Site-Specific Chemical Modification of B-Z Junctions in Supercoiled DNA as Detected by Nuclease SI Digestion, Inhibition of Restriction Cleavage and Nucleotide Sequencing

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

THE CHEMISTRY AND BIOLOGY OF LEFT-HANDED Z-DNA

1984 • 1,149 citations

Determination of the number of superhelical turns in simian virus 40 DNA by gel electrophoresis.

1975 • 538 citations

Left-handed Z-DNA is induced by supercoiling in physiological ionic conditions

1982 • 439 citations

Flipping of cloned d(pCpG)n.d(pCpG)n DNA sequences from right- to left-handed helical structure by salt, Co(III), or negative supercoiling.

1982 • 321 citations

Structural specificities of five commonly used DNA nucleases

1984 • 286 citations

Chemical probes of DNA conformation: detection of Z-DNA at nucleotide resolution

1985 • 286 citations

Negatively supercoiled plasmids contain left-handed Z-DNA segments as detected by specific antibody binding

1982 • 285 citations

Left-Handed DNA in Vivo

1987 • 214 citations

Left-handed DNA: from Synthetic Polymers to Chromosomes

1983 • 181 citations

Diethyl pyrocarbonate: a chemical probe for secondary structure in negatively supercoiled DNA.

1985 • 169 citations

The facile generation of covalently closed, circular DNAs with defined negative superhelical densities

1982 • 139 citations

Intervening sequences in human fetal globin genes adopt left-handed Z helices.

1984 • 121 citations

S1 nuclease recognizes DNA conformational junctions between left-handed helical (dT-dG n. dC-dA)n and contiguous right-handed sequences.

1984 • 119 citations

Highly selective chemical modification of cruciform loops by diethyl pyrocarbonate

1986 • 100 citations

Left-handed DNA. Cloning, characterization, and instability of inserts containing different lengths of (dC-dG) in Escherichia coli.

1982 • 98 citations

The reaction of glyoxal with nucleic acid components III. Kinetics of the reaction with monomers

1971 • 88 citations

Diethyl pyrocarbonate: a chemical probe for DNA cruciforms

1986 • 76 citations

Site-specific OsO4 modification of the B-Z junctions formed at the (dA-dC)32 region in supercoiled DNA.

1986 • 72 citations

BAL 31 nuclease as a probe in concentrated salt for the B-Z DNA junction

1983 • 72 citations

Hhalmethylase and restriction endonuclease as probes for B to Z DNA conformational changes in d(GCGC) sequences

1984 • 71 citations

In Z-DNA the sequence G-C-G-C is neither methylated by Hha I methyltransferase nor cleaved by Hha I restriction endonuclease.

1984 • 68 citations

Recognition of the Structural Distortions at the Junctions Between B and Z Segments in Negatively Supercoiled DNA by Osmium Tetroxide

1985 • 58 citations

Restriction endonucleases can be used to study B-Z junctions in supercoiled DNA.

1984 • 54 citations

B-Z DNA junctions contain few, if any, nonpaired bases at physiological superhelical densities.

1985 • 47 citations

Unusual conformational effect exerted by Z-DNA upon its neighboring sequences.

1987 • 45 citations

Reaction conditions affect the specificity of bromoacetaidehyde as a probe for DNA cruciforms and B—Z junctions

1987 • 44 citations

Probing of DNA polymorphic structure in the cell with osmium tetroxide

1988 • 35 citations

Inhibition of restriction endonuclease cleavage due to site-specific chemical modification of the B-Z junction in supercoiled DNA.

1987 • 28 citations

Osmium tetroxide recognized structural distortions at junctions between right- and left-handed DNA in a bacterial cell.

1987 • 26 citations

B-Z Junctions in Supercoiled pRW751 DNA Contain Unpaired Bases or Non-Watson-Crick Base Pairs

1987 • 21 citations

B‐Z DNA junctions are neither highly flexible nor strongly bent

1987 • 18 citations

Method for the preparation of plasmid DNA suitable for physicochemical measurements.

1985 • 5 citations