Binding sites of HeLa cell nuclear proteins on the upstream region of adenovirus type 5 E1A gene

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

DNAase footprinting a simple method for the detection of protein-DNA binding specificity

1978 • 2,092 citations

A gel electrophoresis method for quantifying the binding of proteins to specific DNA regions: application to components of the Escherichia coli lactose operon regulatory system

1981 • 1,991 citations

Identification of a protein-binding site that mediates transcriptional response of the c-fos gene to serum factors

1986 • 883 citations

Mechanism of activation of early viral transcription by the adenovirus E1A gene product

1981 • 604 citations

The interplay of DNA-binding proteins on the promoter of the mouse albumin gene

1987 • 532 citations

The adenovirus type 5 E1A transcriptional control region contains a duplicated enhancer element

1983 • 467 citations

ADENOVIRUS PROMOTERS AND E1A TRANSACTIVATION

1986 • 460 citations

Specific binding of a cellular DNA replication protein to the origin of replication of adenovirus DNA.

1983 • 318 citations

Role of an adenovirus E2 promoter binding factor in E1A-mediated coordinate gene control.

1987 • 290 citations

Interaction of a common cellular transcription factor, ATF, with regulatory elements in both E1a- and cyclic AMP-inducible promoters.

1988 • 290 citations

A 100-kD HeLa cell octamer binding protein (OBP100) interacts differently with two separate octamer-related sequences within the SV40 enhancer.

1987 • 263 citations

Nuclear factor III, a novel sequence-specific DNA-binding protein from HeLa cells stimulating adenovirus DNA replication

1986 • 256 citations

Sequence-specific interactions between cellular DNA-binding proteins and the adenovirus origin of DNA replication.

1987 • 169 citations

Contactpoint analysis of the HeLa nuclear factor I recognition site reveals symmetrical binding at one side of the DNA helix.

1987 • 168 citations

Structure and function of the adenovirus origin of replication

1984 • 163 citations

The nucleotide sequence of the transforming HpaI-E fragment of adenovirus type 5 DNA

1978 • 157 citations

Recognition site of nuclear factor I, a sequence-specific DNA-binding protein from HeLa cells that stimulates adenovirus DNA replication.

1985 • 148 citations

Adenoviral control regions activated by E1A and the cAMP response element bind to the same factor.

1988 • 120 citations

The adenovirus type 5 E1A enhancer contains two functionally distinct domains: One is specific for E1A and the other modulates all early units in cis

1986 • 118 citations

An enhancer element is located 340 base pairs upstream from the adenovirus-2 E1A capsite

1983 • 116 citations

Promoter and enhancer elements containing a conserved sequence motif are recognized by nuclear factor III, a protein stimulating adenovirus DNA replication.

1987 • 110 citations

The TATA homology and the mRNA 5′ untranslated sequence are not required for expression of essential adenovirus E1A functions

1982 • 103 citations

Adenovirus origin of DNA replication: sequence requirements for replication in vitro.

1987 • 87 citations

Adenovinis DNA replicationin vitro: site-directed mutagenesis of the nuclear factor I binding site of the Ad2 origin

1985 • 80 citations

Sequence-Specific Interactions Between Cellular DNA-Binding Proteins and the Adenovirus origin of DNA Replication

1987 • 73 citations

Nucleotide Sequences of Adenovirus DNAs

1984 • 71 citations

Identification of proteins interacting with the enhancer of human U2 small nuclear RNA genes

1987 • 68 citations

Cellular transcription factor binds to adenovirus early region promoters and to a cyclic AMP response element

1988 • 63 citations

Identification of Two Transcription Factors That Bind to Specific Elements in the Promoter of the Adenovirus Early-Region 4

1988 • 57 citations

Adenovirus transforming 19-kD T antigen has an enhancer-dependent trans-activation function and relieves enhancer repression mediated by viral and cellular genes.

1987 • 48 citations

Two overlapping sequence motifs within the polyomavirus enhancer are independently the targets of stimulation by both the tumor promoter 12-O-tetradecanoylphorbol-13-acetate and the Ha-ras oncogene

1989 • 41 citations

Functional analysis of the nucleotide sequence surrounding the cap site for adenovirus type 5 region E1A messenger RNAs

1983 • 39 citations

Adenovirus Origin of DNA Replication: Sequence Requirements for Replication In Vitro

1987 • 33 citations

A cellular protein binds to a conserved sequence in the adenovirus type 2 enhancer

1987 • 21 citations

Transcription in the reverse orientation at either terminus of the adenovirus type 5 genome.

1989 • 18 citations