Structure of the 3’ Region of the Human Elastin Gene: Great Abundance of Alu Repetitive Sequences and Few Coding Sequences

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ

1977 • 4,696 citations

The isolation of structural genes from libraries of eucaryotic DNA

1978 • 1,877 citations

Synthesis of deoxyoligonucleotides on a polymer support

1981 • 870 citations

The Alu Family of Dispersed Repetitive Sequences

1982 • 611 citations

Base sequence studies of 300 nucleotide renatured repeated human DNA clones

1981 • 605 citations

The cross-linking of collagen and elastin: enzymatic conversion of lysine in peptide linkage to alpha-aminoadipic-delta-semialdehyde (allysine) by an extract from bone.

1968 • 488 citations

Mutation in LDL Receptor: Alu-Alu Recombination Deletes Exons Encoding Transmembrane and Cytoplasmic Domains

1985 • 453 citations

Isolation and Amino Acid Sequences of Tropoelastin Peptides

1973 • 269 citations

A versatile primer for DNA sequencing in the M13mp2 cloning system

1980 • 241 citations

Purification and partial characterization of a soluble elastin-like protein from copper-deficient procine aorta

1969 • 238 citations

Genome instability in a region of human DNA enriched in Alu repeat sequences

1982 • 220 citations

Conversion of RNA to DNA in mammals: Alu-like elements and pseudogenes

1983 • 202 citations

The Biosynthesis of Elastin Cross-links

1965 • 174 citations

Elastin

1963 • 169 citations

Viability of λ phages carrying a perfect palindrome in the absence of recombination nucleases

1983 • 166 citations

Identification of a new crosslinking amino acid in elastin

1965 • 135 citations

Propagation of some human DNA sequences in bacteriophage lambda vectors requires mutant Escherichia coli hosts.

1985 • 122 citations

A gene deletion ending at the midpoint of a repetitive DNA sequence in one form of hereditary persistence of fetal haemoglobin

1982 • 121 citations

Synthesis of elastin and procollagen by cells from embryonic aorta

1976 • 114 citations

Incorporation of Labelled Lysine into the Desmosine Cross-bridges in Elastin

1966 • 105 citations

Translation of chick aortic elastin messenger ribonucleic acid. Comparison to elastin synthesis in chick aorta organ culture

1980 • 96 citations

Isolation of soluble elastin from lathyritic chicks. Comparison to tropoelastin from copper deficient pigs

1975 • 92 citations

Mobility of elastin chains as determined by 13C nuclear magnetic resonance

1973 • 84 citations

Partial deletion of the α-globin structural gene in human α-thalassaemia

1980 • 77 citations

Isolation and translation of elastin mRNA from chick aorta

1979 • 76 citations

Correlation of functional elastin messenger ribonucleic acid levels and rate of elastin synthesis in the developing chick aorta

1980 • 73 citations

Regulation of elastin synthesis in developing sheep nuchal ligament by elastin mRNA levels.

1982 • 67 citations

Demonstration of a precursor-product relationship between soluble and cross-linked elastin, and the biosynthesis of the desmosines in vitro.

1976 • 64 citations

Modulation of tropoelastin production and elastin messenger ribonucleic acid activity in developing sheep lung

1981 • 61 citations

Demonstration of elastin gene expression in human skin fibroblast cultures and reduced tropoelastin production by cells from a patient with atrophoderma.

1985 • 56 citations

Biosynthesis and secretion of tropoelastin by chick aorta cells

1976 • 55 citations

Identification of a soluble intermediate during synthesis of elastin by embryonic chick aortae

1972 • 52 citations

Biosynthesis of Soluble Elastin by Pig Aortic Tissue in Vitro

1973 • 50 citations

Structure of the 3' portion of the bovine elastin gene

1985 • 49 citations

Characterization of molecular motions in ¹³C‐labeled aortic elastin by ¹³C‐¹H magnetic double resonance

1980 • 47 citations

Synthesis of elastin in aortas from chick embryos. Conversion of newly secreted elastin to cross-linked elastin without apparent proteolysis of the molecule

1977 • 44 citations

Chromosomal localization of the human elastin gene.

1985 • 44 citations

Characterization of a sheep elastin cDNA clone containing translated sequences

1984 • 40 citations

Analysis of elastin gene expression in the developing chick aorta using cloned elastin cDNA.

1982 • 40 citations

Primary structure of the signal peptide of tropoelastin b.

1981 • 39 citations

Analysis of the 3′ region of the sheep elastin gene

1985 • 37 citations

Sequencing of large double-stranded DNA using the dideoxy sequencing technique

1982 • 26 citations

Evidence that tropoelastin is the primary precursor in elastin biosynthesis.

1980 • 26 citations

Sheep elastin genes. Isolation and preliminary characterization of a 9.9-kilobase genomic clone

1984 • 20 citations