Sex-dependent Thermogenesis, Differences in Mitochondrial Morphology and Function, and Adrenergic Response in Brown Adipose Tissue

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUES

1957 • 63,238 citations

[45] Cytochrome oxidase from beef heart mitochondria

1967 • 1,268 citations

Ultrastructural Pathology of the Cell and Matrix

1988 • 808 citations

UCP1: the only protein able to mediate adaptive non-shivering thermogenesis and metabolic inefficiency

2001 • 573 citations

Brown adipose tissue thermogenesis: interdisciplinary studies

1990 • 462 citations

Mitochondrial uncoupling proteins: from mitochondria to the regulation of energy balance

2000 • 363 citations

Thermogenic Responses in Brown Fat Cells Are Fully UCP1-dependent

2000 • 323 citations

Ultrastructural Pathology of the Cell and Matrix

1988 • 268 citations

Ultrastructural Pathology of the Cell

1976 • 242 citations

Heterogeneous distribution of beta and alpha‐2 adrenoceptor binding sites in human fat cells from various fat deposits: functional consequences

1987 • 241 citations

The adipose organ: morphological perspectives of adipose tissues

2001 • 213 citations

Alpha- and beta-adrenergic induction of the expression of the uncoupling protein thermogenin in brown adipocytes differentiated in culture.

1990 • 204 citations

Obesity in Europe

1994 • 201 citations

Beta-adrenergic, cAMP-mediated stimulation of proliferation of brown fat cells in primary culture. Mediation via beta 1 but not via beta 3 adrenoceptors.

1992 • 189 citations

Testosterone Increases Lipolysis and the Number of β-Adrenoceptors in Male Rat Adipocytes*

1991 • 187 citations

Fat Cell α₂-Adrenoceptors: The Regulation of Fat CellFunction and Lipolysis*

1995 • 179 citations

Specific measurement of DNA in nuclei and nucleic acids using diaminobenzoic acid

1978 • 178 citations

Regulation of UCP1, UCP2, and UCP3 mRNA Expression in Brown Adipose Tissue, White Adipose Tissue, and Skeletal Muscle in Rats by Estrogen

2001 • 129 citations

Adrenergic regulation of adipocyte metabolism

1997 • 129 citations

Epididymal white adipose tissue after cold stress in rats II. Mitochondrial changes

1988 • 107 citations

Role of β₁- and β₃-adrenoceptors in the regulation of lipolysis and thermogenesis in rat brown adipocytes

1997 • 98 citations

Expression of Human α2-Adrenergic Receptors in Adipose Tissue of β3-Adrenergic Receptor-deficient Mice Promotes Diet-induced Obesity

2000 • 96 citations

Sex-associated differences in cold-induced UCP1 synthesis in rodent brown adipose tissue

1998 • 93 citations

Brown adipose tissue thermogenesis during aging and senescence.

1999 • 79 citations

Noradrenergic stimulation of mitochondriogenesis in brown adipocytes differentiating in culture

1987 • 70 citations

Differential adrenergic regulation of the gene expression of the β-adrenoceptor subtypes β1, β2 and β3 in brown adipocytes

2000 • 69 citations

Neural control of brown adipose tissue thermogenesis, hypertrophy, and atrophy

1991 • 68 citations

Sexual dimorphism in the adrenergic control of rat brown adipose tissue response to overfeeding

2001 • 67 citations

Brown adipose tissue response to cafeteria diet-feeding involves induction of the UCP2 gene and is impaired in female rats as compared to males

1999 • 57 citations

Evidence for masking of brown adipose tissue mitochondrial GDP-binding sites in response to fasting in rats made obese by dietary manipulation. Effects of reversion to standard diet

1991 • 55 citations

Postreceptor events involved in the up-regulation of beta-adrenergic receptor mediated lipolysis by testosterone in rat white adipocytes.

1993 • 50 citations

Biochemical and functional differences in rat liver mitochondrial subpopulations obtained at different gravitational forces

1996 • 50 citations

Gender Effects on Adrenergic Receptor Expression and Lipolysis in White Adipose Tissue of Rats

2002 • 48 citations

β‐Adrenoceptor subtype expression and function in rat white adipocytes

1997 • 47 citations

Influence of Ovariectomy and Regional Fat Distribution on the Membranous Transducing System Controlling Lipolysis in Rat Fat Cells*

1991 • 47 citations

Immunohistochemical, ultrastructural and morphometric evidence for brown adipose tissue recruitment due to cold acclimation in old rats.

1995 • 43 citations

Norepinephrine‐induced synthesis of the uncoupling protein thermogenin (UCP) and its mitochondrial targeting in brown adipocytes differentiated in culture

1990 • 43 citations

Modulation by sex hormones of the membranous transducing system regulating fatty acid mobilization in adipose tissue

1993 • 40 citations

Reduced norepinephrine turnover in interscapular brown adipose tissue of obese rats after ovariectomy

1987 • 39 citations

The oligosaccharide moiety of the .beta.1-adrenergic receptor from turkey erythrocytes has a biantennary, N-acetyllactosamine-containing structure

1985 • 38 citations

Effects of butyrate on ouabain-sensitive respiration of hamster brown adipocytes

1982 • 31 citations

Testosterone treatment of ovariectomized rats: Effects on lipolysis regulation in adipocytes

1990 • 31 citations

Noradrenaline induces brown adipocytes cell growth via ?-receptors by a mechanism dependent on ERKs but independent of cAMP and PKA

2000 • 26 citations

Influence of Age and Gender on Brown Adipose Tissue Norepinephrine Turnover

1993 • 22 citations

Reduced noradrenaline responsiveness of brown adipocytes isolated from estradiol-treated rats

1993 • 20 citations

Enhancement of the Expression of the α2-Adrenoreceptor Protein and mRNA by a Direct Effect of Androgens in White Adipocytes

1995 • 20 citations

Oestradiol and progesterone change beta3-adrenergic receptor affinity and density in brown adipocytes

2001 • 18 citations

Evidence that Testosterone Modulatesin Vivothe Adenylate Cyclase Activity in Fat Cells*

1990 • 18 citations

Dissociation between brown adipose tissue thermogenesis and sympathetic activity in rats with high plasma levels of oestradiol

1994 • 17 citations

Divergent effects of an α2-adrenergic antagonist on lipolysis and thermogenesis: Interactions with a β3-adrenergic agonist in rats

2001 • 15 citations

Rat preadipocyte adenylyl cyclase: influence of fat localization and androgenic status

1994 • 12 citations

Dual control of cytochrome-c oxidase activity by female sex steroids

1999 • 11 citations

Adipocyte α2A-adrenoceptor is the only α2-adrenoceptor regulated by testosterone

1994 • 8 citations