Finasteride

Transurethral Prostatectomy: Immediate and Postoperative Complications. A Cooperative Study of 13 Participating Institutions Evaluating 3,885 Patients

1989 • 1,430 citations

Steroid 5α-Reductase Deficiency in Man: An Inherited Form of Male Pseudohermaphroditism

1974 • 1,241 citations

The Effect of Finasteride in Men with Benign Prostatic Hyperplasia

1992 • 1,111 citations

The Conversion of Testosterone to 5α-Androstan-17β-ol-3-one by Rat Prostate in Vivo and in Vitro

1968 • 1,023 citations

Mortality and Reoperation after Open and Transurethral Resection of the Prostate for Benign Prostatic Hyperplasia

1989 • 670 citations

Etiology and disease process of benign prostatic hyperplasia

1989 • 557 citations

Selective Retention of Dihydrotestosterone by Prostatic Nuclei

1968 • 532 citations

Origin and evolution of benign prostatic enlargement.

1978 • 530 citations

Symptom Status and Quality of Life Following Prostatectomy

1988 • 442 citations

Molecular genetics of steroid 5 alpha-reductase 2 deficiency.

1992 • 414 citations

Genetic and pharmacological evidence for more than one human steroid 5 alpha-reductase.

1992 • 395 citations

Testosterone: A Major Determinant of Extragenital Sexual Dimorphism

1981 • 391 citations

Male pseudohermaphroditism due to steroid 5α-reductase deficiency

1977 • 390 citations

Finasteride, an inhibitor of 5 alpha-reductase, suppresses prostatic dihydrotestosterone in men with benign prostatic hyperplasia.

1992 • 306 citations

Copulation in Castrated Male Rats following Combined Treatment with Estradiol and Dihydrotestosterone

1973 • 292 citations

A Placebo‐controlled Double‐blind Study of the Effect of Phenoxybenzamine in Benign Prostatic Obstruction

1978 • 275 citations

Watchful Waiting vs Immediate Transurethral Resection for Symptomatic Prostatism

1988 • 273 citations

The Present Role of Alpha-Adrenergic Blockers in the Treatment of Benign Prostatic Hypertrophy

1986 • 260 citations

Azasteroids: structure-activity relationships for inhibition of 5.alpha.-reductase and of androgen receptor binding

1986 • 252 citations

Prazosin in the Treatment of Prostatic Obstruction A Placebo‐controlled Study

1987 • 226 citations

Alpha-Adrenergic Activity and Urethral Pressure in Prostatic Zone in Benign Prostatic Hypertrophy

1982 • 225 citations

A new look at bladder neck obstruction by the food and drug administration regulators: guide lines for investigation of benign prostatic hypertrophy.

1976 • 223 citations

Sex Steroids in the Umbilical Circulation of Fetal Rhesus Monkeys from the Time of Gonadal Differentiation*

1980 • 211 citations

Species Differences in Prostatic Steroid 5α-Reductases of Rat, Dog, and Human

1985 • 200 citations

The Efficacy of Transurethral Resection of the Prostate in Men with Moderate Symptoms of Prostatism

1990 • 189 citations

Finasteride (MK‐906) in the treatment of benign prostatic hyperplasia

1993 • 170 citations

The Clinical Effects of a 5α-Reductase Inhibitor, Finasteride, on Benign Prostatic Hyperplasia

1992 • 168 citations

Effects of Finasteride (MK-906), a 5α-Reductase Inhibitor, on Circulating Androgens in Male Volunteers*

1990 • 163 citations

Nonoperative Management of Benign Prostatic Hyperplasia

1989 • 153 citations

Effects of Flutamide and Finasteride on Rat Testicular Descent

1991 • 150 citations

Natural history of benign prostatic hypertrophy and acute urinary retention

1976 • 143 citations

Effect of Finasteride, a 5α-Reductase Inhibitor on Prostate Tissue Androgens and Prostate-Specific Antigen*

1990 • 136 citations

The effect of finasteride on prostate‐specific antigen in men with benign prostatic hyperplasia

1993 • 133 citations

External genitalia abnormalities in male rats exposed in utero to finasteride, a 5α‐reductase inhibitor

1990 • 127 citations

Anatomy of the prostate and morphogenesis of BPH.

1984 • 111 citations

Alfuzosin

1993 • 107 citations

Hormonal effects of an orally active 4‐azasteroid inhibitor of 5α‐reductase in humans

1989 • 105 citations

4-Azasteroidal 5 alpha-reductase inhibitors without affinity for the androgen receptor.

