Targeted Disruption of Murine Organic Anion-Transporting Polypeptide 1b2 (oatp1b2/Slco1b2) Significantly Alters Disposition of Prototypical Drug Substrates Pravastatin and Rifampin

Organic anion transporting polypeptides of the OATP/ SLC21 family: phylogenetic classification as OATP/ SLCO superfamily, new nomenclature and molecular/functional properties

2004 • 976 citations

A Novel Human Hepatic Organic Anion Transporting Polypeptide (OATP2)

1999 • 630 citations

A novel human organic anion transporting polypeptide localized to the basolateral hepatocyte membrane

2000 • 611 citations

Drug and Bile Acid Transporters in Rosuvastatin Hepatic Uptake: Function, Expression, and Pharmacogenetics

2006 • 585 citations

Identification of a Novel Gene Family Encoding Human Liver-specific Organic Anion Transporter LST-1

1999 • 546 citations

Transporters and drug therapy: Implications for drug disposition and disease

2005 • 497 citations

Interactions of rifamycin SV and rifampicin with organic anion uptake systems of human liver

2002 • 369 citations

LST-2, A human liver-specific organic anion transporter, determines methotrexate sensitivity in gastrointestinal cancers

2001 • 338 citations

Human Organic Anion Transporting Polypeptide-C (SLC21A6) Is a Major Determinant of Rifampin-Mediated Pregnane X Receptor Activation

2003 • 325 citations

CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice

2005 • 324 citations

Impaired Organic Anion Transport in Kidney and Choroid Plexus of Organic Anion Transporter 3 (Oat3 (Slc22a8)) Knockout Mice

2002 • 284 citations

Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated mice

2003 • 258 citations

Reduced Hepatic Uptake and Intestinal Excretion of Organic Cations in Mice with a Targeted Disruption of the Organic Cation Transporter 1 (Oct1 [Slc22a1]) Gene

2001 • 223 citations

Decreased Renal Organic Anion Secretion and Plasma Accumulation of Endogenous Organic Anions in OAT1 Knock-out Mice

2005 • 223 citations

Human liver-specific organic anion transporter, LST-1, mediates uptake of pravastatin by human hepatocytes.

2001 • 211 citations

Effect of drug transporter genotypes on pravastatin disposition in European- and African-American participants

2007 • 193 citations

CONTRIBUTION OF OATP (ORGANIC ANION-TRANSPORTING POLYPEPTIDE) FAMILY TRANSPORTERS TO THE HEPATIC UPTAKE OF FEXOFENADINE IN HUMANS

2005 • 180 citations

Coordinated induction of bile acid detoxification and alternative elimination in mice: role of FXR-regulated organic solute transporter-α/β in the adaptive response to bile acids

2005 • 171 citations

Organic Anion-Transporting Polypeptides

2014 • 170 citations

Identification of organic anion transporting polypeptide 4 (Oatp4) as a major full-length isoform of the liver-specific transporter-1 (rlst-1) in rat liver

2000 • 144 citations

Pharmacogenomics of the OATP and OAT Families

2004 • 126 citations

Full-Length cDNA Cloning and Genomic Organization of the Mouse Liver-Specific Organic Anion Transporter-1 (lst-1)

2000 • 44 citations

Cloning of the Full-Length Coding Sequence of Rat Liver-Specific Organic Anion Transporter-1 (rlst-1) and a Splice Variant and Partial Characterization of the Rat lst-1 Gene

2000 • 39 citations

Expression and Regulation of Breast Cancer Resistance Protein and Multidrug Resistance Associated Protein 2 in BALB/c Mice

2006 • 24 citations

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