Altered pattern of TCR/CD3-mediated protein-tyrosyl phosphorylation in T cells from patients with systemic lupus erythematosus. Deficient expression of the T cell receptor zeta chain.

The 1982 revised criteria for the classification of systemic lupus erythematosus

1982 • 14,553 citations

Derivation of the sledai. A disease activity index for lupus patients

1992 • 4,410 citations

Signal transduction by lymphocyte antigen receptors

1994 • 2,145 citations

ZAP-70: A 70 kd protein-tyrosine kinase that associates with the TCR ζ chain

1992 • 1,037 citations

Evolutionary conservation in the untranslated regions of actin mRNAs: DNA sequence of a human beta-actin cDNA

1984 • 973 citations

The cytoplasmic domain of the T cell receptor ζ chain is sufficient to couple to receptor-associated signal transduction pathways

1991 • 782 citations

Alterations in Signal Transduction Molecules in T Lymphocytes from Tumor-Bearing Mice

1992 • 650 citations

Complex Complexes: Signaling at the TCR

1996 • 512 citations

Activation of T Cells by a Tyrosine Kinase Activation Domain in the Cytoplasmic Tail of CD3 ε

1992 • 430 citations

Decreased production of and response to interleukin-2 by cultured lymphocytes from patients with systemic lupus erythematosus.

1982 • 421 citations

Co-association of CD3ζ with a receptor (CD16) for IgG Fc on human natural killer cells

1989 • 412 citations

Loss of T-cell receptor zeta chain and p56lck in T-cells infiltrating human renal cell carcinoma.

1993 • 385 citations

Inhibition of mast cell Fc epsilon R1-mediated signaling and effector function by the Syk-selective inhibitor, piceatannol.

1994 • 346 citations

Decreased expression of the signal-transducing zeta chains in tumor-infiltrating T-cells and NK cells of patients with colorectal carcinoma.

1993 • 344 citations

Evidence for linkage of a candidate chromosome 1 region to human systemic lupus erythematosus.

1997 • 279 citations

Characterization and expression of the gene for the human Fc receptor gamma subunit. Definition of a new gene family.

1990 • 225 citations

B cells from patients with systemic lupus erythematosus display abnormal antigen receptor-mediated early signal transduction events.

1996 • 220 citations

CD3-negative natural killer cells express ε TCR as part of a novel molecular complex

1989 • 210 citations

ZAP-70 binding specificity to T cell receptor tyrosine-based activation motifs: the tandem SH2 domains of ZAP-70 bind distinct tyrosine-based activation motifs with varying affinity.

1995 • 196 citations

Molecular cloning and chromosomal localization of the human T-cell receptor zeta chain: distinction from the molecular CD3 complex.

1988 • 180 citations

TCR/CD3 complex-mediated signal transduction pathway in T cells and T cell lines from patients with systemic lupus erythematosus.

1995 • 168 citations

Developmental and functional impairment of T cells in mice lacking CD3 zeta chains.

1993 • 164 citations

Role of TCR ζ Chain in T Cell Development and Selection

1994 • 141 citations

Natural killer function in systemic lupus erythematosus

1980 • 122 citations

Defective CD3-Mediated Cell Death in Activated T Cells from Patients with Systemic Lupus Erythematosus: Role of Decreased Intracellular TNF-α

1996 • 106 citations

Qualitative and quantitative contributions of the T cell receptor zeta chain to mature T cell apoptosis.

1996 • 94 citations

Deficient type I protein kinase A isozyme activity in systemic lupus erythematosus T lymphocytes.

1994 • 90 citations

The Syk/ZAP-70 protein tyrosine kinase connection to antigen receptor signalling processes

1995 • 83 citations

Structural similarity between Fc receptors and T cell receptors. Expression of the gamma-subunit of Fc epsilon RI in human T cells, natural killer cells and thymocytes.

1991 • 76 citations

T cell receptor complexes containing Fc epsilon RI gamma homodimers in lieu of CD3 zeta and CD3 eta components: a novel isoform expressed on large granular lymphocytes.

1992 • 72 citations

Cellular Immune Responses in Systemic Lupus Erythematosus

2015 • 67 citations

The gamma chain of the high-affinity receptor for IgE is a major functional subunit of the T-cell antigen receptor complex in gamma delta T lymphocytes.

1993 • 61 citations

Monoclonal antibodies reactive with the T cell receptor zeta chain: production and characterization using a new method.

1989 • 60 citations

A shift from negative to positive selection of autoreactive T cells by the reduced level of TCR signal in TCR-transgenic CD3 zeta-deficient mice.

1997 • 57 citations

OVERVIEW OF CELLULAR IMMUNE FUNCTION IN SYSTEMIC LUPUS ERYTHEMATOSUS

2004 • 52 citations

TCR ζ chain in T cell development and selection

1997 • 51 citations

Natural killer cells and interferon responses in patients with systemic lupus erythematosus.

1982 • 44 citations

Fc epsilonRI gamma can support T cell development and function in mice lacking endogenous TCR zeta-chain.

1997 • 43 citations

The cytoplasmic tail of the T cell receptor ζ chain is dispensable for antigen‐mediated T cell activation

1993 • 29 citations

CD3ζ and η chains are produced by alternative splicing from a common gene

1990 • 26 citations

Tyrosine Phosphorylation in Peripheral Lymphocytes from Patients with Systemic Lupus Erythematosus

1996 • 14 citations

Activation‐induced proteolysis of the cytoplasmic domain of ζ in T cell receptors and Fc receptors

1994 • 11 citations