Fluorescence spectroscopic investigations of the dynamic properties of proteins, membranes and nucleic acids

The Fluid Mosaic Model of the Structure of Cell Membranes

1972 • 8,835 citations

Quenching of fluorescence by oxygen. Probe for structural fluctuations in macromolecules

1973 • 2,653 citations

Exposure of tryptophanyl residues in proteins. Quantitative determination by fluorescence quenching studies

1976 • 1,020 citations

The interpretation of protein structures: Total volume, group volume distributions and packing density

1974 • 906 citations

Design of Liposomes for Enhanced Local Release of Drugs by Hyperthermia

1978 • 896 citations

Phase transitions and fluidity characteristics of lipids and cell membranes

1975 • 774 citations

Quenching of protein fluorescence by oxygen. Detection of structural fluctuations in proteins on the nanosecond time scale

1973 • 774 citations

Fluorescence depolarization studies of phase transitions and fluidity in phospholipid bilayers. 2. Two-component phosphatidylcholine liposomes

1976 • 758 citations

Polarization of the fluorescence of macromolecules. 1. Theory and experimental method

1952 • 673 citations

Fluorescence quenching of indole and model micelle systems

1976 • 613 citations

Polarization of the fluorescence of macromolecules. 2. Fluorescent conjugates of ovalbumin and bovine serum albumin

1952 • 606 citations

MEASUREMENTS OF SUBNANOSECOND FLUORESCENCE LIFETIMES WITH A CROSS‐CORRELATION PHASE FLUOROMETER*

1969 • 600 citations

Microviscosity and order in the hydrocarbon region of micelles and membranes determined with fluorescent probes. I. Synthetic micelles

1971 • 552 citations

Segmental flexibility in an antibody molecule

1970 • 465 citations

Surface density determination in membranes by fluorescence energy transfer

1978 • 422 citations

Dynamic structure of lipid bilayers studied by nanosecond fluorescence techniques

1977 • 421 citations

Fluorescence depolarization studies of phase transitions and fluidity in phospholipid bilayers. 1. Single component phosphatidylcholine liposomes

1976 • 378 citations

Microviscosity and order in the hydrocarbon region of phospholipid and phospholipid-cholesterol dispersions determined with fluorescent probes

1973 • 361 citations

Differential polarized phase fluorometric investigations of diphenylhexatriene in lipid bilayers. Quantitation of hindered depolarizing rotations

1979 • 333 citations

THERMOTROPIC TRANSITIONS IN BIOMEMBRANES

1976 • 333 citations

Nanosecond time-dependent fluorescence depolarization of diphenylhexatriene in dimyristoyllecithin vesicles and the determination of "microviscosity".

1977 • 300 citations

Pyrene. Probe of lateral diffusion in the hydrophobic region of membranes

1974 • 297 citations

Exposure of tryptophanyl residues and protein dynamics

1977 • 287 citations

Rotational relaxation of the “microviscosity” probe diphenylhexatriene in paraffin oil and egg lecithin vesicles.

1977 • 238 citations

Brownian motion of the ends of oligopeptide chains in solution as estimated by energy transfer between the chain ends

1978 • 233 citations

Interaction of hemoglobin with red blood cell membranes as shown by a fluorescent chromophore

1977 • 232 citations

Intramolecular distances determined by energy transfer. Dependence on orientational freedom of donor and acceptor

1974 • 226 citations

Enzyme Dynamics: The Statistical Physics Approach

1979 • 220 citations

Statistical Time Events in Enzymes: A Physical Assessmen

1975 • 194 citations

Charge-Transfer Complex and Solvent-Shared Ion Pair in Fluorescence Quenching

1967 • 174 citations

Fluorescence-polarization spectrum and electronic-energy transfer in proteins

1960 • 169 citations

Theory of differential phase fluorometry: Detection of anisotropic molecular rotations

1977 • 164 citations

Electronic processes in hetero-excimers and the mechanism of fluorescence quenching

1967 • 161 citations

Effect of cholesterol on the molecular motion in the hydrocarbon region of lecithin bilayers studied by nanosecond fluorescence techniques

1978 • 144 citations

Fluorescence depolarization of rabbit gamma globulin conjugates

1967 • 139 citations

Nanosecond time-resolved emission spectroscopy of a fluorescence probe adsorbed to L-alpha-egg lecithin vesicles

1976 • 134 citations

Degree of exposure of membrane proteins determined by fluorescence quenching

1977 • 125 citations

Fluorescence quenching by the stable free radical di-t-butylnitroxide

1973 • 123 citations

Rotational anisotropy and solvent–fluorophore bonds: An investigation by differential polarized phase fluorometry

