Disruption of the β subunit of the epithelial Na ⁺ channel in mice: Hyperkalemia and neonatal death associated with a pseudohypoaldosteronism phenotype

Current protocols in molecular biology

1988 • 4,543 citations

Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits

1994 • 1,943 citations

Liddle's syndrome: Heritable human hypertension caused by mutations in the β subunit of the epithelial sodium channel

1994 • 1,238 citations

Epithelial sodium channels: function, structure, and regulation

1997 • 1,154 citations

An Animal Model for Cystic Fibrosis Made by Gene Targeting

1992 • 921 citations

Epithelial sodium channel related to proteins involved in neurodegeneration

1993 • 911 citations

Early death due to defective neonatal lung liquid clearance in αENaC-deficient mice

1996 • 873 citations

Mutations in subunits of the epithelial sodium channel cause salt wasting with hyperkalaemic acidosis, pseudohypoaldosteronism type 1

1996 • 794 citations

Mechanism by which Liddle's syndrome mutations increase activity of a human epithelial Na+ channel

1995 • 408 citations

Expression cloning of an epithelial amiloride‐sensitive Na⁺ channel

1993 • 340 citations

Membrane topology of the epithelial sodium channel in intact cells

1994 • 311 citations

A mutation in the epithelial sodium channel causing Liddle disease increases channel activity in the Xenopus laevis oocyte expression system.

1995 • 304 citations

Molecular Cloning and Functional Expression of a Novel Amiloride-sensitive Na+ Channel

1995 • 298 citations

A mouse model for the delta F508 allele of cystic fibrosis.

1995 • 294 citations

A novel spice–site mutation in the γ subunit of the epithelial sodium channel gene in three pseudohypoaldosteronism type 1 families

1996 • 241 citations

Cloning and expression of the beta- and gamma-subunits of the human epithelial sodium channel

1995 • 234 citations

Membrane topology of the amiloride-sensitive epithelial sodium channel.

1994 • 220 citations

Biochemical analysis of the membrane topology of the amiloride-sensitive Na+ channel.

1994 • 219 citations

Lung epithelial Na channel subunits are differentially regulated during development and by steroids

1995 • 199 citations

A mouse model for the renal salt-wasting syndrome pseudohypoaldosteronism

1997 • 167 citations

Cloning, expression, and tissue distribution of a human amiloride-sensitive Na+ channel

1994 • 158 citations

Structure and function of amiloride-sensitive Na+ channels

1995 • 149 citations

Biophysical and molecular properties of amiloride-inhibitable Na+ channels in alveolar epithelial cells

1996 • 147 citations

Preservation of structural and functional polarity in isolated epithelial cells

1996 • 118 citations

Molecular biology of Na+ absorption

1997 • 100 citations

Apical Na+ conductance in maturing rabbit principal cell

1996 • 93 citations

An essential role of myosin light‐chain kinase in the regulation of agonist‐ and fluid flow‐stimulated Ca²⁺influx in endothelial cells

1998 • 78 citations

Postnatal maturation of potassium transport in rabbit cortical collecting duct

1994 • 78 citations

Structure and function of the Mec-ENaC family of ion channels.

1998 • 61 citations

Ion transport by the collecting duct.

1993 • 37 citations