Genetically Programmed Biases in Th1 and Th2 Immune Responses Modulate Atherogenesis

C-Reactive Protein and Other Markers of Inflammation in the Prediction of Cardiovascular Disease in Women

2000 • 5,760 citations

Functional diversity of helper T lymphocytes

1996 • 4,512 citations

Acquisition of Lymphokine-Producing Phenotype by CD4+ T Cells

1994 • 1,573 citations

Autoantibody against oxidised LDL and progression of carotid atherosclerosis

1992 • 1,332 citations

Cytokine expression in advanced human atherosclerotic plaques: dominance of pro-inflammatory (Th1) and macrophage-stimulating cytokines

1999 • 987 citations

T lymphocytes from human atherosclerotic plaques recognize oxidized low density lipoprotein.

1995 • 945 citations

Reduction of atherosclerosis in mice by inhibition of CD40 signalling

1998 • 917 citations

IFN-gamma potentiates atherosclerosis in ApoE knock-out mice.

1997 • 855 citations

Protective Role of Interleukin-10 in Atherosclerosis

1999 • 805 citations

Elevated Levels of Interleukin-6 in Unstable Angina

1996 • 744 citations

Functional CD40 ligand is expressed on human vascular endothelial cells, smooth muscle cells, and macrophages: Implications for CD40–CD40 ligand signaling in atherosclerosis

1997 • 737 citations

Immunization of low density lipoprotein (LDL) receptor-deficient rabbits with homologous malondialdehyde-modified LDL reduces atherogenesis.

1995 • 596 citations

Cytokines and growth factors positively and negatively regulate interstitial collagen gene expression in human vascular smooth muscle cells.

1991 • 591 citations

Interleukin-6 Exacerbates Early Atherosclerosis in Mice

1999 • 522 citations

IL-6-Deficient Mice Are Resistant to Experimental Autoimmune Encephalomyelitis: Roles of IL-6 in the Activation and Differentiation of Autoreactive T Cells

1998 • 448 citations

Atherosclerosis and Coronary Artery Disease

1996 • 438 citations

Cross-regulatory roles of interleukin (IL)-12 and IL-10 in atherosclerosis.

1996 • 428 citations

The Role of Interleukin-4 and Interleukin-12 in the Progression of Atherosclerosis in Apolipoprotein E-Deficient Mice

2003 • 423 citations

Hypercholesterolemia is associated with a T helper (Th) 1/Th2 switch of the autoimmune response in atherosclerotic apo E-knockout mice.

1998 • 421 citations

Interleukin-10 Blocks Atherosclerotic Events In Vitro and In Vivo

1999 • 399 citations

Inhibition of CD40 signaling limits evolution of established atherosclerosis in mice

2000 • 353 citations

Role of Heat Shock Proteins in Atherosclerosis

2002 • 350 citations

T-bet deficiency reduces atherosclerosis and alters plaque antigen-specific immune responses

2005 • 335 citations

The Role of Interleukin 12 in the Development of Atherosclerosis in ApoE-Deficient Mice

1999 • 307 citations

LDL Immunization Induces T-Cell–Dependent Antibody Formation and Protection Against Atherosclerosis

2001 • 297 citations

Positional identification of TNFSF4, encoding OX40 ligand, as a gene that influences atherosclerosis susceptibility

2005 • 276 citations

Expression of Interleukin-10 in Advanced Human Atherosclerotic Plaques

1999 • 267 citations

Influence of Interferon-γ on the Extent and Phenotype of Diet-Induced Atherosclerosis in the LDLR-Deficient Mouse

2003 • 267 citations

Interleukin-4 Deficiency Decreases Atherosclerotic Lesion Formation in a Site-Specific Manner in Female LDL Receptor−/− Mice

2002 • 259 citations

Atherosclerotic lesions in humans. In situ immunophenotypic analysis suggesting an immune mediated response.

1989 • 254 citations

Murine cutaneous leishmaniasis : Susceptibility correlates with differential expansion of helper T-cell subsets

1987 • 212 citations

T Helper–Cell Phenotype Regulates Atherosclerosis in Mice Under Conditions of Mild Hypercholesterolemia

2001 • 211 citations

TH2 Predominant Immune Responses Prevail in Human Abdominal Aortic Aneurysm

2002 • 211 citations

Th2-predominant inflammation and blockade of IFN-γ signaling induce aneurysms in allografted aortas

2004 • 195 citations

Hyperlipidemia and Atherosclerotic Lesion Development in LDL Receptor–Deficient Mice Fed Defined Semipurified Diets With and Without Cholate

1999 • 174 citations

IFN-γDeficiency Exerts Gender-Specific Effects on Atherogenesis in Apolipoprotein E^-/-Mice

2002 • 174 citations

Attenuation of atherogenesis by systemic and local adenovirus‐mediated gene transfer of interleukin‐10 in LDLr ‐/‐ Mice

2001 • 165 citations

Th2-predominant inflammation and blockade of IFN-γ signaling induce aneurysms in allografted aortas

2004 • 162 citations

Differential Regulation of IL-9-Expression after Infection with Leishmania major in Susceptible and Resistant Mice

1993 • 162 citations

Increase in Serum Amyloid A Evoked by Dietary Cholesterol Is Associated With Increased Atherosclerosis in Mice

2004 • 162 citations

The association of c-reactive protein, serum amyloid a and fibrinogen with prevalent coronary heart disease — baseline findings of the PAIS project

2001 • 121 citations

Regulation of major histocompatibility gene expression in human vascular smooth muscle cells.

1989 • 94 citations

Effect of interferon-γ and tumor necrosis factor on the expression of class I and class II major histocompatibility molecules by cultured human umbilical vein endothelial cells

1988 • 78 citations

In Silico Quantitative Trait Locus Map for Atherosclerosis Susceptibility in Apolipoprotein E–Deficient Mice

2003 • 77 citations

Unstable atherosclerotic plaques contain T-cells that respond to Chlamydia pneumoniae

2000 • 76 citations

Circulating adhesion molecules in apoE-deficient mouse strains with different atherosclerosis susceptibility

2005 • 61 citations

MHC class II antigen expression in human vascular smooth muscle cells is induced by interferon-gamma and modulated by tumour necrosis factor and lymphotoxin.

1990 • 56 citations

Genetic analysis of strains C57BL/6J and BALB/cJ for Ath-1, a gene determining atherosclerosis susceptibility in mice

1987 • 35 citations