1984 • 104 citations

5α-Reductase inhibitory and anti-androgenic activities of some 4-azasteroids in the rat

1986 • 94 citations

The Effect of a 5α-Reductase Inhibitor on Androgen Physiology in the Immature Male Rat*

1989 • 94 citations

Natural History of Benign Prostatic Hypertrophy

1983 • 84 citations

Effect of MK‐906, a Specific 5α‐reductase Inhibitor, on Serum Androgens and Androgen Conjugates in Normal Men

1989 • 82 citations

The influence of finasteride on the volume of the peripheral and periurethral zones of the prostate in men with benign prostatic hyperplasia

1993 • 81 citations

Goserelin

1991 • 78 citations

Inhibition of Testosterone Conversion to Dihydrotestosterone in Men Treated Percutaneously by Progesterone

1974 • 78 citations

Androgen Ablation and Blockade in the Treatment of Benign Prostatic Hyperplasia

1990 • 78 citations

Prostatic effects induced in dogs by chronic or acute oral administration of 5α‐reductase inhibitors

1986 • 73 citations

Effect of finasteride, a 5 alpha-reductase inhibitor, on serum gonadotropins in normal men.

1992 • 69 citations

Validation of a symptoms questionnaire for benign prostatic hyperplasia

1992 • 64 citations

Disposition and pharmacokinetics of [14C]finasteride after oral administration in humans.

1992 • 64 citations

BPH epidemiology and risk factors

1989 • 64 citations

Medical management of benign prostatic hyperplasia with androgen suppression

1990 • 61 citations

Terazosin

1993 • 61 citations

Pharmacokinetics and biochemical efficacy after single and multiple oral administration of N-(2-methyl-2-propyl)-3-oxo-4-aza-5α-androst-1-ene-17β-carboxamide, a new type of specific competitive inhibitor of testosterone 5α-reductase, in volunteers

1991 • 59 citations

Differential Effect of 5α-Reductase Inhibition and Castration on Androgen-Regulated Gene Expression in Rat Prostate

1991 • 57 citations

C₁₉and C₂₁5β/5αMetabolite Ratios in Subjects Treated with the 5α-Reductase Inhibitor Finasteride: Comparison of Male Pseudohermaphrodites with Inherited 5α-Reductase Deficiency*

1990 • 57 citations

Leuprorelin

1991 • 55 citations

Sexual Differentiation: Early Hormone Synthesis and Action1

1980 • 53 citations

Natural history of benign prostatic hypertrophy

1986 • 52 citations

Prolonged treatment with finasteride (a 5α‐reductase inhibitor) does not affect bone density and metabolism

1992 • 52 citations

Urodynamic and Histological Correlates of Benign Prostatic Hyperplasia

1988 • 49 citations

Clinical experience: symptomatic management of BPH with terazosin.

1988 • 47 citations

Nafarelin

1990 • 46 citations

Finasteride in the Treatment of Benign Prostatic Hyperplasia. A Urodynamic Evaluation

1992 • 46 citations

Scandinavian Clinical Study of Finasteride in the Treatment of Benign Prostatic Hyperplasia

1992 • 46 citations

EFFECTS OF ANDROGENIC AND OESTROGENIC HORMONES ON MATING BEHAVIOUR IN RAMS CASTRATED BEFORE OR AFTER PUBERTY

1980 • 44 citations

The steroid 5α-reductase activity of rat liver and prostate

1971 • 43 citations

Diagnostic assessment of benign prostatic hyperplasia

1989 • 39 citations

Critical evaluation of transurethral resection and incision of the prostate

1990 • 38 citations

Pathogenesis and medical treatment of benign prostatic hyperplasia

1989 • 37 citations

Pathogenesis of Benign Prostatic Hyperplasia

1991 • 32 citations

Hormonal effects, tolerability, and preliminary kinetics in men of MK-906, a 5α-reductase inhibitor

1991 • 29 citations

Serum prostate-antigen levels in patients with benign prosttic hypertrophy treated with leuprolide

1989 • 29 citations

High-performance liquid chromatographic determination of N-(2-methyl-2-propyl)-3-oxo-4-aza-5α-androst-1-ene-17β-carboxamide, a 4-azasteroid, in human plasma from a phase I study

1988 • 25 citations

High-performance liquid chromatographic method for the determination of finasteride in human plasma at therapeutic doses

1991 • 24 citations

Magnetic resonance imaging of the efficacy of specific inhibition of 5α‐reductase in canine spontaneous benign prostatic hyperplasia

1991 • 23 citations

The safety and efficacy of terazosin for the treatment of benign prostatic hyperplasia.

1989 • 20 citations

Alpha-adrenoceptor inhibitors in the treatment of benign prostatic hyperplasia

1989 • 19 citations

Natural history of benign prostatic hyperplasia (BPH)

1989 • 19 citations

Urodynamic Results of Surgery

1983 • 17 citations

Surgical management for benign prostatic hyperplasia: Indications, techniques, and results

1989 • 16 citations

Mechanism of Thyroxine-induced Increase in Steroid Δ⁴-Reductase Actiyity in Male Rats

1970 • 12 citations

One-year experience in the treatment of benign prostatic hyperplasia with finasteride. The MK-906 (Finasteride) Study Group.

1991 • 7 citations

Medical and nonmedical therapies for benign prostatic hypertrophy.

1991 • 5 citations

Medical and nonmedical therapies for benign prostatic hypertrophy.

1991 • 4 citations

Review of current and future approaches to the management of benign prostatic hyperplasia

1992 • 4 citations

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