In vivo Models of Cerebral Ischemia: Effects of Parenterally Administered NMDA Receptor Glycine Site Antagonists

Elevation of the Extracellular Concentrations of Glutamate and Aspartate in Rat Hippocampus During Transient Cerebral Ischemia Monitored by Intracerebral Microdialysis

1984 • 2,884 citations

Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination.

1986 • 2,584 citations

Glutamate neurotoxicity in cortical cell culture is calcium dependent

1985 • 818 citations

Models for studying long-term recovery following forebrain ischemia in the rat. 2. A 2-vessel occlusion model

1984 • 741 citations

The distribution of hypoglycemic brain damage

1984 • 376 citations

Protective Effect of the Glutamate Antagonist, MK-801 in Focal Cerebral Ischemia in the Cat

1988 • 370 citations

Postischemic Blockade of AMPA but Not NMDA Receptors Mitigates Neuronal Damage in the Rat Brain following Transient Severe Cerebral Ischemia

1992 • 315 citations

Ischemic penumbra in a model of reversible middle cerebral artery occlusion in the rat

1992 • 309 citations

Blockade of the AMPA receptor prevents CA1 hippocampal injury following severe but transient forebrain ischemia in adult rats

1991 • 253 citations

Changes in Extracellular Concentrations of Glutamate, Aspartate, Glycine, Dopamine, Serotonin, and Dopamine Metabolites After Transient Global Ischemia in the Rabbit Brain

1991 • 211 citations

Sevoflurane and Halothane Reduce Focal Ischemic Brain Damage in the Rat

1993 • 192 citations

Calcium accumulation by glutamate receptor activation is involved in hippocampal cell damage after ischemia

1988 • 192 citations

Excitotoxic index — a biochemical marker of selective vulnerability

1991 • 178 citations

Changes in extracellular amino acid neurotransmitters produced by focal cerebral ischemia

1990 • 157 citations

Modulation of excitatory synaptic transmission by glycine and zinc in cultures of mouse hippocampal neurons

1988 • 146 citations

Motor performance in rats exposed to severe forebrain ischemia: effect of fasting and 1,3-butanediol.

1987 • 142 citations

Interactions between the glycine and glutamate binding sites of the NMDA receptor

1993 • 141 citations

Forebrain ischemia induces selective behavioral impairments associated with hippocampal injury in rats.

1991 • 109 citations

Protection against ischemic hippocampal CAI damage in the rat with a new non-NMDA antagonist, NBQX

1992 • 108 citations

The Effects of Dizocilpine Maleate (MK-801), an Antagonist of the N-Methyl-D-Aspartate Receptor, on Neurologic Recovery and Histopathology following Complete Cerebral Ischemia in Primates

1990 • 100 citations

MK-801, an Excitatory Amino Acid Antagonist, Does Not Improve Neurologic Outcome following Cardiac Arrest in Cats

1989 • 67 citations

The effect of NMDA receptor glycine site antagonists on hypoxia-induced neurodegeneration of rat cortical cell cultures

1990 • 66 citations

Influence of moderate hypothermia on ischemic brain damage incurred under hyperglycemic conditions

1991 • 43 citations

Effects of intra-ischemic blood pressure on outcome from 2-vessel occlusion forebrain ischemia in the rat

1992 • 41 citations

Glycine reversal of felbamate hypoxic protection

1993 • 40 citations

A glycine antagonist reduces ischemia-induced CA1 cell loss in vivo

1992 • 37 citations

Glycine is required for NMDA receptor activation: electrophysiological evidence from intact rat hippocampus

1992 • 36 citations

HA-996 (1-hydroxy-3-aminopyrrolidone-2) selectively reduces (NMDA)-mediated brain damage

1989 • 31 citations

Pretreatment with the NMDA antagonist dextrorphan reduces cerebral injury following transient focal ischemia in rabbits

1989 • 26 citations

Minimum Alveolar Concentration for Halothane in the Rat Is Resistant to Effects of Forebrain Ischemia and Reperfusion

1994 • 8 citations

GLYCINE RECEPTOR ANTAGONISM

1994 • 2 citations

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