Behavioral reactivity to aversive stimuli in a transgenic mouse model of impaired glucocorticoid (type II) receptor function: effects of diazepam and FG-7142

Conflict, arousal, and curiosity.

1960 • 5,766 citations

Validation of open : closed arm entries in an elevated plus-maze as a measure of anxiety in the rat

1985 • 5,596 citations

Physiological Functions of Glucocorticoids in Stress and Their Relation to Pharmacological Actions*

1984 • 3,073 citations

Exploration of mice in a black and white test box: Validation as a model of anxiety

1989 • 535 citations

Differences in fear motivated behaviors among inbred mouse strains

1993 • 450 citations

The interplay of learning and anxiety in the elevated plus-maze

1993 • 327 citations

Impaired type II glucocorticoid-receptor function in mice bearing antisense RNA transgene

1992 • 313 citations

Comparison of different behavioral test situations used in psychopharmacology for measurement of anxiety

1994 • 286 citations

Acoustic and Temporal Factors in the Evocation of Startle

1968 • 247 citations

A sensitive open field measure of anxiolytic drug activity

1981 • 242 citations

The role of fear in theories of avoidance learning, flooding, and extinction.

1979 • 214 citations

A cognitive theory of avoidance learning.

1973 • 201 citations

Long‐Term Antidepressant Treatment Reduces Behavioural Deficits in Transgenic Mice with Impaired Glucocorticoid Receptor Function

1995 • 168 citations

Multiple serotonin mechanisms in animal models of anxiety

1993 • 152 citations

The Avoidance Learning Problem

1972 • 120 citations

Bidirectional effects of β-carbolines and benzodiazepines on cognitive processes

1987 • 104 citations

Effect of corticosterone on the enhancement of the acoustic startle reflex by corticotropin releasing factor (CRF)

1994 • 102 citations

Dexamethasone nonsuppression in transgenic mice expressing antisense RNA to the glucocorticoid receptor

1994 • 71 citations

Spatial memory in transgenic mice with impaired glucocorticoid receptor function

1997 • 46 citations

Energy balance and lipid metabolism in transgenic mice bearing an antisense GCR gene construct

1993 • 42 citations

Interactions of anxiolytic and antidepressant drugs with hormones of the hypothalamic-pituitary-adrenal axis

1990 • 39 citations

Continuous slow release of low levels of diazepam produces tolerance to its depressant and anxiolytic effects on the startle reflex

1988 • 34 citations

Behavioral and Endocrine Impact of Impaired Type II Glucocorticoid Receptor Function in a Transgenic Mouse Modela

1994 • 22 citations