A pH-dependent Conformational Change of NhaA Na+/H+ Antiporter of Escherichia coli Involves Loop VIII–IX, Plays a Role in the pH Response of the Protein, and Is Maintained by the Pure Protein in Dodecyl Maltoside

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

1989 • 7,496 citations

MUTANTS OF ESCHERICHIA COLI REQUIRING METHIONINE OR VITAMIN B ₁₂

1950 • 2,926 citations

Linearization of the Bradford Protein Assay Increases Its Sensitivity: Theoretical and Experimental Studies

1996 • 1,003 citations

Overproduction and purification of a functional Na+/H+ antiporter coded by nhaA (ant) from Escherichia coli

1991 • 260 citations

Characterization of a Na+/H+ antiporter gene of Escherichia coli.

1987 • 209 citations

Deletion of ant in Escherichia coli Reveals Its Function in Adaptation to High Salinity and an Alternative Na+/H+ Antiporter System(s)

1989 • 184 citations

Physiological role of nhaB, a specific Na+/H+ antiporter in Escherichia coli.

1993 • 179 citations

Sodium-proton antiport in isolated membrane vesicles of Escherichia coli

1978 • 176 citations

Proton-sodium stoichiometry of NhaA, an electrogenic antiporter from Escherichia coli.

1993 • 156 citations

Molecular physiology of Na+/H+ antiporters, key transporters in circulation of Na+ and H+ in cells

1994 • 144 citations

Sequencing of the gene ant which affects the Na+/H+ antiporter activity in Escherichia coli.

1988 • 142 citations

Histidine-226 is part of the pH sensor of NhaA, a Na+/H+ antiporter in Escherichia coli.

1993 • 132 citations

Cloning, sequencing, and expression of the nhaB gene, encoding a Na+/H+ antiporter in Escherichia coli.

1992 • 131 citations

[26] Ion extrusion systems in Escherichia coli

1986 • 122 citations

Histidine 225, a Residue of the NhaA-Na+/H+ Antiporter of Escherichia coli Is Exposed and Faces the Cell Exterior

1997 • 103 citations

Expression of a sodium proton antiporter (NhaA) in Escherichia coli is induced by Na+ and Li+ ions.

1991 • 95 citations

NhaR, a protein homologous to a family of bacterial regulatory proteins (LysR), regulates nhaA, the sodium proton antiporter gene in Escherichia coli.

1992 • 89 citations

An Early Step in Pseudomonas Exotoxin Action Is Removal of the Terminal Lysine Residue, Which Allows Binding to the KDEL Receptor

1997 • 87 citations

Kinetic properties of NhaB, a Na+/H+ antiporter from Escherichia coli

1994 • 78 citations

A Point Mutation (G338S) and Its Suppressor Mutations Affect Both the pH Response of the NhaA-Na+/H+ Antiporter as Well as the Growth Phenotype of Escherichia coli

1998 • 66 citations

Topological Analysis of NhaA, a Na+/H+ Antiporter from Escherichia coli

1996 • 61 citations

Identification and Characterization of Functional Residues in a Na+/H+ Antiporter (NhaA) from Escherichia coli by Random Mutagenesis

1997 • 46 citations

Replacements of Histidine 226 of NhaA-Na+/H+ Antiporter of Escherichia coli

1995 • 44 citations

Probing the Conformation of NhaA, a Na⁺/H⁺ Antiporter from Escherichia coli, with Trypsin

1997 • 39 citations

The Na+-specific interaction between the LysR-type regulator, NhaR, and the nhaA gene encoding the Na+/H+ antiporter of Escherichia coli

1997 • 38 citations

Expression of functional Na⁺/H⁺ antiporters of Helicobacter pylori in antiporter‐deficient Echerichia coli mutants

1999 • 26 citations

In vitro folding of a membrane protein: Effect of denaturation and renaturation on substrate binding by the lactose permease ofEscherichia coli

1998 • 12 citations