Cloning of the cDNA encoding human xanthine dehydrogenase (oxidase): Structural analysis of the protein and chromosomal location of the gene

The Metabolic Basis of Inherited Disease.

1988 • 7,933 citations

Oxygen-Derived Free Radicals in Postischemic Tissue Injury

1985 • 5,488 citations

The Metabolic Basis of Inherited Disease

1990 • 4,327 citations

Prosite: a dictionary of sites and patterns in proteins

1992 • 952 citations

Flavins and Flavoproteins

1984 • 692 citations

Interaction of pyrophosphate moieties with .alpha.-helixes in dinucleotide-binding proteins

1985 • 475 citations

Oxygen Radicals in Influenza-Induced Pathogenesis and Treatment with Pyran Polymer-Conjugated SOD

1989 • 420 citations

Flavins and Flavoproteins 1990

1991 • 370 citations

Dependence on O2- generation by xanthine oxidase of pathogenesis of influenza virus infection in mice.

1990 • 336 citations

Proteolytic conversion of xanthine dehydrogenase from the NAD-dependent type to the O2-dependent type. Amino acid sequence of rat liver xanthine dehydrogenase and identification of the cleavage sites of the enzyme protein during irreversible conversion by trypsin.

1990 • 276 citations

The Metabolic Basis of Inherited Disease

1967 • 263 citations

The mechanism of conversion of rat liver xanthine dehydrogenase from an NAD+-dependent form (type D) to an O2-dependent form (type O)

1976 • 214 citations

Purification and properties of the NAD+-dependent (type D) and O2-dependent (type O) forms of rat liver xanthine dehydrogenase

1976 • 209 citations

Isozymes: Structure, function and use in biology and medicine

1991 • 187 citations

Enzymes depending on the pterin molybdenum cofactor: sequence families, spectroscopic properties of molybdenum and possible cofactor-binding domains

1991 • 161 citations

Molecular cloning of a cDNA coding for mouse liver xanthine dehydrogenase. Regulation of its transcript by interferons in vivo

1992 • 121 citations

Sequence of the Structural Gene for Xanthine Dehydrogenase (rosy Locus) in Drosophila melanogaster

1987 • 115 citations

Plasma xanthine oxidase activity in patients with adult respiratory distress syndrome

1987 • 97 citations

Differences in redox and kinetic properties between NAD-dependent and O2-dependent types of rat liver xanthine dehydrogenase

1989 • 94 citations

Mutations Affecting Expression of the rosy Locus in Drosophila melanogaster

1987 • 89 citations

Enhanced xanthine oxidase activity in mice treated with interferon and interferon inducers

1984 • 82 citations

Superoxide radical involvement in the pathogenesis of burn shock.

1984 • 79 citations

The Nicotinamide Adenine Dinucleotide-Binding Site of Chicken Liver Xanthine Dehydrogenase

1989 • 67 citations

Properties of the xanthine oxidase from human liver

1969 • 60 citations

12-O-tetradecanoylphorbol-13-acetate-dependent induction of xanthine dehydrogenase and conversion to xanthine oxidase in murine epidermis.

1987 • 60 citations

Mapping point mutations in the Drosophila rosy locus using denaturing gradient gel blots.

1991 • 57 citations

The presence of desulfo xanthine dehydrogenase in purified and crude enzyme preparations from rat liver

1986 • 56 citations

Differences in Protein Structure of Xanthine Dehydrogenase and Xanthine Oxidase Revealed by Reconstitution with Flavin Active Site Probes

1989 • 51 citations

Use of rosy mutant strains of Drosophila melanogaster to probe the structure and function of xanthine dehydrogenase

1992 • 41 citations

Differences in Environment of FAD between NAD-dependent and O2-dependent Types of Rat Liver Xanthine Dehydrogenase Shown by Active Site Probe Study

1989 • 41 citations

Induction of xanthine oxidase and depression of cytochrome P-450 by interferon inducers: Genetic difference in the responses of mice

1985 • 33 citations

Isolation of giant DNA fragments from flow‐sorted human chromosomes

1990 • 24 citations

Xanthine dehydrogenase from Drosophila melanogaster: purification and properties of the wild-type enzyme and of a variant lacking iron-sulfur centers

1992 • 23 citations

Evidence for the existence of a tyrosyl residue in the nicotinamide adenine dinucleotide binding site of chicken liver xanthine dehydrogenase

1987 • 22 citations

Inhibition of milk xanthine oxidase by fluorodinitrobenzene.

1982 • 20 citations

Localization of the human gene for 230-kDal bullous pemphigoid autoantigen (BPAG1) to chromosome 6pter→q15

1991 • 13 citations

Molecular cloning and chromosomal mapping of a cDNA encoding human 80K-L protein: Major substrate for protein kinase C

1992 • 13 citations

The rosy locus and xanthine dehydrogenase in Drosophila melanogaster.

1990 • 7 citations

Active site chemical modification and sequencing of flavoproteins

1984 • 7 citations

Molecular genetic approaches to the study of E. coli flavoproteins

1984 • 7 citations