Different roles of α2-adrenoceptors of the medulla versus the spinal cord in modulation of mustard oil-induced central hyperalgesia in rats

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

The rat brain in stereotaxic coordinates

1983 • 28,962 citations

Endogenous Pain Control Systems: Brainstem Spinal Pathways and Endorphin Circuitry

1984 • 2,580 citations

Chronic catheterization of the spinal subarachnoid space

1976 • 2,244 citations

Characterization of the selectivity, specificity and potency of medetomidine as an α2-adrenoceptor agonist

1988 • 676 citations

Pharmacology of spinal adrenergic systems which modulate spinal nociceptive processing

1985 • 586 citations

Distribution of α2-adrenergic receptor subtype gene expression in rat brain

1994 • 423 citations

Spinal opioid analgesic effects are enhanced in a model of unilateral inflammation/hyperalgesia: possible involvement of noradrenergic mechanisms

1991 • 208 citations

Does neurogenic inflammation alter the sensitivity of unmyelinated nociceptors in the rat?

1986 • 160 citations

Spinal Antinociception by Dexmedetomidine, a Highly Selective α₂‐Adrenergic Agonist

1991 • 154 citations

Pain modulation by adrenergic agents and morphine as measured by three pain tests

1980 • 152 citations

Chapter 27 Pharmacologic evidence for the modulation of nociception by noradrenergic neurons

1988 • 149 citations

Characterization of inhibition of the spinal nociceptive tail-flick reflex in the rat from the medullary lateral reticular nucleus

1986 • 131 citations

Anatomical evidence for genetic differences in the innervation of the rat spinal cord by noradrenergic locus coeruleus neurons

1992 • 130 citations

The nucleus reticularis lateralis: A region highly sensitive to clonidine

1981 • 127 citations

Antinociception induced by alpha-2-adrenoceptor agonists, with special emphasis on medetomidine studies

1993 • 124 citations

Behavioural and neurochemical effects of antipamezole, a novel α2-adrenoceptor antagonist

1988 • 112 citations

Evidence for pain modulation by pre- and postsynaptic noradrenergic receptors in the medulla oblongata

1985 • 111 citations

Antinociceptive effects of intrathecal adrenoceptor agonists in a rat model of visceral nociception.

1990 • 96 citations

Comparison of the behavioral and neurochemical effects of the two optical enantiomers of medetomidine, a selective alpha-2-adrenoceptor agonist.

1991 • 78 citations

Behavioural and neurochemical effects of atipamezole, a novel α2-adreneceptor antagonist

1988 • 75 citations

Antinociceptive properties of intrathecal dexmedetomidine in rats

1991 • 70 citations

Descending projections from the caudal medulla oblongata to the superficial or deep dorsal horn of the rat spinal cord

1994 • 69 citations

Dissociation of the α 2-adrenergic antinociception from sedation following microinjection of medetomidine into the locus coeruleus in rats

1994 • 55 citations

Spinal monoaminergic receptors mediate the antinociception produced by glutamate in the medullary lateral reticular nucleus

1987 • 53 citations

Alpha-2 adrenergic receptors on neurones in the region of the lateral reticular nucleus of the rat

1983 • 50 citations

Opioid, cholinergic and α-adrenergic influences on the modulation of nociception from the lateral reticular nucleus of the rat

1986 • 49 citations

The depressive effect of intrathecal clonidine on the spinal flexor reflex is enhanced after sciatic nerve section in rats

1992 • 49 citations

Enhanced alpha-2 adrenergic controls and spinal morphine potency in inflammation

1994 • 43 citations

Antinociceptive effects of intrathecal administration of α-adrenoceptor antagonists and clonidine in the formalin test in the mouse

1993 • 39 citations

Potent antinociceptive effects of clonidine systemically administered in an experimental model of clinical pain, the arthritic rat

1992 • 37 citations

Antinociceptive actions of dexmedetomidine and the kappa-opioid agonist U-50,488H against noxious thermal, mechanical and inflammatory stimuli.

1994 • 33 citations

Antagonism of alpha-adrenoceptor agonist-induced antinociception in the rat

1986 • 29 citations

α-Adrenergic receptor agonists, but not antagonists, alter the tail-flick latency when microinjected into the rostral ventromedial medulla of the lightly anesthetized rat

1990 • 29 citations

Influence of selective α2-adrenergic agents on mustard oil-induced central hyperalgesia in rats

1995 • 25 citations

The antinociceptive action of an α2-adrenoceptor agonist in the spinal dorsal horn is due to a direct spinal action and not to activation of Descending Inhibition

1995 • 23 citations

Yohimbine both increases and decreases nociceptive thresholds in rats: Evaluation of the dose-response relationship

1983 • 23 citations

Spinal Potentiation and Supraspinal Additivity in the Antinociceptive Interaction Between Systemically Administered ??2-Adrenoceptor Agonist and Cocaine in the Rat

1994 • 21 citations

Selective blockade by yohimbine of descending spinal inhibition from lateral reticular nucleus but not from locus coeruleus in rats

1992 • 20 citations

The role of α2-adrenoceptors of the medullary lateral reticular nucleus in spinal antinociception in rats

1995 • 17 citations

The rostroventromedial medulla is not involved in α2-adrenoceptor-mediated antinociception in the rat

1993 • 13 citations