cylinder Growth, Gastrulation, and Rostral Head Development in Mice

1999 • 192 citations

Nucleotide sequence of a growth-related mRNA encoding a member of the prolactin-growth hormone family.

1984 • 179 citations

A novel retrovirally induced embryonic lethal mutation in the mouse: assessment of the developmental fate of embryonic stem cells homozygous for the 413.d proviral integration

1991 • 147 citations

Trophoblastic Giant Cells of the Mouse Placenta as the Site of Proliferin Synthesis*

1988 • 144 citations

Molecular Cloning and Expression of Mouse Placental Lactogen I Complementary Deoxyribonucleic Acid

1987 • 133 citations

A new member of the prolactin-growth hormone gene family expressed in mouse placenta.

1985 • 126 citations

Progressive expression of trophoblast‐specific genes during formation of mouse trophoblast giant cells in vitro

1993 • 125 citations

The Transition to Endoreduplication in Trophoblast Giant Cells Is Regulated by the mSNA Zinc Finger Transcription Factor

1998 • 115 citations

Nodal Signaling Uses Activin and Transforming Growth Factor-β Receptor-regulated Smads

2001 • 114 citations

Molecular cloning of mouse placental lactogen cDNA.

1986 • 111 citations

Localization of Placental Lactogen-l in Trophoblast Giant Cells of the Mouse Placenta1

1991 • 107 citations

Insertional mutation of a gene involved in growth regulation of the early mouse embryo

1992 • 104 citations

Changes in prolactin receptor expression during pregnancy in the mouse ovary.

1993 • 103 citations

Recapitulation of the pathway for trophoblast giant cell differentiation in vitro: stage-specific expression of members of the prolactin gene family.

1994 • 86 citations

Trophoblast-specific transcription from the mouse placental lactogen-I gene promoter.

1993 • 68 citations

Characterization of Proliferin-Related Protein

1988 • 67 citations

Nodal signalling and the roles of the transcription factors SnR and Pitx2 in vertebrate left–right asymmetry

1999 • 66 citations

An Acute Phase Response Factor/NF-κB Site Downstream of the junB Gene That Mediates Responsiveness to Interleukin-6 in a Murine Plasmacytoma

1995 • 53 citations

Production of mouse placental lactogen-I and placental lactogen-II by the same giant cell.

1992 • 45 citations

Trophoblast-specific transcription from the mouse placental lactogen-I gene promoter

1993 • 44 citations

GATA-2 Restricts Prolactin-Like Protein A Expression to Secondary Trophoblast Giant Cells in the Mouse1

2000 • 40 citations

Production of Mouse Placental Lactogen-I by Trophoblast Giant Cellsin Uteroandin Vitro*

1990 • 38 citations

Protooncogene junB as a target for activin actions.

1993 • 25 citations

Nodal andBone morphogenetic protein 5 interact in murine mesoderm formation and implantation

2000 • 24 citations

Identification of Trophoblast-Specific Regulatory Elements in the Mouse Placental Lactogen II Gene

1998 • 18 citations

Activin inhibits but inhibin activates mouse placental lactogen-II secretion

1995 • 11 citations