1977 • 120 citations

Nanosecond Time-resolved Fluorescence Spectra of a Protein-Dye Complex

1971 • 116 citations

Conformational studies on transfer ribonucleic acid. Fluorescence lifetime and nanosecond depolarization measurements on bound ethidium bromide

1970 • 115 citations

Fluorescence anisotropy measurements under oxygen quenching conditions as a method to quantify the depolarizing rotations of fluorophores. Application to diphenylhexatriene in isotropic solvents and in lipid bilayers

1979 • 113 citations

Quantitation of Hindered Rotations of Diphenylhexatriene in Lipid Bilayers by Differential Polarized Phase Fluorometry

1978 • 105 citations

Time-resolved nanosecond emission spectroscopy: spectral shift due to solvent-solute relaxation

1968 • 104 citations

Permeability of Lipid Bilayer Membranes to Organic Solutes

1968 • 103 citations

Conformation of the anticodon loop of phenylalanine transfer ribonucleic acid. Effect of environment on the fluorescence of the Y base

1970 • 97 citations

Nanosecond decay studies of a fluorescence probe bound to apomyoglobin

1977 • 92 citations

High Performance Phase Fluorometer Constructed from Commercial Subunits

1965 • 88 citations

Mesure de la décroissance de la fluorescence polarisée de la γ-globuline-1-sulfonyl-5-diméthylaminonaphtalène

1969 • 87 citations

Fast relaxation processes in a protein revealed by the decay kinetics of tryptophan fluorescence

1974 • 87 citations

Effect of phase transition on the kinetics of dye transport in phospholipid bilayer structures

1975 • 84 citations

A Study on the Motion Of Protenis in Excitable Membrane Fragment by Nanosecond Fluorescence Polarization Spectroscopy

1971 • 82 citations

Diffusion and patching of macromolecules on planar lipid bilayer membranes

1977 • 79 citations

Applications of Fluorescence Correlation Spectroscopy

1976 • 77 citations

Lateral diffusion of a hydrophobic peptide, N4-nitrobenz-2-oxa-1,3-diazole gramicidin S, in phospholipid multibilayers

1978 • 77 citations

Effect of cholesterol on the rotational mobility of diphenylhexatriene in liposomes: A nanosecond fluorescence anisotropy study

1977 • 77 citations

Properties of benzopyrene-DNA complexes investigated by fluorescence and triplet flash photolysis techniques

1976 • 70 citations

Excited state solvation dynamics of 2-anilinonaphthalene

1977 • 68 citations

Diffusion and partitioning of a pesticide, lindane, into phosphatidylcholine bilayers

1977 • 67 citations

Fluorescence Polarization of Human γG-Immunoglobulins^*

1967 • 66 citations

Effect of Diffusion on Transfer of Electronic Excitation Energy

1968 • 61 citations

A method for measuring membrane microviscosity using pyrene excimer formation. Application to human erythrocyte ghosts

1979 • 55 citations

Nanosecond relaxation processes in liposomes

1978 • 49 citations

Mesures des declins de l'anisotropie de fluorescence de la gamma-globuline et de ses fragments Fab, Fc et F(ab)2 marques avec le l-sulfonyl-5-dimethyl-aminonaphtalene

1972 • 47 citations

Excited states of biological molecules

1977 • 47 citations

Depolarization of the intrinsic and extrinsic fluorescence of pepsinogen and pepsin

1970 • 47 citations

LUMINESCENCE SPECTRA OF NAPHTHOLS AND NAPHTHALENEDIOLS: LOW-TEMPERATURE PHENOMENA¹

1960 • 45 citations

Subanosecond solvent relaxation studies by oxygen quenching of fluorescence

1973 • 39 citations

Exciplex photophysics. III. Kinetics of fluorescence quenching of .alpha.-cyanonaphthalene by dimethylcyclopentene-1,2 in hexane

1976 • 33 citations

Evidence for a conformational change in the Escherichia coli maltose receptor by excited-state fluorescence lifetime data

1979 • 32 citations

Fluorescence measurements of environmental relaxation at the lipid-water interface region of bilayer membranes

1978 • 31 citations

Fluorescence energy transfer measurements between ligand binding sites of the pyruvate dehydrogenase multienzyme complex

1976 • 27 citations

Construction of a Nanosecond Fluorometric System for Applications to Biological Samples at Cell or Tissue Levels

1976 • 24 citations

Energy transfer and dynamical structure

1976 • 19 citations

Fluorometric Study of the Effect of Solvent on the Fluorescence Spectrum of 3-Amino-N-Methylphthalimide

1965 • 19 citations

EFFECT OF SOLVENT VISCOSITY ON EXCITATION ENERGY TRANSFER BETWEEN UNLIKE MOLECULES

1963 • 18 citations

Nanosecond relaxation in membranes observed by fluorescence lifetime-resolved emission spectra.

1979 • 5 citations