Solid phase peptide synthesis of lipopeptide vaccines eliciting epitope‐specific B‐, T‐helper and T‐killer cell response

Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules

1991 • 2,447 citations

Synthetic peptide vaccine design: synthesis and properties of a high-density multiple antigenic peptide system.

1988 • 1,241 citations

Antigen Recognition by Class I-Restricted T Lymphocytes

1989 • 1,207 citations

Identification of self peptides bound to purified HLA-B27

1991 • 844 citations

Isolation and analysis of naturally processed viral peptides as recognized by cytotoxic T cells

1990 • 775 citations

Isolation of an endogenously processed immunodominant viral peptide from the class I H–2Kb molecule

1990 • 689 citations

The structure of HLA-B27 reveals nonamer self-peptides bound in an extended conformation

1991 • 687 citations

In vivo priming of virus-specific cytotoxic T lymphocytes with synthetic lipopeptide vaccine

1989 • 632 citations

Covalent lipoprotein from the outer membrane of escherichia coli

1975 • 568 citations

The lipoprotein of the outer membrane of Escherichia coli: a B-lymphocyte mitogen.

1975 • 273 citations

Synthetic lipopeptide analogs of bacterial lipoprotein are potent polyclonal activators for murine B lymphocytes.

1985 • 174 citations

Naturally-occurring peptide antigens derived from the MHC class-I-restricted processing pathway

1991 • 171 citations

Synthesis of the Mitogenic S-[2,3-Bis(palmitoyloxy)propyl]-N-palmitoylpentapeptide fromEscherichia coliLipoprotein

1983 • 149 citations

Efficiency of peptides and lipopeptides for in vivo priming of virus‐specific cytotoxic T cells

1991 • 141 citations

Novel low-molecular-weight synthetic vaccine against foot-and-mouth disease containing a potent B-cell and macrophage activator

1989 • 140 citations

Stimulation of Human and Murine Adherent Cells by Bacterial Lipoprotein and Synthetic Lipopeptide Analogues

1988 • 116 citations

Methoden der multiplen Peptidsynthese und ihre Anwendungen

1992 • 92 citations

Activation of bone marrow‐derived mouse macrophages by bacterial lipopeptide: cytokine production, phagocytosis and Ia expression

1990 • 86 citations

Lipopeptide Derivatives of Bacterial Lipoprotein Constitute Potent Immune Adjuvants Combined with or Covalently Coupled to Antigen or Hapten

1989 • 82 citations

Synthesis of novel immunologically active tripalmitoyl‐S‐glycerylcysteinyl lipopeptides as useful intermediates for immunogen preparations

1991 • 81 citations

A synthetic analogue of Escherichia coli lipoprotein, tripalmitoyl pentapeptide, constitutes a potent immune adjuvant.

1986 • 74 citations

Lipopeptides of the N-terminus of Escherichia coli lipoprotein: synthesis, mitogenicity and properties in monolayer experiments

1987 • 69 citations

Synthesis of N_α‐Fmoc protected derivatives of S‐(2,3‐dihydroxypropyl)‐cysteine and their application in peptide synthesis

1991 • 60 citations

Lipopeptides containing 2-(palmitoylamino)-6,7-bis(palmitoyloxy)heptanoic acid: synthesis, stereospecific stimulation of B-lymphocytes and macrophages and adjuvanticity in vivo and in vitro

1991 • 58 citations

Induction of Tumor Cytotoxicity in Murine Bone Marrow-Derived Macrophages by Two Synthetic Lipopeptide Analogues

1989 • 58 citations

Histopathological studies on the local reactions induced by complete fReund's adjuvant (CFA), bacterial lipopolysaccharide (LPS), and synthetic lipopeptide (P₃C) conjugates

1991 • 55 citations

Development of artificial vaccines against HIV using defined epitopes

1991 • 48 citations

Activation of superoxide formation and lysozyme release in human neutrophils by the synthetic lipopeptide Pam3Cys-Ser-(Lys)4. Involvement of guanine-nucleotide-binding proteins and synergism with chemotactic peptides

1990 • 42 citations

Lymphocyte Activation and Differentiation

1988 • 41 citations

Interaction of mitogenic bacterial lipoprotein and a synthetic analogue with mouse lymphocytes

1987 • 40 citations

Verstärkte Produktion spezifischer Antikörper durch Präsentation der antigenen Determinanten mit kovalent verknüpften Lipopeptid‐Mitogenen

1985 • 27 citations

Conjugates of Synthetic Lymphocyte-Activating Lipopeptides with Segments from HIV Proteins Induce Protein-Specific Antibody Formation

1990 • 25 citations

Preparation of human and murine monoclonal antibodies: antigens combined with or conjugated to lipopeptides constitute potent immunogens for in vitro and in vivo immunizations

1990 • 25 citations

Activation of Lymphocyte Populations with Concanavalin A or with Lipoprotein and Lipopeptide from the Outer Cell Wall of Escherichia coli Correlation of Early Membrane Changes with Induction of Macromolecular Synthesis

1981 • 25 citations

Intracellular Localization of a Lipopeptide Macrophage Activator: Immunocytochemical Investigations and EELS Analysis on Ultrathin Cryosections of Bone Marrow-Derived Macrophages

1991 • 21 citations

Incomplete functional differentiation of HL‐60 leukemic cells by synthetic lipopetides

1992 • 21 citations

Rapid alterations in the plasma membrane structure of macrophages stimulated with bacterial lipopeptides.

1992 • 21 citations

Enhancement of Protection against Salmonella Infection in Mice Mediated by a Synthetic Lipopeptide Analogue of Bacterial Lipoprotein in S. typhimurium Vaccines

1989 • 20 citations

Interaction of the Lymphoid Cell Line BCL1 with Lipopeptide Analogues of Bacterial Lipoprotein: Electron Energy Loss Spectroscopy (EELS) as a Novel Method to Detect the Distribution of the Activator within the Cells

1989 • 18 citations

The antibody response in BALB/c mice to the Plasmodium falciparum circumsporozoite repetitive epitope covalently coupled to synthetic lipopeptide adjuvant.

1991 • 17 citations

Ionenspray-Massenspektrometrie von Lipopeptid-Vaccinen

1992 • 14 citations

Synthesis of a B-Lymphocyte Activating α-Methylserine Containing Lipopentapeptide

1987 • 13 citations

Bacterial Surface Components as Immunomodulators

1990 • 12 citations

Increase in the intracellular free calcium concentration is not an obligatory early event in lipopeptide-induced B-cell activation.

1991 • 4 citations