Glutamine, cancer, and its therapy

A Progress Report on the Treatment of 157 Patients with Advanced Cancer Using Lymphokine-Activated Killer Cells and Interleukin-2 or High-Dose Interleukin-2 Alone

1987 • 2,769 citations

Natural Killer Cells: Their Roles in Defenses Against Disease

1981 • 1,353 citations

Clinical and Metabolic Efficacy of Glutamine-supplemented Parenteral Nutrition after Bone Marrow Transplantation

1992 • 763 citations

Intracellular free amino acid concentration in human muscle tissue.

1974 • 733 citations

Respiratory fuels and nitrogen metabolism in vivo in small intestine of fed rats. Quantitative importance of glutamine, glutamate, and aspartate.

1980 • 545 citations

Glutamine Utilization by the Small Intestine

1982 • 495 citations

GLUTAMINE METABOLISM IN LYMPHOCYTES: ITS BIOCHEMICAL, PHYSIOLOGICAL AND CLINICAL IMPORTANCE

1985 • 455 citations

Effect of a Glutamine‐Supplemented Enteral Diet on Methotrexate‐Induced Enterocolitis

1988 • 321 citations

Influence of the Postoperative State on the Intracellular Free Amino Acids in Human Muscle Tissue

1975 • 298 citations

Reciprocal regulation of glucose and glutamine utilization by cultured human diploid fibroblasts

1978 • 274 citations

Glutamine Preserves Liver Glutathione After Lethal Hepatic Injury

1992 • 258 citations

Total Parenteral Nutrition With Glutamine in Bone Marrow Transplantation and Other Clinical Applications (A Randomized, Double‐Blind Study)

1993 • 244 citations

Safety and Metabolic Effects of L‐Glutamine Administration in Humans

1990 • 243 citations

The role of glutamine in the oxidative metabolism of malignant cells.

1972 • 224 citations

Maximum activities of some enzymes of glycolysis, the tricarboxylic acid cycle and ketone-body and glutamine utilization pathways in lymphocytes of the rat

1982 • 217 citations

Relationship between glutamine concentration and protein synthesis in rat skeletal muscle

1988 • 206 citations

Glutathione Regulates Interleukin-2 Activity on Cytotoxic T-cells

1989 • 127 citations

Effects of Glutamine‐Supplemented Diets on Immunology of the Gut

1990 • 126 citations

Muscle and Plasma Amino Acids after Injury

1980 • 121 citations

Oral glutamine to prevent chemotherapy induced stomatitis: A pilot study

1996 • 118 citations

Elevated prostaglandin E2 production by monocytes is responsible for the depressed levels of natural killer and lymphokine-activated killer cell function in patients with breast cancer

1993 • 116 citations

The proportionality of glutaminase content to growth rate and morphology of rat neoplasms.

1969 • 112 citations

Ammonia production and glutamine incorporation into glutathione in the functioning rat kidney

1979 • 110 citations

Glutamine Enhances Selectivity of Chemotherapy Through Changes in Glutathione Metabolism

1995 • 108 citations

Glutamine-enriched diets support muscle glutamine metabolism without stimulating tumor growth

1990 • 104 citations

Glutamine Enhances Immunoregulation of Tumor Growth

1994 • 82 citations

Interorgan glutamine metabolism in the tumor-bearing rat

1988 • 70 citations

Glutamine Suppresses PGE2 Synthesis and Breast Cancer Growth

1996 • 53 citations

Regulation of endothelial cell prostaglandin synthesis by glutathione.

1991 • 49 citations

Glutamine requirements in the generation of lymphokine-activated killer cells

1994 • 46 citations

Prevention of chronic radiation enteropathy by dietary glutamine

1994 • 43 citations

Effect of Supplemental Dietary Glutamine on Methotrexate Concentrations in Tumors

1992 • 35 citations

Response of tumor and host to hyperalimentation and antiglutamine treatments

1990 • 21 citations

Inhibition of induction of natural killer activity in mice by general anesthesia (Avertin): Role of interferon

1991 • 11 citations